Laboratory for Fluorescence Dynamics

A NIH research center for biomedical fluorescence spectroscopy at the University of California, Irvine

Tissue Imaging

Bone tissue

The DIVER microscope system developed at the LFD can image large tissue areas in various imaging modes.

For example, a femur slice from a SMRTmRID mouse is shown in bright field (top), second harmonic generation (SHG, middle), and fluorescence lifetime imaging (FLIM, bottom) modes. The FLIM image is phasor mapped to segment Collagen I (red) from Collagen III (turquoise) rich regions.

See Sci Rep. 2015; 5: 13378.


News

Welcome to the LFD

The Laboratory for Fluorescence Dynamics (LFD) is a national research resource center for biomedical fluorescence spectroscopy, supported by the National Institute of General Medical Sciences (NIGMS, 2P41GM103540) divisions of the National Institutes of Health (NIH) and the University of California, Irvine (UCI).

The founder and Principal Investigator of the LFD is Enrico Gratton. The Co-Investigator is Michelle Digman.

The LFD's main activities are:

  • Services and Resources: the LFD provides a state-of-the-art laboratory for fluorescence measurements, microscopy and spectroscopy, with technical assistance to visiting scientists.
  • Research and Development: the LFD designs, tests, and implements advances in the technology of hardware, software, and biomedical applications.
  • Training and Dissemination: the LFD disseminates knowledge of fluorescence spectroscopic principles, instrumentation, and applications to the scientific community.

Read more about the LFD's activities, history, funding, and organization.

The content on this website is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the University of California, Irvine.