Laboratory for Fluorescence Dynamics

A NIH research center for biomedical fluorescence spectroscopy at the University of California, Irvine

Journal Articles

Refereed journal articles, authored or coauthored by members of the Laboratory for Fluorescence Dynamics (LFD) from 1987 to present. Access to most PDF documents is password protected due to copyright restrictions. Reprints can be requested from the authors.

2017

  1. Liang EI, Mah EJ, Yee AF, Digman MA.
    Correlation of focal adhesion assembly and disassembly with cell migration on nanotopography.
    Integr Biol (Camb). 2017; 9(2): 145-155. PMCID: PMC5399776
  2. de Vega GB, Ceballos JA, Anzalone A, Digman MA, Gratton E.
    A laser-scanning confocal microscopy study of carrageenan in red algae from seaweed farms near the Caribbean entrance of the Panama Canal.
    J Appl Phycol. 2017; 29(1): 495-508.
  3. Romero-López M, Trinh AL, Sobrino A, Hatch MMS, Keating MT, Fimbres C, Lewis DE, Gershon PD, Botvinick EL, Digman MA, Lowengrub JS, Hughes CCW.
    Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.
    Biomaterials. 2017; 116: 118-129. PMCID: PMC5226635

2016

  1. Porcaro F, Miao Y, Kota R, Haun JB, Polzonetti G, Battocchio C, Gratton E.
    Fluctuation spectroscopy analysis of glucose capped gold nanoparticles.
    Langmuir. 2016; 32(50): 13409-13417.
  2. Malacrida L, Astrada S, Briva A, Bollati-Fogolín M, Gratton E, Bagatolli LA.
    Spectral Phasor analysis of LAURDAN fluorescence in live A549 lung cells to study the hydration and time evolution of intracellular lamellar body-like structures.
    Biochim Biophys Acta. 2016; 1858(11): 2625-2635. PMCID: PMC5045802
  3. Ranjit S, Dobrinskikh E, Montford J, Dvornikov A, Lehman A, Orlicky DJ, Nemenoff R, Gratton E, Levi M, Furgeson S.
    Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis.
    Kidney Int. 2016; 90(5): 1123-1128.
  4. Aguilar-Arnal L, Ranjit S, Stringari C, Orozco-Solis R, Gratton E.
    Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species.
    Proc Natl Acad Sci USA. 2016; 113(45): 12715-12720. PMCID: PMC5111721
  5. Sameni S, Syed A, Marsh JL, Digman MA.
    The phasor-FLIM fingerprints reveal shifts from OXPHOS to enhanced glycolysis in Huntington Disease.
    Sci Rep. 2016; 6: 34755. PMCID: PMC5054433
  6. Cinco R, Digman MA, Gratton E, Luderer U.
    Spatial characterization of bioenergetics and metabolism of primordial to preovulatory follicles in whole ex vivo murine ovary.
    Biol Reprod. 2016; 95(6): 129. PMCID: PMC5315427
  7. Qiu Y, Lin CY, Hinkle P, Plett TS, Yang C, Chacko JV, Digman MA, Yeh LH, Hsu JP, Siwy ZS.
    Highly charged particles cause a larger current blockage in micropores compared to neutral particles.
    ACS Nano. 2016; 10(9): 8413-8422.
  8. Digiacomo L, Digman MA, Gratton E, Caracciolo G.
    Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles.
    Acta Biomater. 2016; 42: 189-198.
  9. Serebryannyy LA, Parilla M, Annibale P, Cruz CM, Laster K, Gratton E, Kudryashov D, Kosak ST, Gottardi CJ, de Lanerolle P.
    Persistent nuclear actin filaments inhibit transcription by RNA polymerase II.
    J Cell Sci. 2016; 129(18): 3412-3425. PMCID: PMC5047679
  10. Chen H, Gratton E, Digman MA.
    Self-assisted optothermal trapping of gold nanorods under two-photon excitation.
    Methods Appl Fluoresc. 2016; 4(3): 035003.
  11. Dvornikov A Gratton E.
    Imaging in turbid media: a transmission detector gives 2-3 order of magnitude enhanced sensitivity compared to epi-detection schemes.
    Biomed Opt Express. 2016; 7(9): 3747-3755. PMCID: PMC5030047
  12. Di Rienzo C, Gratton E, Beltram F, Cardarelli F.
    Spatiotemporal fluctuation analysis: a powerful tool for the future nanoscopy of molecular processes.
    Biophys J. 2016; 111(4): 679-685. PMCID: PMC5002078
  13. Di Rienzo C, Cardarelli F, Di Luca M, Beltram F, Gratton E.
    Diffusion tensor analysis by two-dimensional pair correlation of fluorescence fluctuations in cells.
    Biophys J. 2016; 111(4): 841-851. PMCID: PMC5002073
  14. Sobrino A, Phan DTT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CCW.
    3D microtumors in vitro supported by perfused vascular networks.
    Sci Rep. 2016; 6, 31589. PMCID: PMC4994029
  15. Ranjit S, Dvornikov A, Levi M, Furgeson S, Gratton E.
    Characterizing fibrosis in UUO mice model using multiparametric analysis of phasor distribution from FLIM images.
    Biomed Opt Express. 2016; 7(9): 3519-3530. PMCID: PMC5030029
  16. Scipion L, Gratton E, Diaspro A, Lanzanò L.
    Phasor analysis of local ICS detects heterogeneity in size and number of intracellular vesicles.
    Biophys J. 2016; 111(3): 619-629. PMCID: PMC4982927
  17. Szymanska AF, Heylman C, Datta R, Gratton E, Nenadic Z.
    Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC.
    Comput Biol Med. 2016; 75: 109-117. PMCID: PMC4938768
  18. Ma N, Digman MA, Malacrida L, Gratton E.
    Measurements of absolute concentrations of NADH in cells using the phasor FLIM method.
    Biomed Opt Express. 2016; 7(7): 2441-2452. PMCID: PMC4948605
  19. Noutsi P, Gratton E, Chaieb S.
    Assessment of membrane fluidity fluctuations during cellular development reveals time and cell type specificity.
    PLoS One. 2016; 11(6): e0158313. PMCID: PMC4928918
  20. Hedde PN Gratton E.
    Selective plane illumination microscopy with a light sheet of uniform thickness formed by an electrically tunable lens.
    Microsc Res Tech. 2016; [Epub ahead of print].
  21. Clark NM, Hinde E, Winter CM, Fisher AP, Crosti G, Blilou I, Gratton E, Benfey PN, Sozzani R.
    Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy.
    eLife. 2016; 5: e14770. PMCID: PMC4946880
  22. Cardarelli F, Digiacomo L, Marchini C, Amici A, Salomone F, Fiume G, Rossetta A, Gratton E, Pozzi D, Caracciolo G.
    The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery.
    Sci Rep. 2016; 11(6): 25879. PMCID: PMC4863168
  23. Lin S, Hedde PN, Venugopalan V, Gratton E, Khine M.
    Multi-scale silica structures for improved HIV-1 Capsid (p24) antigen detection.
    Analyst. 2016; 141(13): 4181-4188. PMCID: PMC4924925
  24. Borrego SL, Fahrmann J, Datta R, Stringari C, Grapov D, Zeller M, Chen Y, Wang P, Baldi P, Gratton E, Fiehn O, Kaiser P.
    Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells.
    Cancer Metab. 2016; 4: 9. PMCID: PMC4852440
  25. Alfonso-García A, Smith TD, Datta R, Luu TU, Gratton E, Potma EO, Liu WF.
    Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy.
    J Biomed Opt. 2016; 21(4): 46005. PMCID: PMC4833856
  26. Sosnik J, Zheng L, Rackauckas CV, Digman MA, Gratton E, Nie Q, Schilling TF.
    Noise modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the embryonic zebrafish hindbrain.
    eLife. 2016; 5: e14034. PMCID: PMC4829421
  27. Datta R, Heylman C, George SC, Gratton E.
    Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes.
    Biomed Opt Express. 2016; 7(5): 1690-701. PMCID: PMC4871074
  28. Hinde E, Pandžić E, Yang Z, Ng IHW, Jans DA, Bogoyevitch MA, Gratton E, Gaus K.
    Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness.
    Nat Commun. 2016; 7: 11047. PMCID: PMC4820838
  29. Brenner MD, Zhou R, Conway DE, Lanzanò L, Gratton E, Schwartz MA, Ha T.
    Spider silk peptide is a compact, linear nano-spring ideal for intracellular tension sensing.
    Nano Lett. 2016; 16(3): 2096-2102. PMCID: PMC4851340
  30. Wang B, Rong X, Duerr MA, Hermanson DJ, Hedde PN, Wong JS, de Vallim TQA, Cravatt BF, Gratton E, Ford DA, Tontonoz P.
    Intestinal phospholipid remodeling is required for dietary-lipid uptake and survival on a high-fat diet.
    Cell Metab. 2016; 23: 1-13. PMCID: PMC4785086
  31. Annibale P, Dvornikov A, Gratton E.
    Optical measurement of focal offset in tunable lenses.
    Opt Express. 2016; 24(2): 1031-1036. PMCID: PMC4741313
  32. Moore JS, Xantheas SS, Grate JW, Wietsma TW, Gratton E, Vasdekis AE.
    Modular polymer biosensors by solvent immersion imprint lithography.
    J Polym Sci B Polym Phys. 2016; 54(1): 98-103. PMCID: PMC5111810

2015

  1. Heylman C, Datta R, Sobrino A, George S, Gratton E.
    Supervised machine learning for classification of the electrophysiological effects of chronotropic drugs on human induced pluripotent stem cell-derived cardiomyocytes.
    PLoS One. 2015; 10(12): e0144572. PMCID: PMC4690607
  2. Chen H, Holst G, Gratton E.
    Modulated CMOS camera for fluorescence lifetime microscopy.
    Microsc Res Tech. 2015; 78(12): 1075-1081. PMCID: PMC4770881
  3. Lakhani VV, Hinde E, Gratton E, Elston TC.
    Spatio-temporal regulation of Rac1 mobility by actin islands.
    PLoS One. 2015; 10(11): e0143753. PMCID: PMC4659588
  4. Malacrida L, Gratton E, Jameson DM.
    Model-free methods to study membrane environmental probes: a comparison of the spectral phasor and generalized polarization approaches.
    Methods Appl Fluoresc. 2015; 3(4): 047001. PMCID: PMC4862737
  5. Zhang K, Kang DK, Ali MM, Liu L, Labanieh L, Lu M, Riazifar H, Nguyen TN, Zell JA, Digman MA, Gratton E, Li J, Zhao W.
    Digital quantification of miRNA directly in plasma using integrated comprehensive droplet digital detection.
    Lab Chip. 2015; 15(21): 4217-4226. PMCID: PMC4631652
  6. Tan Z, Dai W, van Erp TGM, Overman J, Demuro A, Digman MA, Hatami A, Albay R, Sontag EM, Potkin KT, Ling S, Macciardi F, Bunney WE, Long JD, Paulsen JS, Ringman JM, Parker I, Glabe C, Thompson LM, Chiu W, Potkin SG.
    Huntington’s disease cerebrospinal fluid seeds aggregation of mutant huntingtin.
    Mol Psychiatry. 2015; 20(11): 1286-1293. PMCID: PMC4718563
  7. Adu-Gyamfi E, Johnson KA, Fraser ME, Scott JL, Soni SP, Jones KR, Digman MA, Gratton E, Tessier CR, Stahelin RV.
    Host cell plasma membrane phosphatidylserine regulates the assembly and budding of the Ebola virus.
    J Virol. 2015; 89(18): 9440-9453. PMCID: PMC4542376
  8. Mieruszynski S, Digman MA, Gratton E, Jones MR.
    Characterization of exogenous DNA mobility in live cells through fluctuation correlation spectroscopy.
    Sci Rep. 2015; 5: 13848. PMCID: PMC4564760
  9. Hedde PN, Ranjit S, Gratton E.
    3D fluorescence anisotropy imaging using selective plane illumination microscopy.
    Opt Express. 2015; 23(17): 22308-22317. PMCID: PMC4646523
  10. Ranjit S, Dvornikov A, Stakic M, Hong SH, Levi M, Evans RM, Gratton E.
    Imaging fibrosis and separating collagens using second harmonic generation and phasor approach to fluorescence lifetime imaging.
    Sci Rep. 2015; 5: 13378. PMCID: PMC4543938
  11. Hendrix J, Baumgärtel V, Schrimpf W, Ivanchenko S, Digman MA, Gratton E, Kräusslich HG, Müller B, Lamb DC.
    Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers.
    J Cell Biol. 2015; 210(4): 629-646. PMCID: PMC4539982
  12. Hinde E, Cardarelli F, Gratton E.
    Spatiotemporal regulation of Heterochromatin Protein 1- alpha oligomerization and dynamics in live cells.
    Sci Rep. 2015; 5: 12001. PMCID: PMC4523856
  13. Ito A, Hong C, Rong X, Zhu X, Tarling EJ, Hedde PN, Gratton E, Parks J, Tontonoz P.
    LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.
    eLife. 2015; 4: e08009. PMCID: PMC4517437
  14. Plotegher N, Stringari C, Jahid S, Veronesi M, Girotto S, Gratton E, Bubacco L.
    NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells.
    FASEB J. 2015; 29(6): 2484-2494. PMCID: PMC4447231
  15. Hedde PN Gratton E.
    Active focus stabilization for upright selective plane illumination microscopy.
    Opt Express. 2015; 23(11): 14707-14714. PMCID: PMC4523369
  16. Mieruszynski S, Briggs C, Digman MA, Gratton E, Jones MR.
    Live cell characterization of DNA aggregation delivered through lipofection.
    Sci Rep. 2015; 5: 10528. PMCID: PMC4444954
  17. Annibale P, Dvornikov A, Gratton E.
    Electrically tunable lens speeds up 3D orbital tracking.
    Biomed Opt Express. 2015; 6(6): 2181-2190. PMCID: PMC4473752
  18. Datta R, Alfonso-García A, Cinco R, Gratton E.
    Fluorescence lifetime imaging of endogenous biomarker of oxidative stress.
    Sci Rep. 2015; 5: 9848. PMCID: PMC4438616
  19. Anzalone A, Gabriel M, Estrada LC, Gratton E.
    Spectral properties of single gold nanoparticles in close proximity to biological fluorophores excited by 2-photon excitation.
    PLoS One. 2015; 10(4): e0124975. PMCID: PMC4409109
  20. Olivera-Couto A, Salzman V, Mailhos M, Digman MA, Gratton E, Aguilar PS.
    Eisosomes are dynamic plasma membrane domains showing Pil1-Lsp1 heteroligomer binding equilibrium.
    Biophys J. 2015; 108(7): 1633-1644. PMCID: PMC4390835
  21. Lanzanò L, Hernández IC, Castello M, Gratton E, Diaspro A, Vicidomini G.
    Encoding and decoding spatio-temporal information for super-resolution microscopy.
    Nat Commun. 2015; 6, 6701. PMCID: PMC4384168
  22. Rong X, Wang B, Dunham MM, Hedde PN, Wong JS, Gratton E, Young SG, Ford DA, Tontonoz P.
    Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion.
    eLife. 2015; 4: e06557. PMCID: PMC4400582
  23. Moens PDJ, Digman MA, Gratton E.
    Modes of diffusion of Cholera toxin bound to GM1 on live cell membrane by image mean square displacement analysis.
    Biophys J. 2015; 108(6): 1448-1458. PMCID: PMC4375681
  24. Perumal V, Krishnan K, Gratton E, Dharmarajan AM, Fox SA.
    Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a.
    Int J Biochem Cell Biol. 2015; 64: 91-96. PMCID: PMC4464842
  25. Annibale P Gratton E.
    Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging.
    Sci Rep. 2015; 5, 9258. PMCID: PMC4365385
  26. Chen H, Gratton E, Digman MA.
    Spectral properties and dynamics of gold nanorods revealed by EMCCD-based spectral phasor method.
    Microsc Res Tech. 2015; 78(4): 283-293. PMCID: PMC4404027
  27. Stringari C, Wang H, Geyfman M, Crosignani V, Kumar V, Takahashi JS, Andersen B, Gratton E.
    In vivo single-cell detection of metabolic oscillations in stem cells.
    Cell Rep. 2015; 10(1): 1-7. PMCID: PMC4340841

