Current
Address
|
|
|
University
of California, Irvine |
Telephone:
949/824-2674 |
Doctorate degree: Physics,
Thesis: "The acid denaturation of DNA" (Advisor: Professor Mario
Ageno).
2006-present:
Professor, Department of Biomedical Engineering, UCI
2006-present:
Adjunct Professor, Department of Physics, Univ. of Illinois, Urbana-Champaign
(UIUC)
1986-present:
Principal Investigator and Director, Laboratory for Fluorescence Dynamics
1989-2006:
Professor, Departments of Physics and Biophysics, UIUC
1984-1989:
Associate Professor, Department of Physics, UIUC
1978-1984:
Assistant Professor, Department of Physics, UIUC
1976-1978:
Research Associate, Biochemistry Department (advisor: Gregorio Weber), UIUC
1971-1977:
Researcher, SNAM PROGETTI, Monterotondo, Italy
1970: Fellowship, Instituto Superiore di
Sanita Rome (advisor: Prof. Mario Ageno)
Research
Areas:
Protein Aggregation
Membrane interactions
Migration of cells
Tracking moving particles
Analyzing collagen formation and
deformation
Noninvasive optical technology
methods for studying breast cancer
Consulting Activities:
2007 – 2009: Allergan, Inc. Irvine, CA
2006: Pacific Biosciences, Menlo Park, CA
2005:
Awarded the "6th Annual MSPAC Outstanding Advisor Award" by
the Medical Scholars
Program
Advisory Committee of the University of Illinois at Urbana-Champaign,
8/11/2005.
2005: Awarded the "Gregorio Weber Award for
Excellence in Fluorescence Theory and Application" by the Biological
Fluorescence Subgroup, Long Beach, CA.
2003:
Listed on "Incomplete List of Teachers Ranked as Excellent by their
Students," for Spring Semester, Physics 101: General Physics.
1991:
American Physical Society, Fellow
1991-1992:
Associate in the Center for Advanced Study
1987-1988:
University of Illinois, Xerox Award for Faculty Research, April 1988.
Editorial Boards:
Biophysical Journal, 2003-Present.
Journal of Fluorescence, 1992-97
Comments On Molecular and Cellular Biophysics,
1995-96.
University of California,
Irvine
Winter 2006
BME 297 – PhD Dissertation
Research
Spring 2006
BME 297 – PhD Dissertation
Research
Fall 2006
BME 297 – PhD Dissertation
Research
Winter 2007
BME 195/295 – Spectroscopy
& Imag Bio System (undergraduate
& graduate)
BME 297 – PhD Dissertation
Research
BME 299 – Individual Research
Spring 2007
BME 170 – Biomedical
Engineering Lab (undergraduate)
BME 297 – PhD Dissertation
Research
Fall 2007
BME 195/295 –
Bio-Spectroscopy (undergraduate &
graduate)
BME 297 – PhD Dissertation
Research
BME 299 – Individual Research
Winter 2008
BME 297 – PhD Dissertation
Research
BME 299 – Individual Research
Spring 2008
BME 170 – Biomedical
Engineering Lab (undergraduate)
BME 299 – Individual Research
Fall 2008 (In Progress)
BME 195/295 –
Bio-Spectroscopy (undergraduate &
graduate)
BME 299 – Individual Research
University Service
Departmental Committees (Biomedical Engineering
Faculty Awards Committee, Chair (2007-2009)
Faculty Recruitment Committee, Assistant - Associate
Positions, Chair (2007-2008)
Retreat Planning Committee,
member (2008-2010)
Teaching/Advising/Supervising:
Undergraduate Students:
Current
1.
Lingjie Weng
(2008)
Past
1.
Francesco Cutrale
(2008)
2.
Amanda Napier
(2007-2008)
3. Jaime
Schmieg (2007)
4. Cosimo
Arnesano (2007)
5. Elisa
Frasnelli (2006-2007)
6. Giulia
Ossato (2006-2007)
7. Celli
(1999-2001, received Tesi di Laurea in Fisica (Master's equiv), August 2001)
8. S. T. Gammon (1998-1999)
9. J. D. B. Sutin (1997-2000)
Graduate Students:
Current (Expected Graduation Date):
1.
Molly Rossow
(2008)
2.
Kaveh Azartash
(2009)
3.
