Laboratory for Fluorescence Dynamics

A NIH research center for biomedical fluorescence spectroscopy at the University of California, Irvine

Patents

by staff and students of the Laboratory for Fluorescence Dynamics (LFD).

2015

  1. Lanzanò L, Digman MA, Gratton E.
    Nanometer-scale optical imaging by the Modulation Tracking (MT) method.
    Patent US9110282, 18 Aug 2015.
  2. Zhao W, Kang Dk, Zhang K, Ali MM, Eckert MA, Li F, Gratton E, Digman MA, Labanieh L, Lu M.
    Encapsulated sensors and sensing systems for bioassays and diagnostics and methods for making and using them.
    Patent WO2015048173, 30 Apr 2015.

2014

  1. Cutrale F Gratton E.
    Apparatus and method for an inclined single plane imaging microscope box (ispim box).
    Patent US20140320601, 30 Oct 2014.
  2. Gratton E, Dvornikov AS, Crosignani V.
    Apparatus and method for light emission detection for in-depth imaging of turbid media.
    Patent US8692998, 08 Apr 2014.

2012

  1. Gratton E D'Amico E.
    System and method for digital parallel frequency fluorometry.
    Patent US8330123, 11 Dec 2012.
  2. Stringari C, Gratton E, Digman MA, Donovan P.
    Phasor method to fluorescence lifetime microscopy to discriminate metabolic state of cells in living tissue.
    Patent US20120276578, 01 Nov 2012.
  3. Gratton E, Azartash K, Marsili L.
    Method and device for tear film analysis.
    Patent US8256898, 12 Sep 2012.

2009

  1. Gratton E, Motolese G, Tahari AK.
    Methods and devices for characterizing particles in clear and turbid media [continuation of US patent 7528384].
    Patent US20090230324, 17 Sep 2009.
  2. Gratton E, Motolese G, Tahari AK.
    Methods and devices for characterizing particles in clear and turbid media.
    Patent US7528384, 05 May 2009.

2008

  1. Gatto R, D'Amico E, Mantulin WW, Gratton E, Charbel FT.
    Optical microprobe for blood clot detection.
    Patent US20080300493, 04 Dec 2008.
  2. Gratton E, Kukreti S, Cerussi AE, Tromberg BJ.
    Method and apparatus for the determination of intrinsic spectroscopic tumor markers by broadband-frequency domain technology.
    Patent US20080009748, 10 Jan 2008.

2004

  1. Barbieri BB Gratton E.
    Rapid high throughput spectrometer and method [Division of US patent 6603546].
    Patent US6794659, 21 Sep 2004.

2003

  1. Barbieri BB Gratton E.
    Rapid high throughput spectrometer and method.
    Patent US6603546, 05 Aug 2003.

2001

  1. Franceschini MA, Fantini S, Gratton E.
    Method for measuring absolute saturation of time-varying and other hemoglobin compartments.
    Patent US6216021, 10 Apr 2001.
  2. Gratton E, Fantini S, Franceschini MA, Mantulin WW, Barbieri BB.
    Photosensor with multiple light sources.
    Patent US6192261, 20 Feb 2001.

1998

  1. Dong CY, Gratton E, So PTC.
    Pump probe cross correlation fluorescence frequency domain microscope and microscopy.
    Patent US5814820, 29 Sep 1998.
  2. Gratton E, Fantini S, Franceschini MA, Mantulin WW, Barbieri BB.
    Photosensor with multiple light sources [Continuation-in-part of US patents 5497769 and 5492118].
    Patent US5772587, 30 Jun 1998.

1996

  1. Gratton E, Fantini S, Franceschini MA, Mantulin WW, Barbieri BB.
    Photosensor with multiple light sources.
    Patent US5497769, 12 Mar 1996.
  2. Gratton E, Maier JS, Franceschini MA, Fantini S, Walker SA.
    Determining material concentrations in tissues.
    Patent US5492118, 20 Feb 1996.

1994

  1. Gratton E, VandeVen MJ, Barbieri BB.
    Time resolved optical array detectors and CCD cameras for frequency domain fluorometry and/or phosphorimetry.
    Patent US5323010, 21 Jun 1994.

1993

  1. Feddersen BA, Gratton E, Piston DW.
    Method and means for parallel frequency acquisition in frequency domain fluorometry.
    Patent US5257202, 26 Oct 1993.
  2. Gratton E, Mantulin WW, VandeVen MJ.
    Frequency domain optical imaging using diffusion of intensity modulated radiation.
    Patent US5213105, 25 May 1993.
  3. Gratton E Barbieri BB.
    High speed cross-correlation frequency domain fluorometry-phosphorimetry.
    Patent US5212386, 18 May 1993.

1989

  1. Gratton E.
    Frequency domain cross-correlation fluorometry with phase-locked loop frequency synthesizers.
    Patent US4840485, 20 Jun 1989.