2014

  1. di Rienzo C, Piazza V, Gratton E, Beltram F, Cardarelli F.
    Probing short-range protein Brownian motion in the cytoplasm of living cells.
    Nat Commun. 2014; 5: 5891. PMCID: PMC4281647
  2. Ranjit S, Dvornikov AS, Holland D, Reinhart GD, Jameson DM, Gratton E.
    Application of three-photon excitation FCS to the study of protein oligomerization.
    J Phys Chem B. 2014; 118(50): 14627-14631. PMCID: PMC4275161
  3. Ranjit S, Lanzanò L, Gratton E.
    Mapping diffusion in a living cell via the phasor approach.
    Biophys J. 2014; 107(12): 2775-2785. PMCID: PMC4269802
  4. Hedde PN, Stakic M, Gratton E.
    Rapid measurement of molecular transport and interaction inside living cells using single plane illumination.
    Sci Rep. 2014; 4: 7048. PMCID: PMC4231332
  5. Kang DK, Ali MM, Zhang K, Huang SS, Peterson E, Digman MA, Gratton E, Zhao W.
    Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection.
    Nat Commun. 2014; 5: 5427. PMCID: PMC4243214
  6. Bonaventura G, Barcellona ML, Golfetto O, Nourse JL, Flanagan LA, Gratton E.
    Laurdan monitors different lipids content in eukaryotic membrane during embryonic neural development.
    Cell Biochem Biophys. 2014; 70(2): 785-794. PMCID: PMC4228983
  7. Adu-Gyamfi E, Soni SP, Jee CS, Digman MA, Gratton E, Stahelin RV.
    A loop region in the N-terminal domain of Ebola virus VP40 is important in viral assembly, budding, and egress.
    Viruses. 2014; 6(10): 3837-3854. PMCID: PMC4213565
  8. di Rienzo C, Gratton E, Beltram F, Cardarelli F.
    From fast fluorescence imaging to molecular diffusion law on live cell membranes in a commercial microscope.
    J Vis Exp. 2014; (92), e51994. PMCID: PMC4461222
  9. Anzalone A, Annibale P, Gratton E.
    3D orbital tracking in a modified two-photon microscope: an application to the tracking of intracellular vesicles.
    J Vis Exp. 2014; (92), e51794. PMCID: PMC4274936
  10. Nicolai E, Garau S, Favalli C, D’Agostini C, Gratton E, Motolese G, Rosato N.
    Evaluation of BiesseBioscreen as a new methodology for bacteriuria screening.
    New Microbiol. 2014; 37(4): 495-501. PMCID: PMC4273739
  11. Subashchandrabose SR, Krishnan K, Gratton E, Mallavarapu M, Naidu R.
    Potential of fluorescence imaging techniques to monitor mutagenic PAH uptake by microalga.
    Environ Sci Technol. 2014; 48(16): 9152-9160. PMCID: PMC4140530
  12. Bachir AI, Zareno J, Moissoglu K, Plow EF, Gratton E, Horwitz AR.
    Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions.
    Curr Biol. 2014; 24(16): 1845-1853. PMCID: PMC4138543
  13. Pate KT, Stringari C, Sprowl-Tanio S, Wang K, TeSlaa T, Hoverter NP, McQuade MM, Garner C, Digman MA, Teitell MA, Edwards RA, Gratton E, Waterman ML.
    Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer.
    EMBO J. 2014; 33(13): 1454-73. PMCID: PMC4194089
  14. Hinde E, Kong X, Yokomori K, Gratton E.
    Chromatin dynamics during DNA repair revealed by pair correlation analysis of molecular flow in the nucleus.
    Biophys J. 2014; 107(1): 55-65. PMCID: PMC4119266
  15. Chiu CL, Aguilar JS, Tsai CY, Wu G, Gratton E, Digman MA.
    Nanoimaging of focal adhesion dynamics in 3D.
    PLoS One. 2014; 9(6): e99896. PMCID: PMC4069057
  16. Plotegher N, Gratton E, Bubacco L.
    Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells.
    Biochim Biophys Acta. 2014; 1840(6): 2014-2024. PMCID: PMC4088272
  17. Lanzanò L Gratton E.
    Orbital single particle tracking on a commercial confocal microscope using piezoelectric stage feedback.
    Methods Appl Fluoresc. 2014; 2(2): 024010. PMCID: PMC4235585
  18. Crosignani V, Jahid S, Dvornikov AS, Gratton E.
    A deep tissue fluorescence imaging system with enhanced SHG detection capabilities.
    Microsc Res Tech. 2014; 77(5): 368-373. PMCID: PMC4009694
  19. Sharma H, Digman MA, Felsinger N, Gratton E, Khine M.
    Enhanced emission of fluorophores on shrink-induced wrinkled composite structures.
    Optical Materials Express. 2014; 4(4): 753-763. PMCID: PMC4220269
  20. Jaureguiberry MS, Tricerri MA, Sánchez SA, Finarelli GS, Montanaro MA, Prieto ED, Rimoldi OJ.
    Role of plasma membrane lipid composition on cellular homeostasis: learning from cell line models expressing fatty acid desaturases.
    Acta Biochim Biophys Sin (Shanghai). 2014; 46(4): 273-282. PMCID: PMC3967655
  21. Paladino S, Lebreton S, Tivodar S, Formiggini F, Ossato G, Gratton E, Tramier M, Coppey-Moisan M, Zurzolo C.
    Golgi sorting regulates organization and activity of GPI proteins at apical membranes.
    Nat Chem Biol. 2014; 10(5): 350-357. PMCID: PMC4027978
  22. Annibale P Gratton E.
    Advanced fluorescence microscopy methods for the real-time study of transcription and chromatin dynamics.
    Transcription. 2014; 5(2), e28425. PMCID: PMC4214231
  23. Pozzi D, Marchini C, Cardarelli F, Salomone F, Coppola S, Montani M, Zabaleta ME, Digman MA, Gratton E, Colapicchioni V, Caracciolo G.
    Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: Interplay between nanostructure and composition.
    Biochim Biophys Acta. 2014; 1838(3): 957-967. PMCID: PMC3940149
  24. Hinde E, Yokomori K, Gaus K, Hahn KM, Gratton E.
    Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation.
    Sci Rep. 2014; 4, 4219. PMCID: PMC3936235
  25. O’Carrigan A, Hinde E, Lu N, Xu XQ, Duan H, Huang G, Maka M, Bellottia B, Chen ZH.
    Effects of light irradiance on stomatal regulation and growth of tomato.
    Environ Exp Bot. 2014; 98: 65-73.
  26. James NG, Digman MA, Ross JA, Barylko B, Wang L, Li J, Chen Y, Mueller JD, Gratton E, Albanesi JP, Jameson DM.
    A mutation associated with centronuclear myopathy enhances the size and stability of dynamin 2 complexes in cells.
    Biochim Biophys Acta. 2014; 1840(1): 315-321. PMCID: PMC3859711

2013

  1. Gehricke JG, Polzonetti CM, Caburian C, Gratton E.
    Prefrontal hemodynamic changes during cigarette smoking in young adult smokers with and without ADHD.
    Pharmacol Biochem Behav. 2013; 112: 78-81. PMCID: PMC3854671
  2. Chiu CL, Digman MA, Gratton E.
    Measuring actin flow in 3D cell protrusions.
    Biophys J. 2013; 105(8): 1746-1755. PMCID: PMC3797595
  3. Chiu CL Gratton E.
    Axial super resolution topography of focal adhesion by confocal microscopy.
    Microsc Res Tech. 2013; 76(10): 1070-1078. PMCID: PMC3871876
  4. Leproux A, Durkin A, Compton M, Cerussi AE, Gratton E, Tromberg BJ.
    Assessing tumor contrast in radiographically dense breast tissue using Diffuse Optical Spectroscopic Imaging (DOSI).
    Breast Cancer Res. 2013; 15(5): R89. PMCID: PMC3979060
  5. Cutrale F, Salih A, Gratton E.
    Spectral Phasor approach for fingerprinting of photo-activatable fluorescent proteins Dronpa, Kaede and KikGR.
    Method Appl Fluoresc. 2013; 1(3): 35001. PMCID: PMC3771857
  6. Chiu CL, Digman MA, Gratton E.
    Cell matrix remodeling ability shown by image spatial correlation.
    J Biophys. 2013; 2013, 532030. PMCID: PMC3725897
  7. di Rienzo C, Gratton E, Beltram F, Cardarelli F.
    Fast spatiotemporal correlation spectroscopy to determine protein lateral diffusion laws in live cell membranes.
    Proc Natl Acad Sci USA. 2013; 110(30): 12307/12. PMCID: PMC3725058
  8. Skinner JP, Swift KM, Ruan Q, Perfetto S, Gratton E, Tetin S.
    Simplified confocal microscope for counting particles at low concentrations.
    Rev Sci Instrum. 2013; 84(7): 074301. PMCID: PMC3724729
  9. Altamore I, Lanzanò L, Gratton E.
    Dual channel detection of ultra low concentration of bacteria in real time by scanning fluorescence correlation spectroscopy.
    Meas Sci Technol. 2013; 24(6): 065702. PMCID: PMC3770197
  10. Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA.
    Fluid shear stress on endothelial cells modulates mechanical tension across VE-Cadherin and PECAM-1.
    Curr Biol. 2013; 23(11): 1024-1030. PMCID: PMC3676707
  11. Alexander BS, Gelb AW, Mantulin WW, Cerussi AE, Tromberg BJ, Yu Z, Lee C, Meng L.
    Impact of stepwise hyperventilation on cerebral tissue oxygen saturation in anesthetized patients: a mechanistic study.
    Acta Anaesthesiol Scand. 2013; 57(5): 604-612. PMCID: PMC3992996
  12. Torno K, Wright BK, Jones MR, Digman MA, Gratton E, Phillips M.
    Real-time analysis of metabolic activity within lactobacillus acidophilus by phasor fluorescence lifetime imaging microscopy of NADH.
    Curr Microbiol. 2013; 66(4): 365-367.
  13. Golfetto O, Hinde E, Gratton E.
    Laurdan fluorescence lifetime discriminates Cholesterol content from changes in fluidity in living cell membranes.
    Biophys J. 2013; 104(6): 1238-1247. PMCID: PMC3602759
  14. Krasieva TB, Stringari C, Liu F, Sun CH, Kong Y, Balu M, Meyskens FL, Gratton E, Tromberg BJ.
    Two-photon excited fluorescence lifetime imaging and spectroscopy of melanins in vitro and in vivo.
    J Biomed Opt. 2013; 18(3): 31107. PMCID: PMC3595716
  15. Chen H Gratton E.
    A practical implementation of multifrequency widefield frequency-domain fluorescence lifetime imaging microscopy.
    Microsc Res Tech. 2013; 76(3): 282-289. PMCID: PMC3742114
  16. Dobrinskikh E, Lanzano L, Rachelson J, Cranston D, Moldovan R, Lei T, Gratton E, Doctor RB.
    Shank2 contributes to the apical retention and intracellular redistribution of NaPiIIa in OK cells.
    Am J Physiol Cell Physiol. 2013; 304(6): C561-573. PMCID: PMC3674434
  17. Andrews LM, Jones MR, Digman MA, Gratton E.
    Detecting Pyronin Y labeled RNA transcripts in live cell microenvironments by phasor-FLIM analysis.
    Methods Appl Fluoresc. 2013; 1(1): 015001. PMCID: PMC3929300
  18. Coppola S, Pozzi D, de Sanctis SC, Digman MA, Gratton E, Caracciolo G.
    Quantitative measurement of intracellular transport of nanocarriers by spatio-temporal image correlation spectroscopy.
    Methods Appl Fluoresc. 2013; 1(1): 015005. PMCID: PMC3871877
  19. Adu-Gyamfi E, Soni SP, Xue Y, Digman MA, Gratton E, Stahelin RV.
    The Ebola virus matrix protein penetrates into the plasma membrane: A key step in VP40 oligomerization and viral egress.
    J Biol Chem. 2013; 288(8): 5779-5789. PMCID: PMC3581432
  20. Coppola S, Cardarelli F, Pozzi D, Estrada LC, Digman MA, Gratton E, Bifone A, Marianecci C, Caracciolo G.
    The role of cytoskeleton networks on lipid-mediated delivery of DNA.
    Ther Deliv. 2013; 4(2): 191-202. PMCID: PMC3771858
  21. Li K, Markosyan RM, Zheng YM, Golfetto O, Bungart B, Li M, Ding S, He Y, Liang C, Lee JC, Gratton E, Cohen FS, Liu SL.
    IFITM Proteins restrict viral membrane hemifusion.
    PLoS Pathog. 2013; 9(1): e1003124. PMCID: PMC3554583
  22. Hinde E, Digman MA, Hahn KM, Gratton E.
    Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM.
    Proc Natl Acad Sci USA. 2013; 110(1): 135-140. PMCID: PMC3538204
  23. Andrews LM, Jones MR, Digman MA, Gratton E.
    Spectral phasor analysis of Pyronin Y labeled RNA microenvironments in living cells.
    Biomed Opt Express. 2013; 4(1): 171-177. PMCID: PMC3539199
  24. de Torre DL, Gordon EA, Digman MA, Stakic M, Häberlein H, Gratton E, Caballero-George C.
    Raster Image Correlation Spectroscopy in Live cells expressing endothelin ETA receptor.
    Current Trends in Biotechnology and Pharmacy. 2013; 7(1): 499-504.