Giulia Ossato
(2009)
4.
Peter Fwu
5.
Cosimo Arnesano
6.
Ylenia Santoro
Past graduate students
(Year Degree was Completed), present status, if known:
7.
Ryan Colyer
(Ph.D., 2008), currently at UCLA, Los Angeles, CA
8.
Claudia Lee
(Ph.D., 2007), currently at UVP Inc., Upland, CA
9.
Shwayta Kukreti
(Ph.D., 2007), currently in Medical Scholars Program, University of Illinois at
Urbana-Champaign
10.
Kandice Tanner
(Ph.D., 2006), currently at Univ. of California, Berkeley
11.
Anna Celli
(2006), currently at Veterans Affairs Medical Center, UCSF
12.
D. Eckhoff
(Ph.D., 2006), currently at Webster University, St. Louis, MO
13.
Chiara Polzonetti
(M.S., 2006)
14.
Abdel Tahari
(2005), currently finishing Medical Scholars Program, UIUC*
15.
Natalia Machado
(M.S., 2005)
16.
Jee-Hyun Choi
(Ph.D., 2003), currently at Samsung Advanced Institute of Technology, South
Korea
17.
John Eid (Ph.D.,
2003), currently at Rowland Institute at Harvard, Cambridge, MA
18.
Osman Akcakir
(Ph.D., 2002), currently at Molecular Biology Consortium, Chicago, IL
19.
L. Adelina
Paunescu (Ph.D., 2001), currently at MIT, Cambridge, MA
20.
Timothy Ragan
(Ph.D., 2001), currently at MIT, Cambridge, MA
21.
Claudia Casavola
(2000-Italian doctorate), currently in Italy
22.
Matthia Filiaci
(Ph.D., 2000), currently at Rutter Associates, NY
23.
Yan Chen (Ph.D.,
1999), currently at University of Minnesota
24.
Albert Cerussi
(Ph.D., 1999), currently at Beckman Institute, CA
25.
Scott Walker *
(Ph.D., 1998; M.D., 2001), currently at University of Colorado Health Sciences
Center
26.
Chen-Yuan Dong (Ph.D.,
1997), currently at National Taiwan University, Republic of China
27.
J. Maier* (Ph.D.,
1997), currently at Chemimage Corp, PA
28.
Todd French
(Ph.D., 1996), currently at Molecular Devices, Inc., Sunnyvale, CA
29.
Keith Berland
(Ph.D., 1995), currently at Emory University, GA
30.
Jenny Carrero
(Ph.D., 1994), currently at Unilever, NY
31.
Joshua Fishkin
(Ph.D., 1994), currently at Boeing, Los Angeles, CA
32.
Brett Feddersen
(Ph.D., 1993), currently at Frasca, Champaign, IL
33.
Norberto Silva
(Ph.D., 1993), currently at Mayo Clinic, Rochester, NY
34.
J. L. Vittitow (Ph.D., 1990)
35.
David W. Piston
(Ph.D., 1989), currently at Vanderbilt University, Nashville, TN
36.
S. L. Lin (Ph.D.,
1988)
37.
Jose R. Alcala (Ph.D., 1987), deceased
38.
M. K. Limkeman
(Ph.D., 1984), currently at Milwaukee GE Medical Center, WI
39.
C. J. Hardy
(Ph.D., 1983), currently at Medical Center Schenckdidy, NY
*Medical Scholars Program
Research Associates (Post-doctorate):
Current
1. Luca Lanzano (2008-)
Past
2.
Kandice Tanner
(2007-2008), currently at Univ. of California, Berkeley
3.
Enrico D'Amico
(2002-2007), currently at Univ. of California, Irvine
4.