2012

  1. Hinde E, Cardarelli F, Chen A, Khine M, Gratton E.
    Tracking the mechanical dynamics of human embryonic stem cell chromatin.
    Epigenetics Chromatin. 2012; 5(1): 20. PMCID: PMC3570407
  2. Whiteside MD, Digman MA, Gratton E, Treseder KK.
    Organic nitrogen uptake by arbuscular mycorrhizal fungi in a boreal forest.
    Soil Biol Biochem. 2012; 55: 7-13. PMCID: PMC3871874
  3. Wright BK, Andrews LM, Jones MR, Stringari C, Digman MA, Gratton E.
    Phasor-flim analysis of NADH distribution and localization in the nucleus of live progenitor myoblast cells.
    Microsc Res Tech. 2012; 75(12): 1717-1722. PMCID: PMC3635844
  4. Wigal SB, Polzonetti CM, Stehli A, Gratton E.
    Phase synchronization of oxygenation waves in the frontal areas of children with attention-deficit hyperactivity disorder detected by optical diffusion spectroscopy correlates with medication.
    J Biomed Opt. 2012; 17(12): 127002. PMCID: PMC3518849
  5. Crosignani V, Dvornikov AS, Aguilar JS, Stringari C, Edwards R, Mantulin WW, Gratton E.
    Deep tissue fluorescence imaging and in vivo biological applications.
    J Biomed Opt. 2012; 17(11): 116023. PMCID: PMC3494495
  6. Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV.
    Single-particle tracking demonstrates that actin coordinates the movement of the Ebola virus matrix protein.
    Biophys J. 2012; 103(9): L41-L43. PMCID: PMC3491695
  7. Stringari C, Nourse JL, Flanagan LA, Gratton E.
    Phasor fluorescence lifetime microscopy of free and protein-bound NADH reveals neural stem cell differentiation potential.
    PLoS One. 2012; 7(11): e48014. PMCID: PMC3489895
  8. Cutrale F Gratton E.
    Inclined selective plane illumination microscopy adaptor for conventional microscopes.
    Microsc Res Tech. 2012; 75(11): 1461-1466. PMCID: PMC3742098
  9. Giral H, Cranston D, Lanzanò L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi M.
    NHE3 regulatory factor 1 (NHERF1) modulates intestinal Na-dependent phosphate transporter (NaPi-2b) expression in apical microvilli.
    J Biol Chem. 2012; 287(42): 35047-35056. PMCID: PMC3471691
  10. Arnesano C, Santoro Y, Gratton E.
    Digital parallel frequency-domain spectroscopy for tissue imaging.
    J Biomed Opt. 2012; 17(9): 096014. PMCID: PMC3442105
  11. Lanzanò L Gratton E.
    Measurement of distance with the nanoscale precise imaging by rapid beam oscillation method.
    Microsc Res Tech. 2012; 75(9): 1253-1264. PMCID: PMC3426651
  12. Coppola S, Estrada LC, Digman MA, Pozzi D, Cardarelli F, Gratton E, Caracciolo G.
    Intracellular trafficking of cationic liposome-DNA complexes in living cells.
    Soft Matter. 2012; 8(30): 7919-7927. PMCID: PMC4138718
  13. Stringari C, Edwards RA, Pate KT, Waterman ML, Donovan PJ, Gratton E.
    Metabolic trajectory of cellular differentiation in small intestine by phasor fluorescence lifetime microscopy of NADH.
    Sci Rep. 2012; 2: 568. PMCID: PMC3416911
  14. Wright BK, Andrews LM, Markham J, Jones MR, Stringar C, Digman MA, Gratton E.
    NADH distribution in live progenitor stem cells by phasor-fluorescence lifetime image microscopy.
    Biophys J. 2012; 103(1): L7-L9. PMCID: PMC3388207
  15. Cardarelli F, Lanzanò L, Gratton E.
    Capturing directed molecular motion in the nuclear pore complex of live cells.
    Proc Natl Acad Sci USA. 2012; 109(25): 9863-9868. PMCID: PMC3382504
  16. Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV.
    Investigation of Ebola VP40 assembly and oligomerization in live cells using number and brightness analysis.
    Biophys J. 2012; 102(11): 2517-2525. PMCID: PMC3368128
  17. James NG, Digman MA, Gratton E, Barylko B, Ding X, Albanesi JP, Goldberg MS, Jameson DM.
    Number and brightness analysis of LRRK2 oligomerization in live cells.
    Biophys J. 2012; 102(11): L41-L43. PMCID: PMC3368136
  18. Battisti A, Digman MA, Gratton E, Storti B, Beltram F, Bizzarri R.
    Intracellular pH measurements made simple by fluorescent protein probes and the phasor approach to fluorescence lifetime imaging.
    Chem Commun (Camb). 2012; 48(42): 5127-5129. PMCID: PMC3742097
  19. Stringari C, Gratton E, Sierra R, Donovan PJ.
    Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopy.
    J Biomed Opt. 2012; 17(7): 046012. PMCID: PMC3381030
  20. Sánchez SA, Tricerri MA, Gratton E.
    Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo.
    Proc Natl Acad Sci USA. 2012; 109(19): 7314-7319. PMCID: PMC3358851
  21. Montecinos-Franjola F, Ross JA, Sánchez SA, Brunet JE, Lagos R, Jameson DM, Monasterio O.
    Studies on the dissociation and urea-induced unfolding of FtsZ support the dimer nucleus polymerization mechanism.
    Biophys J. 2012; 102(9): 2176-2185. PMCID: PMC3341561
  22. Digman MA Gratton E.
    Scanning image correlation spectroscopy.
    Bioessays. 2012; 34(5): 377-385. PMCID: PMC3635842
  23. Meng L, Gelb AW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Mantulin WW.
    Impact of phenylephrine administration on cerebral tissue oxygen saturation and blood volume is modulated by carbon dioxide in anaesthetized patients.
    Br J Anaesth. 2012; 108(5): 815-822. PMCID: PMC3325051
  24. Zhou S, Lo WC, Suhalim JL, Digman MA, Gratton E, Nie Q, Lander AD.
    Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc.
    Curr Biol. 2012; 22(8): 668-675. PMCID: PMC3338872
  25. Kniazeva E, Weidling JW, Singh R, Botvinick EL, Digman MA, Gratton E, Putnam AJ.
    Quantification of local matrix deformations and mechanical properties during capillary morphogenesis in 3D.
    Integr Biol (Camb). 2012; 4(4): 431-439. PMCID: PMC3771856
  26. Meng L, Mantulin WW, Alexander BS, Cerussi AE, Tromberg BJ, Yu Z, Laning K, Kain ZN, Cannesson M, Gelb AW.
    Head-up tilt and hyperventilation produce similar changes in cerebral oxygenation and blood volume: an observational comparison study using frequency-domain near-infrared spectroscopy.
    Can J Anaesth. 2012; 59(4): 357-365. PMCID: PMC3371769
  27. Estrada LC Gratton E.
    Spectroscopic properties of gold nanoparticles at the single-particle level in biological environments.
    Chemphyschem. 2012; 13(4): 1087-1092. PMCID: PMC4245151
  28. Hinde E, Digman MA, Welch C, Hahn KM, Gratton E.
    Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy.
    Microsc Res Tech. 2012; 75(3): 271-281. PMCID: PMC3523109
  29. Hinde E, Cardarelli F, Digman MA, Gratton E.
    Changes in chromatin compaction during the cell cycle revealed by micrometer-scale measurement of molecular flow in the nucleus.
    Biophys J. 2012; 102(3): 691-697. PMCID: PMC3274830

2011

  1. Sánchez SA, Gratton E, Zanocco AL, Lemp E, Gunther G.
    Sucrose monoester micelles size determined by Fluorescence Correlation Spectroscopy (FCS).
    PLoS One. 2011; 6(12): e29278. PMCID: PMC3247245
  2. Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU.
    Tandem SAM domain structure of human Caskin1: A presynaptic, self-assembling scaffold for CASK.
    Structure. 2011; 19(12): 1826-1836. PMCID: PMC3240820
  3. Estrada LC Gratton E.
    3D nanometer images of biological fibers by directed motion of gold nanoparticles.
    Nano Lett. 2011; 11(11): 4656-4660. PMCID: PMC3220937
  4. Leproux A, Cerussi AE, Tanamai VW, Durkin AF, Compton M, Tromberg BJ, Gratton E.
    Impact of contralateral and ipsilateral reference tissue selection on self-referencing differential spectroscopy for breast cancer detection.
    J Biomed Opt. 2011; 16(11): 116019. PMCID: PMC3223514
  5. Lanzanò L, Lei T, Okamura K, Giral H, Caldas YA, Masihzadeh O, Gratton E, Levi M, Blaine J.
    Differential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid hormone.
    Am J Physiol Cell Physiol. 2011; 301(4): C850-861. PMCID: PMC3191571
  6. Labeed FH, Lu J, Mulhall HJ, Marchenko SA, Hoettges KF, Estrada LC, Lee AP, Hughes MP, Flanagan LA.
    Biophysical characteristics reveal neural stem cell differentiation potential.
    PLoS One. 2011; 6(9): e25458. PMCID: PMC3184132
  7. Crosignani V, Dvornikov AS, Gratton E.
    Enhancement of imaging depth in turbid media using a wide area detector.
    J Biophotonics. 2011; 4(9): 592-599. PMCID: PMC4245154
  8. Santoro Y, Leproux A, Cerussi AE, Tromberg BJ, Gratton E.
    Breast cancer spatial heterogeneity in near-infrared spectra and the prediction of neoadjuvant chemotherapy response.
    J Biomed Opt. 2011; 16(9): 097007. PMCID: PMC3203125
  9. Hinde E Cardarelli F.
    Measuring the flow of molecules in cells.
    Biophys Rev. 2011; 3(3): 119-129.
  10. Wolf U, Toronov VY, Choi JH, Gupta R, Michalos A, Gratton E, Wolf M.
    Correlation of functional and resting state connectivity of cerebral oxy-, deoxy-, and total hemoglobin concentration changes measured by near-infrared spectrophotometry.
    J Biomed Opt. 2011; 16(8): 087013. PMCID: PMC3170400
  11. Cardarelli F, Lanzanò L, Gratton E.
    Fluorescence correlation spectroscopy of intact nuclear pore complexes.
    Biophys J. 2011; 101(4): L27-29. PMCID: PMC3175086
  12. Stringari C, Cinquin A, Cinquin O, Digman MA, Donovan PJ, Gratton E.
    Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue.
    Proc Natl Acad Sci USA. 2011; 108(33): 13582-13587. PMCID: PMC3158156
  13. Marchini C, Pozzi D, Montani M, Alfonsi C, Amici A, de Sanctis SC, Digman MA, Sánchez SA, Gratton E, Amenitsch H, Fabbretti A, Gualerzi CO, Caracciolo G.
    Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes.
    Cancer Gene Ther. 2011; 18(8): 543-552. PMCID: PMC3940159
  14. Ramella NA, Rimoldi OJ, Prieto ED, Schinella GR, Sánchez SA, Jaureguiberry MS, Vela ME, Ferreira ST, Tricerri MA.
    Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis.
    PLoS One. 2011; 6(7): e22532. PMCID: PMC3139661
  15. Sánchez SA, Bakás L, Gratton E, Herlax V.
    Alpha Hemolysin induces an increase of Erythrocytes Calcium: A FLIM 2-photon phasor analysis approach.
    PLoS One. 2011; 6(6): e21127. PMCID: PMC3116868
  16. Itano MS, Neumann AK, Liu P, Zhang F, Gratton E, Parak WJ, Thompson NL, Jacobson KA.
    DC-SIGN and influenza Hemagglutinin dynamics in plasma membrane microdomains are markedly different.
    Biophys J. 2011; 100(11): 2662-2670. PMCID: PMC3117154
  17. Meng L, Cannesson M, Alexander BS, Yu Z, Kain ZN, Cerussi AE, Tromberg BJ, Mantulin WW.
    Effect of phenylephrine and ephedrine bolus treatment on cerebral oxygenation in anaesthetized patients.
    Br J Anaesth. 2011; 107(2): 209-217. PMCID: PMC3136202
  18. Lanzanò L, Digman MA, Fwu P, Giral H, Levi M, Gratton E.
    Nanometer-scale imaging by the modulation tracking method.
    J Biophotonics. 2011; 4(6): 415-424. PMCID: PMC3393040
  19. Kotlarchyk MA, Shreim SG, Alvarez-Elizondo MB, Estrada LC, Singh R, Valdevit L, Kniazeva E, Gratton E, Putnam AJ, Botvinick EL.
    Concentration independent modulation of local micromechanics in a fibrin gel.
    PLoS One. 2011; 6(5): e20201. PMCID: PMC3100350
  20. Caracciolo G, Pozzi D, Capriotti AL, Marianecci C, Carafa M, Marchini C, Montani M, Amici A, Amenitsch H, Digman MA, Gratton E, Sánchez SA, Laganà A.
    Factors determining the superior performance of lipid/DNA/protammine nanoparticles over lipoplexes.
    J Med Chem. 2011; 54(12): 4160-4171.
  21. Digman MA Gratton E.
    Lessons in fluctuation correlation spectroscopy.
    Ann Rev Phys Chem. 2011; 62: 645-668. PMCID: PMC3576135
  22. Sánchez SA, Gunther G, Tricerri MA, Gratton E.
    Methyl-β-Cyclodextrins preferentially remove cholesterol from the liquid disordered phase in giant unilamellar vesicles.
    J Membr Biol. 2011; 241(1): 1-10. PMCID: PMC3082695
  23. Giral H, Lanzanò L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M.
    Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters.
    J Biol Chem. 2011; 286(17): 15032-15042. PMCID: PMC3083164
  24. Hinde E, Cardarelli F, Digman MA, Kershner A, Kimble J, Gratton E.
    The impact of mitotic versus interphase chromatin architecture on the molecular flow of EGFP by pair correlation analysis.
    Biophys J. 2011; 100(7): 1829-1836. PMCID: PMC3072664
  25. Moens PDJ, Gratton E, Salvemini IL.
    Fluorescence correlation spectroscopy, raster image correlation spectroscopy, and number and brightness on a commercial confocal laser scanning microscope with analog detectors (Nikon C1).
    Microsc Res Tech. 2011; 74(4): 377-388. PMCID: PMC3001136
  26. Azartash K, Kwan JT, Paugh JR, Nguyen AL, Jester JV, Gratton E.
    Pre-corneal tear film thickness in humans measured with a novel technique.
    Mol Vis. 2011; 17: 756-767. PMCID: PMC3081798
  27. Blaine J, Lanzanò L, Girala H, Caldasa Y, Levia M, Grattona E, Moldovana R, Lei T.
    Dynamic imaging of the sodium phosphate cotransporters.
    Adv Chronic Kidney Dis. 2011; 18(2): 145-150. PMCID: PMC3220941
  28. Behne MJ, Sánchez SA, Barry NP, Kirschner N, Meyer W, Mauro TM, Moll I, Gratton E.
    Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis.
    Arch Dermatol Res. 2011; 303(2): 103-115. PMCID: PMC4548958
  29. Gratton E.
    Deeper tissue imaging with total detection.
    Science. 2011; 331(6020): 1016-1017.
  30. Chen B, Estrada LC, Hellriegel C, Gratton E.
    Nanometer-scale optical imaging of collagen fibers using gold nanoparticles.
    Biomed Opt Express. 2011; 2(3): 511-519. PMCID: PMC3047357
  31. Ross JA, Digman MA, Wang L, Gratton E, Albanesi JP, Jameson DM.
    Oligomerization state of Dynamin 2 in cell membranes using TIRF and number and brightness analysis.
    Biophys J. 2011; 100(3): L15-17. PMCID: PMC3030261
  32. Choi CK, Zareno J, Digman MA, Gratton E, Horwitz AR.
    Cross-correlated fluctuation analysis reveals phosphorylation-regulated Paxillin-FAK complexes in nascent adhesions.
    Biophys J. 2011; 100(3): 583-592. PMCID: PMC3030238
  33. Vetri V, Ossato G, Militello V, Digman MA, Leone M, Gratton E.
    Fluctuation methods to study protein aggregation in live cells: Concanavalin A oligomers formation.
    Biophys J. 2011; 100(3): 774-783. PMCID: PMC3030242

2010

  1. Kim SA, Sanabria H, Digman MA, Gratton E, Schwille P, Zipfel WR, Waxham MN.
    Quantifying translational mobility in neurons: comparison between current optical techniques.
    J Neurosci. 2010; 30(49): 16409-16416. PMCID: PMC3003925
  2. Kuo Wj, Digman MA, Lander AD.
    Heparan sulfate acts as a BMP co-receptor by facilitating ligand-induced receptor hetero-oligomerization.
    Mol Biol Cell. 2010; 21(22): 4028-4041. PMCID: PMC2982130
  3. Fu CC, Ossato G, Long M, Digman MA, Gopinathan A, Lee LP, Gratton E, Khine M.
    Bimetallic nanopetals for thousand-fold fluorescence enhancements.
    Appl Phys Lett. 2010; 97(20): 203101.
  4. Sánchez SA.
    Book Review: Handbook of Biomedical Nonlinear Optical Microscopy. B R Masters and P T C So. Oxford University Press, 2008.
    Microsc Microanal. 2010; 16(6): 842.
  5. Azartash K, Shy CjN, Flynn K, Jester JV, Gratton E.
    Non-invasive in vivo measurement of the tear film using spatial autocorrelation in a live mammal model.
    Biomed Opt Express. 2010; 1(4): 1127-1137. PMCID: PMC3018089
  6. Rossow MJ, Sasaki JM, Digman MA, Gratton E.
    Raster image correlation spectroscopy in live cells.
    Nat Protoc. 2010; 5(11): 1761-1774. PMCID: PMC3089972
  7. Presman DM, Alvarez LD, Levi V, Eduardo S, Digman MA, Martí MA, Veleiro AS, Burton G, Pecci A.
    Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.
    PLoS One. 2010; 5(10): e13279. PMCID: PMC2952596
  8. Hinde E, Cardarelli F, Digman MA, Gratton E.
    In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependent molecular flow.
    Proc Natl Acad Sci USA. 2010; 107(38): 16560-16565. PMCID: PMC2944750
  9. Celli A Gratton E.
    Dynamics of lipid domain formation: fluctuation analysis.
    Biochim Biophys Acta. 2010; 1798(7): 1368-1376. PMCID: PMC2883005
  10. Sánchez SA, Tricerri MA, Ossato G, Gratton E.
    Lipid packing determines protein-membrane interactions: challenges for apolipoprotein A-I and high density lipoproteins.
    Biochim Biophys Acta. 2010; 1798(7): 1399-1408. PMCID: PMC2883020
  11. Lim RS, Kratzer A, Barry NP, Miyazaki-Anzai S, Miyazaki M, Mantulin WW, Levi M, Potma EO, Tromberg BJ.
    Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice.
    J Lipid Res. 2010; 51(7): 1729-37. PMCID: PMC2882730
  12. Ossato G, Digman MA, Aiken C, Lukacsovich T, Marsh JL, Gratton E.
    A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis.
    Biophys J. 2010; 98(12): 3078-3085. PMCID: PMC2884247
  13. Cardarelli F Gratton E.
    In vivo imaging of single-molecule translocation through nuclear pore complexes by pair correlation functions.
    PLoS One. 2010; 5(5): e10475. PMCID: PMC2862743
  14. Rossow MJ, Mantulin WW, Gratton E.
    Scanning laser image correlation for measurement of flow.
    J Biomed Opt. 2010; 15(2): 026003. PMCID: PMC2869368
  15. Jaureguiberry MS, Tricerri MA, Sánchez SA, Garda HA, Finarelli GS, Gonzalez MC, Rimoldi OJ.
    Membrane organization and regulation of cellular Cholesterol homeostasis.
    J Membr Biol. 2010; 234(3): 183-194. PMCID: PMC2868589
  16. Celli A, Sánchez SA, Behne MJ, Hazlett TL, Gratton E, Mauro TM.
    The epidermal Ca(2+) gradient: measurement using the phasor representation of fluorescent lifetime imaging.
    Biophys J. 2010; 98(5): 911-921. PMCID: PMC2830439
  17. Yoon Y, Tong J, Lee PJ, Albanese A, Bhardwaj N, Källberg M, Digman MA, Lu H, Gratton E, Shin YK, Cho W.
    Molecular basis of the potent membrane remodeling activity of the epsin1 ENTH domain.
    J Biol Chem. 2010; 285(1): 531-540. PMCID: PMC2804201
  18. Kukreti S, Cerussi AE, Tanamai W, Hsiang D, Tromberg BJ, Gratton E.
    Characterization of metabolic differences between benign and malignant tumors: high-spectral-resolution diffuse optical spectroscopy.
    Radiology. 2010; 254(1): 277-284. PMCID: PMC2797652

2009

  1. Tanner K, Ferris DR, Lanzanò L, Mandefro B, Mantulin WW, Gardiner DM, Rugg EL, Gratton E.
    Coherent movement of cell layers during wound healing by image correlation spectroscopy.
    Biophys J. 2009; 97(7): 2098-2106. PMCID: PMC2756390
  2. Katayama Y, Burkacky O, Meyer M, Bräuchle C, Gratton E, Lamb DC.
    Real-time nanomicroscopy via three-dimensional single-particle tracking.
    ChemPhysChem. 2009; 10(14): 2458-2464. PMCID: PMC2857558
  3. Digman MA Gratton E.
    Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy, applications in systems biology.
    WIREs Syst Biol Med. 2009; 1(2): 273-282. PMCID: PMC3086279
  4. Portolés MJL, Nieto FR, Soria DB, Amalvy JI, Peruzzo PJ, Mártire DO, Kotler M, Holub O, Gonzalez MC.
    Photophysical properties of blue-emitting silicon nanoparticles.
    J Phys Chem C. 2009; 113(31): 13694-13702. PMCID: PMC3410643
  5. Digman MA Gratton E.
    Imaging barriers to diffusion by pair correlation functions.
    Biophys J. 2009; 97(2): 665-673. PMCID: PMC2711318
  6. Krishnan K, Holub O, Gratton E, Clayton AHA, Cody S, Moens PDJ.
    Profilin interaction with phosphatidylinositol (4,5)-bisphosphate destabilizes the membrane of giant unilamellar vesicles.
    Biophys J. 2009; 96(12): 5112-5121. PMCID: PMC2712054
  7. Gielen E, Smisdom N, vandeVen MJ, de Clercq B, Gratton E, Digman MA, Rigo JM, Hofkens J, Engelborghs Y, Ameloot M.
    Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): use of a commercial laser-scanning microscope with analog detection.
    Langmuir. 2009; 25(9): 5209-5218. PMCID: PMC2728053
  8. Henning MF, Sánchez SA, Bakás L.
    Visualization and analysis of lipopolysaccharide distribution in binary phospholipid bilayers.
    Biochem Biophys Res Commun. 2009; 383(1): 22-26. PMCID: PMC2865696
  9. Caracciolo G, Digman MA, Gratton E, Sánchez SA, Caminiti R.
    Efficient escape from endosomes determines the superior efficiency of multicomponent lipoplexes.
    J Phys Chem B. 2009; 113(15): 4995-4997. PMCID: PMC2673460
  10. Digman MA Gratton E.
    Analysis of diffusion and binding in cells using the RICS approach.
    Microsc Res Tech. 2009; 72(4): 323-332. PMCID: PMC4364519
  11. Tyler KM, Fridberg A, Toriello KM, Olson CL, Cieslak JA, Hazlett TL, Engman DM.
    Flagellar membrane localization via association with lipid rafts.
    J Cell Sci. 2009; 122(Pt 6): 859-866. PMCID: PMC2714428
  12. Rossow MJ, Mantulin WW, Gratton E.
    Spatiotemporal image correlation spectroscopy measurements of flow demonstrated in microfluidic channels.
    J Biomed Opt. 2009; 14(2): 024014. PMCID: PMC2702990
  13. Digman MA, Wiseman PW, Choi CK, Horwitz AR, Gratton E.
    Stoichiometry of molecular complexes at adhesions in living cells.
    Proc Natl Acad Sci USA. 2009; 106(7): 2170-2175. PMCID: PMC2630200
  14. Gratton E Digman MA.
    One photon up, one photon down.
    Nat Biotechnol. 2009; 27(2): 147-148.
  15. Toro CA, Sánchez SA, Zanocco A, Lemp E, Gratton E, Gunther G.
    Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size.
    Chem Phys Lipids. 2009; 157(2): 104-112. PMCID: PMC2868593
  16. Digman MA, Wiseman PW, Horwitz AR, Gratton E.
    Detecting protein complexes in living cells from laser scanning confocal image sequences by the cross correlation raster image spectroscopy method.
    Biophys J. 2009; 96(2): 707-716. PMCID: PMC2716688

2008

  1. Kukreti S, Cerussi AE, Tromberg BJ, Gratton E.
    Intrinsic near-infrared spectroscopic markers of breast tumors.
    Dis Markers. 2008; 25(6): 281-290. PMCID: PMC2732199
  2. Sanabria H, Digman MA, Gratton E, Waxham MN.
    Spatial diffusivity and availability of intracellular Calmodulin.
    Biophys J. 2008; 95(12): 6002-6015. PMCID: PMC2599858
  3. Watson NB, Nelson E, Digman MA, Thornburg JA, Alphenaar BW, McGregor WG.
    RAD18 and associated proteins are immobilized in nuclear foci in human cells entering S-phase with ultraviolet light-induced damage.
    Mutat Res. 2008; 648(1-2): 23-31. PMCID: PMC2610409
  4. Unruh JR Gratton E.
    Analysis of molecular concentration and brightness from fluorescence fluctuation data with an electron multiplied CCD camera.
    Biophys J. 2008; 95(11): 5385-5398. PMCID: PMC2586556
  5. Barreiro O, Zamai M, Yáñez-Mó M, Tejera E, López-Romero P, Monk PN, Gratton E, Caiolfa VR, Sánchez-Madrid F.
    Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms.
    J Cell Biol. 2008; 183(3): 527-542. PMCID: PMC2575792
  6. Fratoddi I, Gohlke C, Cametti C, Diociaiuti M, Russo MV.
    Self-assembly of nanostructured polymetallaynes.
    Polymer. 2008; 49(15): 3211-3216.
  7. Malengo G, Andolfo A, Sidenius N, Gratton E, Zamai M, Caiolfa VR.
    Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor.
    J Biomed Opt. 2008; 13(3): 031215. PMCID: PMC2718687
  8. Levi V Gratton E.
    Chromatin dynamics during interphase explored by single-particle tracking.
    Chromosome Res. 2008; 16(3): 439-449. PMCID: PMC2701671
  9. Kwok S, Lee CY, Sánchez SA, Hazlett TL, Gratton E, Hayashi Y.
    Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity.
    Biochem Biophys Res Comm. 2008; 369(2): 519-525. PMCID: PMC2396457
  10. Digman MA, Brown CM, Horwitz AR, Mantulin WW, Gratton E.
    Paxillin dynamics measured during adhesion assembly and disassembly by correlation spectroscopy.
    Biophys J. 2008; 94(7): 2819-2831. PMCID: PMC2267137
  11. Garcia-Marcos A, Sánchez SA, Parada P, Eid JS, Jameson DM, Remacha M, Gratton E, Ballesta JPG.
    Yeast ribosomal stalk heterogeneity in vivo shown by two-photon FCS and molecular brightness analysis.
    Biophys J. 2008; 94(7): 2884-2890. PMCID: PMC2267128
  12. Digman MA, Dalal RB, Horwitz AR, Gratton E.
    Mapping the number of molecules and brightness in the laser scanning microscope.
    Biophys J. 2008; 94(6): 2320-2332. PMCID: PMC2257897
  13. Raub CB, Unruh JR, Suresh V, Krasieva TB, Lindmo T, Gratton E, Tromberg BJ, George SC.
    Image correlation spectroscopy of multiphoton images correlates with collagen mechanical properties.
    Biophys J. 2008; 94(6): 2361-2373. PMCID: PMC2257909
  14. Colyer RA, Lee CY, Gratton E.
    A novel fluorescence lifetime imaging system that optimizes photon efficiency.
    Microsc Res Tech. 2008; 71(3): 201-213.
  15. Sánchez SA, Tricerri MA, Gratton E.
    Detecting cholesterol changes in lipid bilayers.
    BioWorld Europe. 2008; 1: 8-11.
  16. Digman MA, Caiolfa VR, Zamai M, Gratton E.
    The Phasor approach to fluorescence lifetime imaging analysis.
    Biophys J. 2008; 94(2): L14-16. PMCID: PMC2157251
  17. Fiorini R, Ragni L, Ambrosi S, Littarru GP, Gratton E, Hazlett TL.
    Fluorescence studies of the interactions of ubiquinol-10 with liposomes.
    Photochem Photobiol. 2008; 84(1): 209-214.
  18. Dalal RB, Digman MA, Horwitz AR, Vetri V, Gratton E.
    Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode.
    Microsc Res Tech. 2008; 71(1): 69-81.
  19. Celli A, Beretta S, Gratton E.
    Phase fluctuations on the micron-submicron scale in GUVs composed of a binary lipid mixture.
    Biophys J. 2008; 94(1): 104-116. PMCID: PMC2134868
  20. Brown CM, Dalal RB, Hebert B, Digman MA, Horwitz AR, Gratton E.
    Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope.
    J Microsc. 2008; 229(1): 78-91. PMCID: PMC3690660

2007

  1. Caiolfa VR, Zamai M, Malengo G, Andolfo A, Madsen CD, Sutin JDB, Digman MA, Gratton E, Blasi F, Sidenius N.
    Monomer–dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies.
    J Cell Biol. 2007; 179(5): 1067-1082. PMCID: PMC2099195
  2. Olopade CO, Mensah E, Gupta R, Huo D, Picchiett DL, Gratton E, Michalos A.
    Noninvasive determination of brain tissue oxygenation during sleep in obstructive sleep apnea: a near-infrared spectroscopic approach.
    Sleep. 2007; 30(12): 1747-1755. PMCID: PMC2276122
  3. Wolf U, Wolf M, Choi JH, Paunescu LA, Michalos A, Gratton E.
    Regional differences of hemodynamics and oxygenation in the human calf muscle detected with near-infrared spectrophotometry.
    J Vasc Interv Radiol. 2007; 18(9): 1094-1101.
  4. Gatto R, Hoffman W, Paisansathan C, Mantulin WW, Gratton E, Charbel FT.
    Effect of age on brain oxygenation regulation during changes in position.
    J Neurosci Methods. 2007; 164(2): 308-311.
  5. Sánchez SA, Tricerri MA, Gratton E.
    Interaction of high density lipoprotein particles with membranes containing cholesterol.
    J Lipid Res. 2007; 48(8): 1689-1700.
  6. Levi V Gratton E.
    Exploring dynamics in living cells by tracking single particles.
    Cell Biochem Biophys. 2007; 48(1): 1-15.
  7. Ermolenko DN, Spiegel PC, Majumdar ZK, Hickerson RP, Clegg RM, Noller HF.
    The antibiotic viomycin traps the ribosome in an intermediate state of translocation.
    Nat Struct Mol Biol. 2007; 14: 493-497.
  8. Holub O, Seufferheld MJ, Gohlke C, Govindjee, Heiss GJ, Clegg RM.
    Fluorescence lifetime imaging microscopy of chlamydomonas reinhardtii: non-photochemical quenching mutants and the effect of photosynthetic inhibitors on the slow chlorophyll fluorescence transient.
    J Microsc. 2007; 226(2): 90-120.
  9. Ermolenko DN, Majumdar ZK, Hickerson RP, Spiegel PC, Clegg RM, Noller HF.
    Observation of intersubunit movement of the ribosome in solution using FRET.
    J Mol Biol. 2007; 370(3): 530-540.
  10. Kukreti S, Cerussi AE, Tromberg BJ, Gratton E.
    Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra.
    J Biomed Opt. 2007; 12(2): 020509.
  11. Boens N, Qin W, Basari N, Hofkens J, Ameloot M, Pouget J, Lefèvre JP, Valeur B, Gratton E, vandeVen MJ, Silva N Jr, Engelborghs Y, Willaert K, Sillen A, Rumbles G, Phillips D, Visser AJWG, van Hoek A, Lakowicz JR, Malak H, Gryczynski I, Szabo AG, Krajcarski DT, Tamai N, Miura A.
    Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy.
    Anal Chem. 2007; 79(5): 2137-49.
  12. Calderon-Arnulphi M, Alaraj AM, Amin-Hanjani S, Mantulin WW, Polzonetti CM, Gratton E, Charbel FT.
    Detection of cerebral ischemia in neurovascular surgery using quantitative frequency-domain near-infrared spectroscopy.
    J Neurosurg. 2007; 106(2): 283-290.
  13. Tanner K, Beitel E, D'Amico E, Mantulin WW, Gratton E.
    Effects of vasodilation on intrinsic optical signals in the mammalian brain: a phantom study.
    J Biomed Opt. 2007; 11(6): 064020.

2006

  1. Hanson KM, Gratton E, Bardeen CJ.
    Sunscreen enhancement of UV-induced reactive oxygen species in the skin.
    Free Radic Biol Med. 2006; 41(8): 1205-12.
  2. Nicolini C, Celli A, Gratton E, Winter R.
    Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study.
    Biophys J. 2006; 91(8): 2936-42. PMCID: PMC1578477
  3. Eckhoff DA, Stuart JN, Sutin JDB, Sweedler JV, Gratton E.
    Capillary electrophoresis of ultrasmall carboxylate functionalized silicon nanoparticles.
    J Chem Phys. 2006; 125(8): 081103.
  4. Ragan TM, Huang H, So PTC, Gratton E.
    3D particle tracking on a two-photon microscope.
    J Fluoresc. 2006; 16(3): 325-36.
  5. Lee NY, Hazlett TL, Koland JG.
    Structure and dynamics of the epidermal growth factor receptor C-terminal phosphorylation domain.
    Protein Sci. 2006; 15(5): 1142-52. PMCID: PMC2242510
  6. Rogozhina EV, Eckhoff DA, Gratton E, Braun PV.
    Carboxyl functionalization of ultrasmall luminescent silicon nanoparticles through thermal hydrosilylation.
    J Mater Chem. 2006; 16: 1421-1430.
  7. Nicolini C, Baranski J, Schlummer S, Palomo J, Lumbierres-Burgues M, Kahms M, Kuhlmann J, Sánchez SA, Gratton E, Waldmann H, Winter R.
    Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption.
    J Am Chem Soc. 2006; 128(1): 192-201.
  8. Simonson PD, D'Amico E, Gratton E.
    Modulation of an optical needle's reflectivity alters the average photon path through scattering media.
    J Biomed Opt. 2006; 11(1): 014023.
  9. Levi V, Gelfand VI, Serpinskaya AS, Gratton E.
    Melanosomes transported by myosin-V in Xenopus melanophores perform slow 35 nm steps.
    Biophys J. 2006; 90(1): L07-9. PMCID: PMC1367043
  10. Levi V, Serpinskaya AS, Gratton E, Gelfand VI.
    Organelle transport along microtubules in Xenopus melanophores: evidence for cooperation between multiple motors.
    Biophys J. 2006; 90(1): 318-27. PMCID: PMC1367030

2005

  1. Gokhale NA, Abraham A, Digman MA, Gratton E, Cho W.
    Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer.
    J Biol Chem. 2005; 280(52): 42831-40.
  2. Redford GI, Majumdar ZK, Sutin JDB, Clegg RM.
    Properties of microfluidic turbulent mixing revealed by fluorescence lifetime imaging.
    J Chem Phys. 2005; 123(22): 224504.
  3. Levi V, Ruan Q, Plutz M, Belmont AS, Gratton E.
    Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope.
    Biophys J. 2005; 89(6): 4275-85. PMCID: PMC1366992
  4. Majumdar ZK, Sutin JDB, Clegg RM.
    Microfabricated continuous-flow, turbulent, microsecond mixer.
    Rev Sci Instrum. 2005; 76(12): 125103.
  5. Hickerson RP, Majumdar ZK, Baucom A, Clegg RM, Noller HF.
    Measurement of internal movements within the 30 S ribosomal subunit using Förster resonance energy transfer.
    J Mol Biol. 2005; 354(2): 459-72.
  6. Tanner K, D'Amico E, Kaczmarowski A, Kukreti S, Malpeli JG, Mantulin WW, Gratton E.
    Spectrally resolved neurophotonics: a case report of hemodynamics and vascular components in the mammalian brain.
    J Biomed Opt. 2005; 10(6): 064009.
  7. Eckhoff DA, Sutin JDB, Clegg RM, Gratton E, Rogozhina EV, Braun PV.
    Optical characterization of ultrasmall Si nanoparticles prepared through electrochemical dispersion of bulk Si.
    J Phys Chem B. 2005; 109(42): 19786-97.
  8. Majumdar ZK, Hickerson RP, Noller HF, Clegg RM.
    Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: quantitative spectroscopic methods.
    J Mol Biol. 2005; 351(5): 1123-45.
  9. Redford GI Clegg RM.
    Polar plot representation for frequency-domain analysis of fluorescence lifetimes.
    J Fluoresc. 2005; 15(5): 805-15.
  10. Digman MA, Brown CM, Sengupta P, Wiseman PW, Horwitz AR, Gratton E.
    Measuring fast dynamics in solutions and cells with a laser scanning microscope.
    Biophys J. 2005; 89(2): 1317-27. PMCID: PMC1366616
  11. Arnulphi C, Sánchez SA, Tricerri MA, Gratton E, Jonas A.
    Interaction of human apolipoprotein A-I with model membranes exhibiting lipid domains.
    Biophys J. 2005; 89(1): 285-95. PMCID: PMC1366526
  12. Sánchez SA Gratton E.
    Lipid-protein interactions revealed by two-photon microscopy and fluorescence correlation spectroscopy.
    Acc Chem Res. 2005; 38(6): 469-77.
  13. Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Melowic HR, Rafter JD, Cho W.
    Diacylglycerol-induced membrane targeting and activation of protein kinase Cε. Mechanistic differences between protein kinases Cδ and Cε.
    J Biol Chem. 2005; 280(20): 19784-19793.
  14. Digman MA, Sengupta P, Wiseman PW, Brown CM, Horwitz AR, Gratton E.
    Fluctuation correlation spectroscopy with a laser-scanning microscope: exploiting the hidden time structure.
    Biophys J. 2005; 88(5): L33-6. PMCID: PMC1305524
  15. Tricerri MA, Toledo JD, Sánchez SA, Hazlett TL, Gratton E, Jonas A, Garda HA.
    Visualization and analysis of apolipoprotein A-I interaction with binary phospholipid bilayers.
    J Lipid Res. 2005; 46(4): 669-78.
  16. Levi V, Ruan Q, Gratton E.
    3-D particle tracking in a two-photon microscope: application to the study of molecular dynamics in cells.
    Biophys J. 2005; 88(4): 2919-28. PMCID: PMC1305386
  17. Gratton E, Toronov VY, Wolf U, Wolf M, Webb A.
    Measurement of brain activity by near-infrared light.
    J Biomed Opt. 2005; 10(1): 11008.

2004

  1. Inoue M, Digman MA, Cheng MA, Breusegem SY, Halaihel N, Sorribas V, Mantulin WW, Gratton E, Barry NP, Levi M.
    Partitioning of NaPi cotransporter in cholesterol-, sphingomyelin-, and glycosphingolipid-enriched membrane domains modulates NaPi protein diffusion, clustering, and activity.
    J Biol Chem. 2004; 279(47): 49160-71.
  2. Barcellona ML, Gammon S, Hazlett TL, Digman MA, Gratton E.
    Polarized fluorescence correlation spectroscopy of DNA-DAPI complexes.
    Microsc Res Tech. 2004; 65(4-5): 205-17.
  3. Masters BR, So PTC, Buehler C, Barry NP, Sutin JDB, Mantulin WW, Gratton E.
    Mitigating thermal mechanical damage potential during two-photon dermal imaging.
    J Biomed Opt. 2004; 9(6): 1265-70.
  4. Safonova LP, Michalos A, Wolf U, Wolf M, Hueber DM, Choi JH, Gupta R, Polzonetti CM, Mantulin WW, Gratton E.
    Age-correlated changes in cerebral hemodynamics assessed by near-infrared spectroscopy.
    Arch Gerontol Geriatr. 2004; 39(3): 207-25.
  5. Hart AJ, Slocum AH, Sutin JDB.
    Segmented and shielded structures for reduction of thermal expansion-induced tilt errors.
    Precision Eng. 2004; 28(4): 443-458.
  6. Czeslik C, Jackler G, Hazlett TL, Gratton E, Steitz R, Wittemann A, Ballauff M.
    Salt-induced protein resistance of polyelectrolyte brushes studied using fluorescence correlation spectroscopy and neutron reflectometry.
    Phys Chem Chem Phys. 2004; 6: 5557-5563.
  7. Ruan Q, Cheng MA, Levi M, Gratton E, Mantulin WW.
    Spatial-temporal studies of membrane dynamics: scanning fluorescence correlation spectroscopy (SFCS).
    Biophys J. 2004; 87(2): 1260-7. PMCID: PMC1304464
  8. Janosch S, Nicolini C, Ludolph B, Peters C, Völkert M, Hazlett TL, Gratton E, Waldmann H, Winter R.
    Partitioning of dual-lipidated peptides into membrane microdomains: lipid sorting vs peptide aggregation.
    J Am Chem Soc. 2004; 126(24): 7496-503.
  9. Borovikov YS, Dedova IV, Remedios CGd, Vikhoreva NN, Vikhorev PG, Avrova SV, Hazlett TL, van der Meer BW.
    Fluorescence depolarization of actin filaments in reconstructed myofibers: the effect of S1 or pPDM-S1 on movements of distinct areas of actin.
    Biophys J. 2004; 86(5): 3020-9. PMCID: PMC1304168
  10. Rao S, Sutin JDB, Clegg RM, Gratton E, Nayfeh MH, Habbal S, Tsolakidis A, Martin RM.
    Excited states of tetrahedral single-core Si29 nanoparticles.
    Phys Rev B. 2004; 69(20): 205319.
  11. Hohng S, Wilson TJ, Tan E, Clegg RM, Lilley DMJ, Ha T.
    Conformational flexibility of four-way junctions in RNA.
    J Mol Biol. 2004; 336(1): 69-79.
  12. Czeslik C, Jansen RP, Ballauff M, Wittemann A, Royer CA, Gratton E, Hazlett TL.
    Mechanism of protein binding to spherical polyelectrolyte brushes studied in situ using two-photon excitation fluorescence fluctuation spectroscopy.
    Phys Rev E. 2004; 69(2): 021401.
  13. Lee EH, Faulhaber D, Hanson KM, Ding W, Peters S, Kodali S, Granstein RD.
    Dietary Lutein reduces ultraviolet radiation-induced inflammation and immunosuppression.
    J Invest Dermatol. 2004; 122(2): 510-517.
  14. Clegg RM.
    The vital contributions of Perrin and Förster.
    Biophotonics Int. 2004; 11(9): 42-45.
  15. Choi JH, Wolf M, Toronov VY, Wolf U, Polzonetti CM, Hueber DM, Safonova LP, Gupta R, Michalos A, Mantulin WW, Gratton E.
    Noninvasive determination of the optical properties of adult brain: near-infrared spectroscopy approach.
    J Biomed Opt. 2004; 9(1): 221-9.
  16. Kis-Petiková K Gratton E.
    Distance measurement by circular scanning of the excitation beam in the two-photon microscope.
    Microsc Res Tech. 2004; 63(1): 34-49.
  17. Dedova IV, Avrova SV, Vikhoreva NN, Vikhorev PG, Hazlett TL, van der Meer BW, Remedios CGd, Borovikov YS.
    Conformational changes of actin induced by strong or weak myosin subfragment-1 binding.
    Tsitologiia. 2004; 46(8): 719-34.
  18. Sánchez SA, Brunet JE, Jameson DM, Lagos R, Monasterio O.
    Tubulin equilibrium unfolding followed by time-resolved fluorescence and fluorescence correlation spectroscopy.
    Protein Sci. 2004; 13(1): 81-88. PMCID: PMC2286518
  19. Morren G, Wolf U, Lemmerling P, Wolf M, Choi JH, Gratton E, de Lathauwer L, van Huffel S.
    Detection of fast neuronal signals in the motor cortex from functional near infrared spectroscopy measurements using independent component analysis.
    Med Biol Eng Comput. 2004; 42(1): 92-99.

2003

  1. Gaus K, Gratton E, Kable EPW, Jones AS, Gelissen I, Kritharides L, Jessup W.
    Visualizing lipid structure and raft domains in living cells with two-photon microscopy.
    Proc Natl Acad Sci USA. 2003; 100(26): 15554-9. PMCID: PMC307606
  2. Hanson KM Clegg RM.
    Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species.
    J Cosmet Sci. 2003; 54(5): 589-98.
  3. Toronov VY, D'Amico E, Hueber DM, Gratton E, Barbieri BB, Webb A.
    Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain.
    Opt Express. 2003; 11(21): 2717-2729.
  4. Müller JD Gratton E.
    High-pressure fluorescence correlation spectroscopy.
    Biophys J. 2003; 85(4): 2711-9. PMCID: PMC1303495
  5. Campanini B, Raboni S, Vaccari S, Zhang L, Cook PF, Hazlett TL, Mozzarelli A, Bettati S.
    Surface-exposed tryptophan residues are essential for O-acetylserine sulfhydrylase structure, function, and stability.
    J Biol Chem. 2003; 278(39): 37511-9.
  6. Tan E, Wilson TJ, Nahas MK, Clegg RM, Lilley DMJ, Ha T.
    A four-way junction accelerates hairpin ribozyme folding via a discrete intermediate.
    Proc Natl Acad Sci USA. 2003; 100(16): 9308-13. PMCID: PMC170914
  7. Toronov VY, Walker SA, Gupta R, Choi JH, Gratton E, Hueber DM, Webb A.
    The roles of changes in deoxyhemoglobin concentration and regional cerebral blood volume in the fMRI BOLD signal.
    NeuroImage. 2003; 19(4): 1521-31.
  8. Wolf M, Wolf U, Choi JH, Toronov VY, Paunescu LA, Michalos A, Gratton E.
    Fast cerebral functional signal in the 100-ms range detected in the visual cortex by frequency-domain near-infrared spectrophotometry.
    Psychophysiology. 2003; 40(4): 521-8.
  9. Gratton E, Breusegem SY, Sutin JDB, Ruan Q, Barry NP.
    Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods.
    J Biomed Opt. 2003; 8(3): 381-90.
  10. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RM, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM.
    Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function.
    J Invest Dermatol. 2003; 120(6): 998-1006.
  11. Wolf U, Wolf M, Choi JH, Levi M, Choudhury D, Hull S, Coussirat D, Paunescu LA, Safonova LP, Michalos A, Mantulin WW, Gratton E.
    Localized irregularities in hemoglobin flow and oxygenation in calf muscle in patients with peripheral vascular disease detected with near-infrared spectrophotometry.
    J Vasc Surg. 2003; 37(5): 1017-26.
  12. Czeslik C, Royer CA, Hazlett TL, Mantulin WW.
    Reorientational dynamics of enzymes adsorbed on quartz: a temperature-dependent time-resolved TIRF anisotropy study.
    Biophys J. 2003; 84(4): 2533-41. PMCID: PMC1302819
  13. Wurzburger RJ, Gupta R, Parnassa AP, Jain S, Wexler JA, Chu JL, Elkon KB, Blank RD.
    Use of GC clamps in DHPLC mutation scanning.
    Clin Med Res. 2003; 1(2): 111-118. PMCID: PMC1069033
  14. Zamai M, vandeVen MJ, Farao M, Gratton E, Ghiglieri A, Castelli MG, Fontana E, D'Argy R, Fiorino A, Pesenti E, Suarato A, Caiolfa VR.
    Camptothecin poly[n-(2-hydroxypropyl) methacrylamide] copolymers in antitopoisomerase-I tumor therapy: intratumor release and antitumor efficacy.
    Mol Cancer Ther. 2003; 2(1): 29-40.
  15. Safonova LP, Michalos A, Wolf U, Choi JH, Wolf M, Mantulin WW, Hueber DM, Gratton E.
    Diminished cerebral circulatory autoregulation in obstructive sleep apnea investigated by near-infrared spectroscopy.
    Sleep Research Online. 2003; 5(4): 123-132.

2002

  1. Behne MJ, Meyer JW, Hanson KM, Barry NP, Murata S, Crumrine D, Clegg RM, Gratton E, Holleran WM, Elias PM, Mauro TM.
    NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging.
    J Biol Chem. 2002; 277(49): 47399-406.
  2. Wolf M, Wolf U, Choi JH, Gupta R, Safonova LP, Paunescu LA, Michalos A, Gratton E.
    Functional frequency-domain near-infrared spectroscopy detects fast neuronal signal in the motor cortex.
    NeuroImage. 2002; 17(4): 1868-75.
  3. Ruan Q, Chen Y, Gratton E, Glaser M, Mantulin WW.
    Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy.
    Biophys J. 2002; 83(6): 3177-87. PMCID: PMC1302395
  4. Best KB, Ohran AJ, Hawes AC, Hazlett TL, Gratton E, Judd AM, Bell JD.
    Relationship between erythrocyte membrane phase properties and susceptibility to secretory phospholipase A2.
    Biochemistry. 2002; 41(47): 13982-8.
  5. Hanson KM, Behne MJ, Barry NP, Mauro TM, Gratton E, Clegg RM.
    Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient.
    Biophys J. 2002; 83(3): 1682-90. PMCID: PMC1302264
  6. Wolf M, Wolf U, Toronov VY, Michalos A, Paunescu LA, Choi JH, Gratton E.
    Different time evolution of oxyhemoglobin and deoxyhemoglobin concentration changes in the visual and motor cortices during functional stimulation: a near-infrared spectroscopy study.
    NeuroImage. 2002; 16(3 Pt 1): 704-12.
  7. Fahsel S, Pospiech EM, Zein M, Hazlett TL, Gratton E, Winter R.
    Modulation of concentration fluctuations in phase-separated lipid membranes by polypeptide insertion.
    Biophys J. 2002; 83(1): 334-44. PMCID: PMC1302151
  8. Hanson KM Clegg RM.
    Observation and quantification of ultraviolet-induced reactive oxygen species in ex vivo human skin.
    Photochem Photobiol. 2002; 76(1): 57-63.
  9. Bettati S, Campanini B, Vaccari S, Mozzarelli A, Schianchi G, Hazlett TL, Gratton E, Benci S.
    Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence.
    Biochim Biophys Acta. 2002; 1596(1): 47-54.
  10. Sánchez SA, Bagatolli LA, Gratton E, Hazlett TL.
    A two-photon view of an enzyme at work: Crotalus atrox venom PLA2 interaction with single-lipid and mixed-lipid giant unilamellar vesicles.
    Biophys J. 2002; 82(4): 2232-43. PMCID: PMC1302016
  11. Huang H, Dong CY, Kwon HS, Sutin JDB, Kamm RD, So PTC.
    Three-dimensional cellular deformation analysis with a two-photon magnetic manipulator workstation.
    Biophys J. 2002; 82(4): 2211-23. PMCID: PMC1302014
  12. Patel RC, Kumar U, Lamb DC, Eid JS, Rocheville M, Grant M, Rani A, Hazlett TL, Patel SC, Gratton E, Patel YC.
    Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells.
    Proc Natl Acad Sci USA. 2002; 99(5): 3294-9. PMCID: PMC122512
  13. Tricerri MA, Sánchez SA, Arnulphi C, Durbin DM, Gratton E, Jonas A.
    Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles.
    J Lipid Res. 2002; 43(2): 187-97.
  14. Breusegem SY, Clegg RM, Loontiens FG.
    Base-sequence specificity of Hoechst 33258 and DAPI binding to five (A/T)4 DNA sites with kinetic evidence for more than one high-affinity Hoechst 33258-AATT complex.
    J Mol Biol. 2002; 315(5): 1049-61.
  15. Sukhishvili SA, Chen Y, Müller JD, Gratton E, Schweizer KS, Granick S.
    Surface diffusion of Poly(ethylene glycol).
    Macromolecules. 2002; 35(5): 1776-1784.
  16. Chen Y, Müller JD, Ruan Q, Gratton E.
    Molecular brightness characterization of EGFP in vivo by fluorescence fluctuation spectroscopy.
    Biophys J. 2002; 82(1): 133-44. PMCID: PMC1302455
  17. Clegg RM.
    FRET tells us about proximities, distances, orientations and dynamic properties.
    J Biotechnol. 2002; 82(3): 177-9.

2001

  1. Jasuja R, Hazlett TL, Helms MK, Lee SH, Jameson DM, Larsen RW.
    Temperature dependence of photoinduced electron transfer within self-associated porphyrin: guanine monophosphate complexes.
    Chem Phys Lett. 2001; 350(5-6): 515-521.
  2. Ruan Q, Ruan K, Balny C, Glaser M, Mantulin WW.
    Protein folding pathways of adenylate kinase from E. coli: hydrostatic pressure and stopped-flow studies.
    Biochemistry. 2001; 40(48): 14706-14.
  3. Bismuto E, Gratton E, Lamb DC.
    Dynamics of ANS binding to tuna apomyoglobin measured with fluorescence correlation spectroscopy.
    Biophys J. 2001; 81(6): 3510-21. PMCID: PMC1301806
  4. Toronov VY, Webb A, Choi JH, Wolf M, Safonova LP, Wolf U, Gratton E.
    Study of local cerebral hemodynamics by frequency-domain near-infrared spectroscopy and correlation with simultaneously acquired functional magnetic resonance imaging.
    Opt Express. 2001; 9(8): 417-427.
  5. Gratton E, Barry NP, Beretta S, Celli A.
    Multiphoton fluorescence microscopy.
    Methods. 2001; 25(1): 103-10.
  6. Bagatolli LA Gratton E.
    Direct observation of lipid domains in free-standing bilayers using two-photon excitation fluorescence microscopy.
    J Fluoresc. 2001; 11(3): 141-160.
  7. Smith SK, Farnbach AR, Harris FM, Hawes AC, Jackson LR, Judd AM, Vest RS, Sánchez SA, Bell JD.
    Mechanisms by which intracellular calcium induces susceptibility to secretory phospholipase A2 in human erythrocytes.
    J Biol Chem. 2001; 276(25): 22732-22741.
  8. Sánchez SA, Chen Y, Müller JD, Gratton E, Hazlett TL.
    Solution and interface aggregation states of Crotalus atrox venom phospholipase A2 by two-photon excitation fluorescence correlation spectroscopy.
    Biochemistry. 2001; 40(23): 6903-11.
  9. Breusegem SY, Sadat-Ebrahimi SE, Douglas KT, Clegg RM, Loontiens FG.
    Increased stability and lifetime of the complex formed between DNA and meta-phenyl-substituted Hoechst dyes as studied by fluorescence titrations and stopped-flow kinetics.
    J Mol Biol. 2001; 308(4): 649-63.
  10. Tricerri MA, Agree AKB, Sánchez SA, Bronski J, Jonas A.
    Arrangement of apolipoprotein A-I in reconstituted high-density lipoprotein disks: an alternative model based on fluorescence resonance energy transfer experiments.
    Biochemistry. 2001; 40(16): 5065-74.
  11. Krasnowska EK, Bagatolli LA, Gratton E, Parasassi T.
    Surface properties of cholesterol-containing membranes detected by Prodan fluorescence.
    Biochim Biophys Acta. 2001; 1511(2): 330-40.
  12. Toronov VY, Webb A, Choi JH, Wolf M, Michalos A, Gratton E, Hueber DM.
    Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging.
    Med Phys. 2001; 28(4): 521-7.
  13. Chirico G, Bettati S, Mozzarelli A, Chen Y, Müller JD, Gratton E.
    Molecular heterogeneity of O-acetylserine sulfhydrylase by two-photon excited fluorescence fluctuation spectroscopy.
    Biophys J. 2001; 80(4): 1973-85. PMCID: PMC1301386
  14. Ferreira ST Gratton E.
    Hydration and protein substates: fluorescence of proteins in reverse micelles.
    J Mol Liq. 2001; 45(3): 253-272.
  15. van Rompaey E, Chen Y, Müller JD, Gratton E, van Craenenbroeck E, Engelborghs Y, de Smedt S, Demeester J.
    Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers.
    Biol Chem. 2001; 382(3): 379-386.
  16. Dietrich C, Bagatolli LA, Volovyk ZN, Thompson NL, Levi M, Jacobson KA, Gratton E.
    Lipid rafts reconstituted in model membranes.
    Biophys J. 2001; 80(3): 1417-28. PMCID: PMC1301333
  17. Dong CY, Buehler C, So PTC, French TE, Gratton E.
    Implementation of intensity-modulated laser diodes in time-resolved, pump-probe fluorescence microscopy.
    Appl Opt. 2001; 40(7): 1109-1115.
  18. Margeat E, Poujol N, Boulahtouf A, Chen Y, Müller JD, Gratton E, Cavailles V, Royer CA.
    The human estrogen receptor alpha dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure.
    J Mol Biol. 2001; 306(3): 433-42.
  19. Nayfeh MH, Barry NP, Therrien J, Akcakir O, Gratton E, Belomoin G.
    Stimulated blue emission in reconstituted films of ultrasmall silicon nanoparticles.
    Appl Phys Lett. 2001; 78(8): 1131-1133.
  20. Barcellona ML, Chen Y, Müller JD, Gratton E.
    4',6-diamidino-2-phenylindole (DAPI) interacts with rare structures of GC polymers.
    Eur Biophys J. 2001; 30(2): 98-109.

2000

  1. Bettati S, Benci S, Campanini B, Raboni S, Chirico G, Beretta S, Schnackerz KD, Hazlett TL, Gratton E, Mozzarelli A.
    Role of pyridoxal 5'-phosphate in the structural stabilization of O-acetylserine sulfhydrylase.
    J Biol Chem. 2000; 275(51): 40244-51.
  2. Nayfeh MH, Akcakir O, Belomoin G, Barry NP, Therrien J, Gratton E.
    Second harmonic generation in microcrystallite films of ultrasmall Si nanoparticles.
    Appl Phys Lett. 2000; 77(25): 4086-4088.
  3. Holub O, Seufferheld MJ, Gohlke C, Govindjee, Clegg RM.
    Fluorescence lifetime imaging (FLI) in real-time - a new technique in photosynthesis research.
    Photosynthetica. 2000; 8(4): 581-599.
  4. Tricerri MA, Agree AKB, Sánchez SA, Jonas A.
    Characterization of apolipoprotein A-I structure using a cysteine-specific fluorescence probe.
    Biochemistry. 2000; 39(47): 14682-91.
  5. Lamb DC, Schenk A, Röcker C, Nienhaus GU.
    Determining chemical rate coefficients using time-gated fluorescence correlation spectroscopy.
    J Phys Org Chem. 2000; 13(10): 654 - 658.
  6. Chen Y, Müller JD, Tetin SY, Tyner JD, Gratton E.
    Probing ligand protein binding equilibria with fluorescence fluctuation spectroscopy.
    Biophys J. 2000; 79(2): 1074-1084. PMCID: PMC1301003
  7. Lamb DC, Schenk A, Röcker C, Scalfi-Happ C, Nienhaus GU.
    Sensitivity enhancement in fluorescence correlation spectroscopy of multiple species using time-gated detection.
    Biophys J. 2000; 79(2): 1129-1138. PMCID: PMC1301008
  8. Sukhishvili SA, Chen Y, Müller JD, Gratton E, Schweizer KS, Granick S.
    Materials science: diffusion of a polymer 'pancake'.
    Nature. 2000; 406(6792): 146.
  9. Casavola C, Paunescu LA, Fantini S, Gratton E.
    Blood flow and oxygen consumption with near-infrared spectroscopy and venous occlusion: spatial maps and the effect of time and pressure of inflation.
    J Biomed Opt. 2000; 5(3): 269-76.
  10. Buehler C, Dong CY, So PTC, French TE, Gratton E.
    Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy.
    Biophys J. 2000; 79(1): 536-49. PMCID: PMC1300957
  11. Bagatolli LA Gratton E.
    A correlation between lipid domain shape and binary phospholipid mixture composition in free standing bilayers: a two-photon fluorescence microscopy study.
    Biophys J. 2000; 79(1): 434-47. PMCID: PMC1300947
  12. Bagatolli LA, Gratton E, Khan TK, Chong PLG.
    Two-photon fluorescence microscopy studies of bipolar tetraether giant liposomes from thermoacidophilic archaebacteria Sulfolobus acidocaldarius.
    Biophys J. 2000; 79(1): 416-25. PMCID: PMC1300945
  13. Zolese G, Falcioni G, Bertoli E, Galeazzi R, Wozniak M, Wypych Z, Gratton E, Ambrosini A.
    Steady-state and time resolved fluorescence of albumins interacting with N-oleylethanolamine, a component of the endogenous N-acylethanolamines.
    Proteins. 2000; 40(1): 39-48.
  14. Parasassi T, Yu W, Durbin DM, Kuriashkina LR, Gratton E, Maeda N, Ursini F.
    Two-photon microscopy of aorta fibers shows proteolysis induced by LDL hydroperoxides.
    Free Radic Biol Med. 2000; 28(11): 1589-1597.
  15. Frolov A, Petrescu A, Atshaves BP, So PTC, Gratton E, Serrero G, Schroeder F.
    High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
    J Biol Chem. 2000; 275(17): 12769-12780.
  16. Akcakir O, Therrien J, Belomoin G, Barry NP, Müller JD, Gratton E, Nayfeh MH.
    Detection of luminescent single ultra small silicon nanoparticles using fluctuation correlation spectroscopy.
    Appl Phys Lett. 2000; 76(14): 1857-1859.
  17. Bagatolli LA, Parasassi T, Gratton E.
    Giant phospholipid vesicles: comparison among the whole lipid sample characteristics using different preparation methods: a two photon fluorescence microscopy study.
    Chem Phys Lipids. 2000; 105(2): 135-47.
  18. Toronov VY, Franceschini MA, Filiaci ME, Fantini S, Wolf M, Michalos A, Gratton E.
    Near-infrared study of fluctuations in cerebral hemodynamics during rest and motor stimulation: temporal analysis and spatial mapping.
    Med Phys. 2000; 27(4): 801-15.
  19. Stankovic MR, Maulik D, Rosenfeld W, Stubblefield PG, Kofinas AD, Gratton E, Franceschini MA, Fantini S, Hueber DM.
    Role of frequency domain optical spectroscopy in the detection of neonatal brain hemorrhage - a newborn piglet study.
    J Mat Fet Med. 2000; 9(2): 142-9.
  20. Tetin SY Hazlett TL.
    Optical spectroscopy in studies of antibody-hapten interactions.
    Methods. 2000; 20(3): 341-61.
  21. Eid JS, Müller JD, Gratton E.
    Data acquisition card for fluctuation correlation spectroscopy allowing full access to the detected photon sequence.
    Rev Sci Instrum. 2000; 71(2): 361-368.
  22. Franceschini MA, Toronov VY, Filiaci ME, Gratton E, Fantini S.
    On-line optical imaging of the human brain with 160-ms temporal resolution.
    Opt Express. 2000; 6(3): 49-57.
  23. Arcangeli C, Yu W, Cannistraro S, Gratton E.
    Two-photon autofluorescence microscopy and spectroscopy of Antarctic fungus: new approach for studying effects of UV-B irradiation.
    Biopolymers. 2000; 57(4): 218-25.
  24. Müller JD, Chen Y, Gratton E.
    Resolving heterogeneity on the single molecular level with the photon-counting histogram.
    Biophys J. 2000; 78(1): 474-86. PMCID: PMC1300655
  25. Bagatolli LA Gratton E.
    Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures.
    Biophys J. 2000; 78(1): 290-305. PMCID: PMC1300637
  26. Fantini S Gratton E.
    Fluorescence photon-density waves in optically diffusive media.
    Optics Communications. 2000; 173(1): 73-79.

1999

  1. Nayfeh MH, Akcakir O, Therrien J, Yamani Z, Barry NP, Yu W, Gratton E.
    Highly nonlinear photoluminescence threshold in porous silicon.
    Appl Phys Lett. 1999; 75(26): 4112.
  2. Davidson WS, Arnvig-McGuire K, Kennedy A, Kosman J, Hazlett TL, Jonas A.
    Structural organization of the N-terminal domain of apolipoprotein A-I: studies of tryptophan mutants.
    Biochemistry. 1999; 38(43): 14387-95.
  3. Bagatolli LA, Parasassi T, Fidelio GD, Gratton E.
    A model for the interaction of 6-lauroyl-2-(N,N-dimethylamino)naphthalene with lipid environments: implications for spectral properties.
    Photochem Photobiol. 1999; 70(4): 557-64.
  4. Chen Y, Müller JD, Berland KM, Gratton E.
    Fluorescence fluctuation spectroscopy.
    Methods. 1999; 19(2): 234-52.
  5. Bagatolli LA Gratton E.
    Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles.
    Biophys J. 1999; 77(4): 2090-101. PMCID: PMC1300490
  6. Parasassi T, Gratton E, Zajicek HK, Levi M, Yu W.
    Detecting membrane lipid microdomains by two-photon fluorescence microscopy.
    IEEE Eng Med Biol Mag. 1999; 18(5): 92-9.
  7. Stankovic MR, Maulik D, Rosenfeld W, Stubblefield PG, Kofinas AD, Drexler S, Nair R, Franceschini MA, Hueber DM, Gratton E, Fantini S.
    Real-time optical imaging of experimental brain ischemia and hemorrhage in neonatal piglets.
    J Perinat Med. 1999; 27(4): 279-86.
  8. Chen Y, Müller JD, So PTC, Gratton E.
    The photon counting histogram in fluorescence fluctuation spectroscopy.
    Biophys J. 1999; 77(1): 553-67. PMCID: PMC1300352
  9. Franceschini MA, Gratton E, Fantini S.
    Noninvasive optical method of measuring tissue and arterial saturation:an application to absolute pulse oximetry of the brain.
    Opt Lett. 1999; 24(12): 829-831.
  10. Fantini S, Hueber DM, Franceschini MA, Gratton E, Rosenfeld W, Stubblefield PG, Maulik D, Stankovic MR.
    Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy.
    Phys Med Biol. 1999; 44(6): 1543-63.
  11. Fantini S, Franceschini MA, Gratton E, Hueber DM, Rosenfeld W, Maulik D, Stubblefield PG, Stankovic MR.
    Non-invasive optical mapping of the piglet brain in real time.
    Opt Express. 1999; 4(8): 308-314.
  12. Casavola C, Paunescu LA, Fantini S, Franceschini MA, Lugarà PM, Gratton E.
    Application of near-infrared tissue oxymetry to the diagnosis of peripheral vascular disease.
    Clin Hemorheol Microcirc. 1999; 21(3-4): 389-393.
  13. Lasagna M, Gratton E, Jameson DM, Brunet JE.
    Apohorseradish peroxidase unfolding and refolding: intrinsic tryptophan fluorescence studies.
    Biophys J. 1999; 76(1): 443-450. PMCID: PMC1302533

1998

  1. Parasassi T, Krasnowska EK, Bagatolli LA, Gratton E.
    Laurdan and Prodan as polarity-sensitive fluorescent membrane probes.
    J Fluoresc. 1998; 8(4): 365-373.
  2. Franceschini MA, Fantini S, Paunescu LA, Maier JS, Gratton E.
    Influence of a superficial layer in the quantitative spectroscopic study of strongly scattering media.
    Appl Opt. 1998; 37(31): 7447-7458.
  3. di Venere A, Mei G, Gilardi G, Rosato N, de Matteis F, McKay R, Gratton E, Finazzi-Agrò A.
    Resolution of the heterogeneous fluorescence in multi-tryptophan proteins: ascorbate oxidase.
    Eur J Biochem. 1998; 257(2): 337-43.
  4. Helms MK, Hazlett TL, Mizuguchi H, Hasemann CA, Uyeda K, Jameson DM.
    Site-directed mutants of rat testis fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase: localization of conformational alterations induced by ligand binding.
    Biochemistry. 1998; 37(40): 14057-64.
  5. Sánchez SA, Hazlett TL, Brunet JE, Jameson DM.
    Aggregation states of mitochondrial malate dehydrogenase.
    Protein Sci. 1998; 7(10): 2184-9. PMCID: PMC2143840
  6. Chance B, Cope M, Gratton E, Ramanujam N, Tromberg BJ.
    Phase measurement of light absorption and scatter in human tissue.
    Rev Sci Instrum. 1998; 69(10): 3457-3481.
  7. Gilmore AM, Shinkarev VP, Hazlett TL, Govindjee.
    Quantitative analysis of the effects of intrathylakoid pH and xanthophyll cycle pigments on Chlorophyll A fluorescence lifetime distributions and intensity in thylakoids.
    Biochemistry. 1998; 37(39): 13582-93.
  8. Toronov VY, Filiaci ME, Fantini S, Gratton E.
    Photon-density wave correlation spectroscopy detects large-scale fluctuations in turbid media.
    Phys Rev E. 1998; 58(2): 2288-2297.
  9. Brune M, Hunter JL, Howell SA, Martin SR, Hazlett TL, Corrie JE, Webb MR.
    Mechanism of inorganic phosphate interaction with phosphate binding protein from Escherichia coli.
    Biochemistry. 1998; 37(29): 10370-80.
  10. So PTC, König K, Berland KM, Dong CY, French TE, Buehler C, Ragan TM, Gratton E.
    New time-resolved techniques in two-photon microscopy.
    Cell Mol Biol (Noisy-le-grand). 1998; 44(5): 771-793.
  11. Bagatolli LA, Gratton E, Fidelio GD.
    Water dynamics in glycosphingolipid aggregates studied by LAURDAN fluorescence.
    Biophys J. 1998; 75(1): 331-41. PMCID: PMC1299702
  12. Krasnowska EK, Gratton E, Parasassi T.
    Prodan as a membrane surface fluorescence probe: partitioning between water and phospholipid phases.
    Biophys J. 1998; 74(4): 1984-93. PMCID: PMC1299539
  13. Walker SA, Boas DA, Gratton E.
    Photon density waves scattered from cylindrical inhomogeneities: theory and experiments.
    Appl Opt. 1998; 37(10): 1935-1944.
  14. Fantini S, Walker SA, Franceschini MA, Kaschke M, Schlag PM, Moesta KT.
    Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods.
    Appl Opt. 1998; 37(10): 1982-1989.
  15. Masters BR, So PTC, Gratton E.
    Optical biopsy of In vivo human skin: multi-photon excitation microscopy.
    Lasers Med Sci. 1998; 13(3): 197-204.

1997

  1. Gratton G, Fabiani M, Corballis PM, Hood DC, Goodman-Wood MR, Hirsch J, Kim K, Friedman D, Gratton E.
    Fast and localized event-related optical signals (EROS) in the human occipital cortex: comparisons with the visual evoked potential and fMRI.
    NeuroImage. 1997; 6(3): 168-80.
  2. Gratton E, Fantini S, Franceschini MA, Gratton G, Fabiani M.
    Measurements of scattering and absorption changes in muscle and brain.
    Philos Trans R Soc Lond, B, Biol Sci. 1997; 352(1354): 727-35. PMCID: PMC1691951
  3. Franceschini MA, Moesta KT, Fantini S, Gaida G, Gratton E, Jess H, Mantulin WW, Seeber M, Schlag PM, Kaschke M.
    Frequency-domain techniques enhance optical mammography: initial clinical results.
    Proc Natl Acad Sci USA. 1997; 94(12): 6468-6473. PMCID: PMC21073
  4. Parasassi T, Gratton E, Yu W, Wilson PV, Levi M.
    Two-photon fluorescence microscopy of laurdan generalized polarization domains in model and natural membranes.
    Biophys J. 1997; 72(6): 2413-29. PMCID: PMC1184441
  5. Masters BR, So PTC, Gratton E.
    Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin.
    Biophys J. 1997; 72(6): 2405-12. PMCID: PMC1184440
  6. Franceschini MA, Fantini S, Cerussi AE, Barbieri BB, Chance B, Gratton E.
    Quantitative spectroscopic determination of hemoglobin concentration and saturation in a turbid medium: analysis of the effect of water absorption.
    J Biomed Opt. 1997; 2(2): 174-153.
  7. Bernsdorff C, Wolf A, Winter R, Gratton E.
    Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid-cholesterol bilayers.
    Biophys J. 1997; 72(3): 1264-77. PMCID: PMC1184509
  8. French TE, So PTC, Weaver DJ Jr, Coelho-Sampaio T, Gratton E, Voss EW Jr, Carrero J.
    Two-photon fluorescence lifetime imaging microscopy of macrophage-mediated antigen processing.
    J Microsc. 1997; 185(Pt 3): 339-53.
  9. König K, So PTC, Mantulin WW, Gratton E.
    Cellular response to near-infrared femotosecond laser pulses in two-photon microscopes.
    Opt Lett. 1997; 22(2): 135-136.
  10. Barshtein G, Bergelson L, Dagan A, Gratton E, Yedgar S.
    Membrane lipid order of human red blood cells is altered by physiological levels of hydrostatic pressure.
    Am J Physiol Heart Circ Physiol. 1997; 272(1 Pt 2): H538-43.
  11. Cerussi AE, Maier JS, Fantini S, Franceschini MA, Mantulin WW, Gratton E.
    Experimental verification of a theory for the time-resolved fluorescence spectroscopy of thick tissues.
    Appl Opt. 1997; 36(1): 116-124.
  12. Fantini S, Franceschini MA, Gratton E.
    Effective source term in the diffusion equation for photon transport in turbid media.
    Appl Opt. 1997; 36(1): 156-163.
  13. Walker SA, Fantini S, Gratton E.
    Image reconstruction by backprojection from frequency-domain optical measurements in highly scattering media.
    Appl Opt. 1997; 36(1): 170-174.
  14. Dong CY, So PTC, Buehler C, Gratton E.
    Spatial resolution in scanning pump-probe fluorescence microscopy.
    Optik. 1997; 106(1): 7-14.

1996

  1. Zolese G, Giambanco I, Curatola G, Staffolani R, Gratton E, Donato R.
    Time-resolved fluorescence of S-100a protein: effect of Ca2+, Mg2+ and unilamellar vesicles of egg phosphatidylcholine.
    Cell Calcium. 1996; 20(6): 465-474.
  2. Davidson WS, Hazlett TL, Mantulin WW, Jonas A.
    The role of apolipoprotein AI domains in lipid binding.
    Proc Natl Acad Sci USA. 1996; 93(24): 13605-10. PMCID: PMC19365
  3. König K, So PTC, Mantulin WW, Tromberg BJ, Gratton E.
    Two-photon excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress.
    J Microsc. 1996; 183(Pt 3): 197-204.
  4. Gilmore AM, Hazlett TL, Debrunner PG, Govindjee.
    Comparative time-resolved photosystem II Chlorophyll A fluorescence analyses reveal distinctive differences between photoinhibitory reaction center damage and xanthophyll cycle-dependent energy dissipation.
    Photochem Photobiol. 1996; 64(3): 552-63.
  5. Berland KM, So PTC, Chen Y, Mantulin WW, Gratton E.
    Scanning two-photon fluctuation correlation spectroscopy: particle counting measurements for detection of molecular aggregation.
    Biophys J. 1996; 71(1): 410-20. PMCID: PMC1233492
  6. Bilderback T, Fulmer TJ, Mantulin WW, Glaser M.
    Substrate binding causes movement in the ATP binding domain of Escherichia coli adenylate kinase.
    Biochemistry. 1996; 35(19): 6100-6.
  7. Barcellona ML Gratton E.
    Fluorescence anisotropy of DNA/DAPI complex: torsional dynamics and geometry of the complex.
    Biophys J. 1996; 70(5): 2341-51. PMCID: PMC1225209
  8. Fishkin JB, Fantini S, vandeVen MJ, Gratton E.
    Gigahertz photon density waves in a turbid medium: theory and experiments.
    Phys Rev E. 1996; 53(3): 2307-2319.
  9. Parasassi T Gratton E.
    Comments on 1,6-diphenyl-1,3,5-hexatriene fluorescence decrease at critical cholesterol concentration in phospholipid membranes.
    Biophys J. 1996; 70(3): 1560-2. PMCID: PMC1225084
  10. Yu W, So PTC, French TE, Gratton E.
    Fluorescence generalized polarization of cell membranes: a two-photon scanning microscopy approach.
    Biophys J. 1996; 70(2): 626-36. PMCID: PMC1224964
  11. Bismuto E, Sirangelo I, Irace G, Gratton E.
    Pressure-induced perturbation of apomyoglobin structure: fluorescence studies on native and acidic compact forms.
    Biochemistry. 1996; 35(4): 1173-8.
  12. Barcellona ML Gratton E.
    Torsional dynamics and orientation of DNA-DAPI complexes.
    Biochemistry. 1996; 35(1): 321-33.
  13. Barshtein G, Bergelson L, Gratton E, Yedgar S.
    Human red blood cell shape and volume are changed by physiological levels of hydrostatic pressure.
    J Basic Clin Physiol Pharmacol. 1996; 7(4): 321-9.
  14. Bismuto E, Irace G, Sirangelo I, Gratton E.
    Pressure-induced perturbation of ANS-apomyoglobin complex: frequency domain fluorescence studies on native and acidic compact states.
    Protein Sci. 1996; 5(1): 121-6. PMCID: PMC2143254
  15. Fantini S, Franceschini MA, Gaida G, Gratton E, Jess H, Mantulin WW, Moesta KT, Schlag PM, Kaschke M.
    Frequency-domain optical mammography: edge effect corrections.
    Med Phys. 1996; 23(1): 149-57.

1995

  1. Dong CY, So PTC, French TE, Gratton E.
    Fluorescence lifetime imaging by asynchronous pump-probe microscopy.
    Biophys J. 1995; 69(6): 2234-42. PMCID: PMC1236462
  2. Parasassi T, Giusti AM, Raimondi M, Ravagnan G, Sapora O, Gratton E.
    Cholesterol protects the phospholipid bilayer from oxidative damage.
    Free Radic Biol Med. 1995; 19(4): 511-6.
  3. Berberan-Santos MN, Canceill J, Gratton E, Jullien L, Lehn JM, So PTC, Sutin JDB, Valeur B.
    Multichromophoric cyclodextrins. 3. Investigation of dynamics of energy hopping by frequency-domain fluorometry.
    J Phys Chem. 1995; 100(1): 15-20.
  4. Gratton G, Fabiani M, Friedman D, Franceschini MA, Fantini S, Corballis PM, Gratton E.
    Rapid changes of optical parameters in the human brain during a tapping task.
    J Cogn Neurosci. 1995; 7(4): 446-456.
  5. Bernsdorff C, Winter R, Hazlett TL, Gratton E.
    Influence of Cholesterol and b-Sitosterol on the dynamic behaviour of DPPC as detected by TMA-DPH and PyrPc fluorescence: a fluorescence lifetime distribution and time-resolved anisotropy study.
    Ber Bunsen Phys Chem. 1995; 99(12): 1479-1488.
  6. Watson BS, Hazlett TL, Eccleston JF, Davis C, Jameson DM, Johnson AE.
    Macromolecular arrangement in the aminoacyl-tRNA.elongation factor Tu.GTP ternary complex. A fluorescence energy transfer study.
    Biochemistry. 1995; 34(24): 7904-12.
  7. So PTC, French TE, Yu W, Berland KM, Dong CY, Gratton E.
    Time-resolved fluorescence microscopy using two-photon excitation.
    Bioimaging. 1995; 3(2): 49-63.
  8. Giusti AM, Gratton E, Parasassi T, Raimondi M, Ravagnan G.
    Cholesterol effects on membrane structure and dynamics as detected by Laurdan fluorescence.
    Biochimica in Italia. 1995; 3: 64-72.
  9. Parasassi T, Giusti AM, Raimondi M, Gratton E.
    Abrupt modifications of phospholipid bilayer properties at critical cholesterol concentrations.
    Biophys J. 1995; 68(5): 1895-902. PMCID: PMC1282093
  10. Carrero J, Jameson DM, Gratton E.
    Oxygen penetration and diffusion into myoglobin revealed by quenching of zincprotoporphyrin IX fluorescence.
    Biophys Chem. 1995; 54(2): 143-54.
  11. Gilmore AM, Hazlett TL, Govindjee.
    Xanthophyll cycle-dependent quenching of photosystem II Chlorophyll A fluorescence: formation of a quenching complex with a short fluorescence lifetime.
    Proc Natl Acad Sci USA. 1995; 92(6): 2273-7. PMCID: PMC42466
  12. de Blasi RA, Fantini S, Franceschini MA, Ferrari M, Gratton E.
    Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer.
    Med Biol Eng Comput. 1995; 33(2): 228-30.
  13. Gratton E Parasassi T.
    Fluorescence lifetime distributions in membrane systems.
    J Fluoresc. 1995; 5(1): 51-57.
  14. Parasassi T Gratton E.
    Membrane lipid domains and dynamics as detected by Laurdan fluorescence.
    J Fluoresc. 1995; 5(1): 59-69.
  15. Fishkin JB, So PTC, Cerussi AE, Gratton E, Fantini S, Franceschini MA.
    Frequency-domain method for measuring spectral properties in multiple-scattering media: methemoglobin absorption spectrum in a tissuelike phantom.
    Appl Opt. 1995; 34(7): 1143-1155.
  16. Berland KM, So PTC, Gratton E.
    Two-photon fluorescence correlation spectroscopy: method and application to the intracellular environment.
    Biophys J. 1995; 68(2): 694-701. PMCID: PMC1281733
  17. Fantini S, Franceschini MA, Maier JS, Walker SA, Barbieri BB, Gratton E.
    Frequency-domain multichannel optical detector for noninvasive tissue spectroscopy and oximetry.
    Opt Eng. 1995; 34(1): 32-42.
  18. Gratton E Fishkin JB.
    Optical spectroscopy of tissue-like phantoms using photon density waves.
    Comm Mol Cell Biophys. 1995; 8(6): 307-357.

1994

  1. Maier JS, Walker SA, Fantini S, Franceschini MA, Gratton E.
    Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared.
    Opt Lett. 1994; 19(24): 2062-2064.
  2. Maris MB, Gratton E, Maier JS, Mantulin WW, Chance B.
    Functional near-infrared imaging of deoxygenated hemoglobin during exercise of the finger extensor muscles using the frequency-domain technique.
    Bioimaging. 1994; 2(4): 174-183.
  3. Fantini S, Franceschini MA, Gratton E.
    Semi-infinite geometry boundary problem for light migration in highly scattering media: a frequency-domain study in the diffusion approximation.
    J Opt Soc Am B. 1994; 11(10): 2128.
  4. Fantini S, Franceschini MA, Fishkin JB, Barbieri BB, Gratton E.
    Quantitative determination of the absorption spectra of chromophores in strongly scattering media: light-emitting-diode-based technique.
    Appl Opt. 1994; 33(22): 5204-5213.
  5. Ferreira ST Gratton E.
    Anisotropic rotational diffusion of the Adenine moiety in 1,N6-Ethenoadenosine Triphosphate in viscous solvents investigated by time-resolved fluorescence spectroscopy.
    J Am Chem Soc. 1994; 116(13): 5791-5795.
  6. Ferreira ST, Stella L, Gratton E.
    Conformational dynamics of bovine Cu, Zn superoxide dismutase revealed by time-resolved fluorescence spectroscopy of the single tyrosine residue.
    Biophys J. 1994; 66(4): 1185-96. PMCID: PMC1275826
  7. Gratton G, Maier JS, Fabiani M, Mantulin WW, Gratton E.
    Feasibility of intracranial near-infrared optical scanning.
    Psychophysiology. 1994; 31(2): 211-5.
  8. Parasassi T, di Stefano M, Loiero M, Ravagnan G, Gratton E.
    Cholesterol modifies water concentration and dynamics in phospholipid bilayers: a fluorescence study using Laurdan probe.
    Biophys J. 1994; 66(3): 763-8. PMCID: PMC1275774
  9. Parasassi T, Giusti AM, Gratton E, Monaco E, Raimondi M, Ravagnan G, Sapora O.
    Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation.
    Int J Radiat Biol. 1994; 65(3): 329-34.
  10. Brunet JE, Vargas V, Gratton E, Jameson DM.
    Hydrodynamics of horseradish peroxidase revealed by global analysis of multiple fluorescence probes.
    Biophys J. 1994; 66(2): 446-53. PMCID: PMC1275712
  11. Parasassi T, di Stefano M, Loiero M, Ravagnan G, Gratton E.
    Influence of cholesterol on phospholipid bilayers phase domains as detected by Laurdan fluorescence.
    Biophys J. 1994; 66(1): 120-32. PMCID: PMC1275671
  12. Silva N Jr, Gratton E, Mei G.
    Protein fluorescence and conformational substates: the dynamics of human superoxide dismutase.
    Comm Mol Cell Biophys. 1994; 8(4): 217-242.

1993

  1. Hazlett TL, Moore KJ, Lowe PN, Jameson DM, Eccleston JF.
    Solution dynamics of p21ras proteins bound with fluorescent nucleotides: a time-resolved fluorescence study.
    Biochemistry. 1993; 32(49): 13575-83.
  2. Parasassi T, Loiero M, Raimondi M, Ravagnan G, Gratton E.
    Absence of lipid gel-phase domains in seven mammalian cell lines and in four primary cell types.
    Biochim Biophys Acta. 1993; 1153(2): 143-54.
  3. Silva N Jr, Gratton E, Mei G, Rosato N, Rusch RM, Finazzi-Agrò A.
    Molten globule monomers in human superoxide dismutase.
    Biophys Chem. 1993; 48(2): 171-82.
  4. Bismuto E, Gratton E, Sirangelo I, Irace G.
    Structure and dynamics of the acidic compact state of apomyoglobin by frequency-domain fluorometry.
    Eur J Biochem. 1993; 218(1): 213-9.
  5. Tetin SY, Rumbley CA, Hazlett TL, Voss EW Jr.
    Elucidation of anti-ssDNA autoantibody BV 04-01 binding interactions with homooligonucleotides.
    Biochemistry. 1993; 32(35): 9011-7.
  6. Govindjee, vandeVen MJ, Cao J, Royer CA, Gratton E.
    Multifrequency cross-correlation phase fluorometry of Chlorophyll A fluorescence in Thylakoid and PSII-enriched membranes.
    Photochem Photobiol. 1993; 58(3): 438-45.
  7. Zolese G, Staffolani R, Mazzanti L, Gratton E.
    Effect of divalent cations on Na+,K+-ATPase obtained from human placenta.
    FEBS Lett. 1993; 323(1-2): 11-4.
  8. van der Meer BW, Raymer MA, Wagoner SL, Hackney RL, Beechem JM, Gratton E.
    Designing matrix models for fluorescence energy transfer between moving donors and acceptors.
    Biophys J. 1993; 64(4): 1243-63. PMCID: PMC1262441
  9. Fiorini R, Curatola G, Kantar A, Giorgi PL, Gratton E.
    Use of Laurdan fluorescence in studying plasma membrane organization of polymorphonuclear leukocytes during the respiratory burst.
    Photochem Photobiol. 1993; 57(3): 438-441.
  10. Levi M, Wilson PV, Cooper OJ, Gratton E.
    Lipid phases in renal brush border membranes revealed by Laurdan fluorescence.
    Photochem Photobiol. 1993; 57(3): 420-5.
  11. Parasassi T, Ravagnan G, Rusch RM, Gratton E.
    Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence.
    Photochem Photobiol. 1993; 57(3): 403-10.
  12. Gratton E, Mantulin WW, vandeVen MJ, Fishkin JB, Maris MB, Chance B.
    A novel approach to laser tomography.
    Bioimaging. 1993; 1(1): 40-46.
  13. Jonas A, von Eckardstein A, Churgay L, Mantulin WW, Assmann G.
    Structural and functional properties of natural and chemical variants of apolipoprotein A-I.
    Biochim Biophys Acta. 1993; 1166(2-3): 202-10.
  14. Fishkin JB Gratton E.
    Propagation of photon-density waves in strongly scattering media containing an absorbing semi-infinite plane bounded by a straight edge.
    J Opt Soc Am A. 1993; 10(1): 127-40.

1992

  1. Tetin SY, Mantulin WW, Denzin LK, Weidner KM, Voss EW Jr.
    Comparative circular dichroism studies of an anti-fluorescein monoclonal antibody (Mab 4-4-20) and its derivatives.
    Biochemistry. 1992; 31(48): 12029-34.
  2. Parasassi T, di Stefano M, Ravagnan G, Sapora O, Gratton E.
    Membrane aging during cell growth ascertained by Laurdan generalized polarization.
    Exp Cell Res. 1992; 202(2): 432-9.
  3. Parasassi T Gratton E.
    Packing of phospholipid vesicles studied by oxygen quenching of Laurdan fluorescence.
    J Fluoresc. 1992; 2(3): 167-174.
  4. Mei G, Rosato N, Silva N Jr, Rusch RM, Gratton E, Savini I, Finazzi-Agrò A.
    Denaturation of human Cu/Zn superoxide dismutase by guanidine hydrochloride: a dynamic fluorescence study.
    Biochemistry. 1992; 31(32): 7224-30.
  5. Parasassi T, Ravagnan G, Sapora O, Gratton E.
    Membrane oxidative damage induced by ionizing radiation detected by diphenylhexatriene fluorescence lifetime distributions.
    Int J Radiat Biol. 1992; 61(6): 791-6.
  6. Gratton E, Silva N Jr, Mei G, Rosato N, Savini I, Finazzi-Agrò A.
    Fluorescence lifetime distribution of folded and unfolded proteins.
    Int J Quant Chem. 1992; 42(5): 1479-1489.

1991

  1. Reinhart GD, Marzola P, Jameson DM, Gratton E.
    A method for on-line background subtraction in frequency domain fluorometry.
    J Fluoresc. 1991; 1(3): 153-162.
  2. Marzola P Gratton E.
    Hydration and protein dynamics: frequency domain fluorescence spectroscopy of proteins in reverse micelles.
    J Phys Chem. 1991; 95(23): 9488-9495.
  3. Parasassi T, de Stasio G, Ravagnan G, Rusch RM, Gratton E.
    Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence.
    Biophys J. 1991; 60(1): 179-89. PMCID: PMC1260049
  4. Barcellona ML Gratton E.
    A molecular approach to 4',6-diamidine-2-phenylindole (DAPI) photophysical behaviour at different pH values.
    Biophys Chem. 1991; 40(3): 223-9.
  5. Wang S, Beechem JM, Gratton E, Glaser M.
    Orientational distribution of 1,6-diphenyl-1,3,5-hexatriene in phospholipid vesicles as determined by global analysis of frequency domain fluorimetry data.
    Biochemistry. 1991; 30(22): 5565-72.
  6. Arduini A, vandeVen MJ, Shohet SB, Mancinelli G, Gratton E.
    Measurement and analysis of triplet-state lifetimes by multifrequency cross-correlation phase and modulation phosphorimetry.
    Anal Biochem. 1991; 195(2): 327-329.
  7. Feddersen BA, Piston DW, Gratton E.
    Reply to "Comment on 'Digital parallel acquisition in frequency domain fluorometry' " [Rev. Sci. Instrum. 60, 2929 (1989)].
    Rev Sci Instrum. 1991; 62(6): 1674.
  8. di Iorio EE, Hiltpold UR, Filipovic D, Winterhalter KH, Gratton E, Vitrano E, Cupane A, Leone M, Cordone L.
    Protein dynamics. Comparative investigation on heme-proteins with different physiological roles.
    Biophys J. 1991; 59(3): 742-54. PMCID: PMC1281236
  9. Chance B, Leigh JS, Gratton E.
    New Image.
    Nature. 1991; 349(6311): 660.
  10. Axelsen PH, Gratton E, Prendergast FG.
    Experimentally verifying molecular dynamics simulations through fluorescence anisotropy measurements.
    Biochemistry. 1991; 30(5): 1173-9.
  11. Parasassi T, de Stasio G, Rusch RM, Gratton E.
    A photophysical model for diphenylhexatriene fluorescence decay in solvents and in phospholipid vesicles.
    Biophys J. 1991; 59(2): 466-75. PMCID: PMC1281163

1990

  1. Pin S, Royer CA, Gratton E, Alpert B, Weber G.
    Subunit interactions in hemoglobin probed by fluorescence and high-pressure techniques.
    Biochemistry. 1990; 29(39): 9194-202.
  2. Rosato N, Gratton E, Mei G, Finazzi-Agrò A.
    Fluorescence lifetime distributions in human superoxide dismutase. Effect of temperature and denaturation.
    Biophys J. 1990; 58(4): 817-22. PMCID: PMC1281028
  3. Royer CA, Gardner JA, Beechem JM, Brochon JC, Matthews KS.
    Resolution of the fluorescence decay of the two tryptophan residues of lac repressor using single tryptophan mutants.
    Biophys J. 1990; 58(2): 363-378. PMCID: PMC1280978
  4. Barcellona ML, Cardiel G, Gratton E.
    Time-resolved fluorescence of DAPI in solution and bound to polydeoxynucleotides.
    Biochem Biophys Res Comm. 1990; 170(1): 270-80.
  5. Zolese G, Gratton E, Curatola G.
    Phosphatidic acid affects structural organization of phosphatidylcholine liposomes. A study of 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1-(4-trimethylammonium-phenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH) fluorescence decay using distributional analysis.
    Chem Phys Lipids. 1990; 55(1): 29-39.
  6. VanderMeulen DL, Nealon DG, Gratton E, Jameson DM.
    Excitation wavelength dependent fluorescence anisotropy of eosin-myosin adducts. Evidence for anisotropic rotations.
    Biophys Chem. 1990; 36(2): 177-84.
  7. Parasassi T, de Stasio G, D'Ubaldo A, Gratton E.
    Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence.
    Biophys J. 1990; 57(6): 1179-1186. PMCID: PMC1280828
  8. Rosato N, Gratton E, Mei G, Savini I, Finazzi-Agrò A.
    Dynamic fluorescence in copper proteins. Selected examples.
    BioMetals. 1990; 3(2): 133-6.
  9. Barcellona ML, Cardiel G, Gratton E.
    DAPI fluorescence decay process: a global analytical approach proves a ground-state heterogeneity with interconversion.
    Ital J Biochem. 1990; 39(3): 179A-181A.
  10. Rosato N, Mei G, Gratton E, Bannister JV, Bannister WH, Finazzi-Agrò A.
    A time-resolved fluorescence study of human copper-zinc superoxide dismutase.
    Biophys Chem. 1990; 36(1): 41-6.
  11. Govindjee, vandeVen MJ, Preston C, Seibert M, Gratton E.
    Chlorophyll A fluorescence lifetime distributions in open and closed Photosystem II reaction center preparations.
    Biochim Biophys Acta. 1990; 1015(2): 173-9.
  12. Parasassi T, de Stasio G, Miccheli A, Bruno F, Conti F, Gratton E.
    Abscisic acid-induced microheterogeneity in phospholipid vesicle. A fluorescence study.
    Biophys Chem. 1990; 35(1): 65-73.
  13. Barcellona ML Gratton E.
    The fluorescence properties of a DNA probe. 4'-6-Diamidino-2-phenylindole (DAPI).
    Eur Biophys J. 1990; 17(6): 315-23.

1989

  1. Barcellona ML Gratton E.
    Fluorescence lifetime distributions of DNA-4',6-diamidino-2-phenylindole complex.
    Biochim Biophys Acta. 1989; 993(2-3): 174-8.
  2. Piston DW Gratton E.
    Orientational exchange approach to fluorescence anisotropy decay.
    Biophys J. 1989; 56(6): 1083-91. PMCID: PMC1280612
  3. Fiorini R, Gratton E, Curatola G.
    Effect of cholesterol on membrane microheterogeneity: a study using 1,6-diphenyl-1,3,5-hexatriene fluorescence lifetime distributions.
    Biochim Biophys Acta. 1989; 1006(2): 198-202.
  4. Wratten ML, Gratton E, vandeVen MJ, Sevanian A.
    DPH lifetime distributions in vesicles containing phospholipid hydroperoxides.
    Biochem Biophys Res Comm. 1989; 164(1): 169-75.
  5. Barbieri BB, de Piccoli F, Gratton E.
    Synthesizers' phase noise in frequency-domain fluorometry.
    Rev Sci Instrum. 1989; 60(10): 3201-3206.
  6. Feddersen BA, Piston DW, Gratton E.
    Digital parallel acquisition in frequency domain fluorimetry.
    Rev Sci Instrum. 1989; 60(9): 2929-2936.
  7. Royer CA, Rusch RM, Scarlata SF.
    Salt effects on histone subunit interactions as studied by fluorescence spectroscopy.
    Biochemistry. 1989; 28(16): 6631-6637.
  8. Scarlata SF, Ropp T, Royer CA.
    Histone subunit interactions as investigated by high pressure.
    Biochemistry. 1989; 28(16): 6637-6641.
  9. Piston DW, Marriott GM, Radivoyevich T, Clegg RM, Jovin TM, Gratton E.
    Wide-band acousto-optic light modulator for frequency domain fluorometry and phosphorimetry.
    Rev Sci Instrum. 1989; 60(8): 2596-2600.
  10. Beechem JM.
    A second generation global analysis program for the recovery of complex inhomogeneous fluorescence decay kinetics.
    Chem Phys Lipids. 1989; 50(3-4): 237-251.
  11. Piston DW, Bilash T, Gratton E.
    Compartmental analysis approach to fluorescence anisotropy: perylene in viscous solvents.
    J Phys Chem. 1989; 93(10): 3963-3967.
  12. Cardiel G, Barcellona ML, Gratton E.
    Polydeoxynucleotides/DAPI interactions: a fluorescence study by multifrequency phase fluorometry.
    Ital J Biochem. 1989; 38(2): 125-129.
  13. Bismuto E, Irace G, Gratton E.
    Multiple conformational states in myoglobin revealed by frequency domain fluorometry.
    Biochemistry. 1989; 28(4): 1508-12.

1988

  1. Schroeder F, Nemecz G, Gratton E, Barenholz Y, Thompson TE.
    Fluorescence properties of cholestatrienol in phosphatidylcholine bilayer vesicles.
    Biophys Chem. 1988; 32(1): 57-72.
  2. Valentino M, Governa M, Gratton E, Fiorini R, Curatola G, Bertoli E.
    Increased membrane heterogeneity in stimulated human granulocytes.
    FEBS Lett. 1988; 234(2): 451-4.
  3. Careri G, Gratton E, Shyamsunder E.
    Fine structure of the amide I band in acetanilide.
    Phys Rev A. 1988; 37(10): 4048-4051.
  4. Fiorini R, Valentino M, Glaser M, Gratton E, Curatola G.
    Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene reveal the effect of cholesterol on the microheterogeneity of erythrocyte membrane.
    Biochim Biophys Acta. 1988; 939(3): 485-92.
  5. Thompson RB Gratton E.
    Phase fluorometric method for determination of standard lifetimes.
    Anal Chem. 1988; 60(7): 670-4.
  6. Bismuto E, Gratton E, Irace G.
    Effect of unfolding on the tryptophanyl fluorescence lifetime distribution in apomyoglobin.
    Biochemistry. 1988; 27(6): 2132-6.

1987

  1. Rosato N, Finazzi-Agrò A, Gratton E, Stefanini S, Chiancone E.
    Time-resolved fluorescence of apoferritin and its subunits.
    J Biol Chem. 1987; 262(30): 14487-91.
  2. Fiorini R, Valentino M, Gratton E, Bertoli E, Curatola G.
    Erythrocyte membrane heterogeneity studied using 1,6-diphenyl-1,3,5-hexatriene fluorescence lifetime distribution.
    Biochem Biophys Res Comm. 1987; 147(1): 460-6.
  3. Eccleston JF, Gratton E, Jameson DM.
    Interaction of a fluorescent analog of GDP with elongation factor Tu: steady-state and time-resolved fluorescence studies.
    Biochemistry. 1987; 26(13): 3902-7.
  4. Jameson DM, Gratton E, Eccleston JF.
    Intrinsic fluorescence of elongation factor Tu in its complexes with GDP and elongation factor Ts.
    Biochemistry. 1987; 26(13): 3894-901.
  5. Fiorini R, Valentino M, Wang S, Glaser M, Gratton E.
    Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene in phospholipid vesicles.
    Biochemistry. 1987; 26(13): 3864-70.
  6. Bismuto E, Irace G, Colonna G, Jameson DM, Gratton E.
    Dynamic aspects of the heme-binding site in phylogenetically distant myoglobins.
    Biochim Biophys Acta. 1987; 913(2): 150-4.
  7. Alcala JR, Gratton E, Prendergast FG.
    Interpretation of fluorescence decays in proteins using continuous lifetime distributions.
    Biophys J. 1987; 51(6): 925-36. PMCID: PMC1330026
  8. Schroeder F, Barenholz Y, Gratton E, Thompson TE.
    A fluorescence study of dehydroergosterol in phosphatidylcholine bilayer vesicles.
    Biochemistry. 1987; 26(9): 2441-8.
  9. Bismuto E, Jameson DM, Gratton E.
    Dipolar relaxations in glycerol: a dynamic fluorescence study of 4-[2'-(dimethylamino)-6'-naphthoyl]cyclohexanecarboxylic acid (DANCA).
    J Am Chem Soc. 1987; 109(8): 2354-2357.
  10. Parasassi T, Conti F, Gratton E, Sapora O.
    Membranes modification of differentiating proerythroblasts. Variation of 1,6-diphenyl-1,3,5-hexatriene lifetime distributions by multifrequency phase and modulation fluorimetry.
    Biochim Biophys Acta. 1987; 898(2): 196-201.
  11. Alcala JR, Gratton E, Prendergast FG.
    Fluorescence lifetime distributions in proteins.
    Biophys J. 1987; 51(4): 597-604. PMCID: PMC1329931
  12. Alcala JR, Gratton E, Prendergast FG.
    Resolvability of fluorescence lifetime distributions using phase fluorometry.
    Biophys J. 1987; 51(4): 587-96. PMCID: PMC1329930