Michelle Digman
(2003-2008), currently at Univ. of California, Irvine
5. Christian Hellriegel
(2006-2008), currently at Fundacion Centro Nacional de Investigaciones
Cardiovasculares Carlos III, Madrid, Spain
6. Jay Unruh (2006-2008), currently at Stowers Institute
for Medical Research, Kansas City, MO
7. Nicholas Barry (1997-2003), currently
at Univ. of Colorado, Health Sciences Ctr, Denver
8. Joseph M. Beechem (1987-89),
currently at Molecular Probes, Oregon
9. Luis A. Bagatolli (1997-00),
currently at University of Southern Denmark
10. Christof Buehler (1996-98), currently
at Paul Schrerrer Institute, Switzerland
11. Mateo Calderon-Arnulphi (2002-05),
currently at University of Illinois at
Chicago
12. Yan Chen (1998-00), currently at
University of Minnesota
13. Andrea
De Oliveira (2003-2006), currently at Universida de Federal do Rio de Janeiro,
Brazil
14. Svante Eriksson (1992-93)
15. Sergio Fantini (1993-96), currently at
Tufts University, Massachusetts
16. Mari A. Franceschini (1993-99),
currently at Massachusetts General Hospital
17. Katerina Kis-Petikova (1999-2001),
currently at Institute of Biophysics & Radiation Biology, Budapest, Hungary
18. Valeria Levi (2003-2006), currently
at University of Buenos Aires, Argentina
19. Jochen Müller (1997-00), currently at
University of Minnesota
20. Gina Perez (2002), currently at Vanderbilt University Medical Center
21. Qiaoqiao Ruan (2003-2004), currently
at Abbott Labs, Illinois
22. Cathy A. Royer (1988-91), currently
at CNRS, France
23. Larissa
P. Safonova (2000-2003), currently in Russia
24. Parijat, Sengupta (2004-), currently
at SUNY Stony Brook, NY
25. Peter T. C. So (1992-96), currently
at Massachusetts Institute of Technology
26. Allain Sillen (1999-2002)
27. Martin Wolf (1998-2001)
28. Ursula Wolf (1999-2001)
29. Weiming Yu (1997-2000), currently at
Indiana University
Visiting
Scholars (more than 6 months):
1. Paul Wiseman (2007-2008)
2. Andre M. O. Gomes (2003)
3. Wooseok Ko (2004)
Research
Technicians:
1. Ben Pruess (2008-)
2. Jennifer Sasaki (2007-present)
3. Christine M. Larson (1991-1997)
4. Ruth M. Rusch (1987-1990)
Visiting Scholars (more than 6
months)
1. Paul Wiseman
(2007-2008), currently at McGill University, Montreal, QC, Canada
Extramural Support:
Active:
Pending:
Book Chapters:
Published:
B-1Gratton, E. and R. Lopez-Delgado.
Remarks on a novel method for fluorescence lifetime measurements. In Time Resolved Fluorescence
Spectroscopy in Biochemistry and Biology (R. B. Cundall and R. E. Dale,
Eds.) NATO ASIS, Ser. A. Vol. 69A, Plenum Press, NY, pp. 109-114 (1983).
B-2Jameson, D. and E. Gratton. Analysis of
heterogeneous emissions by multifrequency phase and modulation fluorometry. In New Directions in Molecular
Luminescence. ASTM-STP 822 (D. Eastwood, Ed.) (American Society of Testing
and Materials), pp. 67-81 (1983).
B-3Careri, G. and E. Gratton. The statistical
time correlation approach to enzyme action: The role of hydration. In The Fluctuating Enzyme, Ch. X,
pp. 227-262 (G. R. Welch, Ed.) Wiley & Sons, NY (1984).
B-4Gratton,
E., J. R. Alcala and G. Marriott. Rotational motions of tryptophan and
tyrosine residues in proteins. In Structure
and Dynamics of Nucleic Acids, Proteins, and Membranes (E. Clementi and S.
Chin, Eds.) 149-151 (1986).
B-5Gratton,
E., N. Silva and S. Ferreira. Fluorescence of tryptophan and
protein dynamics. In Biological
and Artificial Intelligence Systems (E. Clementi and S. Chin, Eds.) 49-55
(1988).
B-6Lentz, B. R., S. W. Burgess and E.
Gratton. Concentration dependence of DPHpPC fluorescence lifetime: Photophysics
and utility for monitoring membrane fusion. In
Molecular Mechanisms of Membrane Fusion (S. Ohki, D. Doyle, T. D.
Flanagan, S. W. Hue and E. Mayhew, Eds.) Plenum Pub. Corp. (1988).
B-7Gratton, E., J. R. Alcala and F. G.
Prendergast. Protein dynamics: Fluorescence lifetime distributions. In Fluorescent Biomolecules, pp.
17-32 (D. M. Jameson and G. Reinhart, Eds.) Plenum Press (1989).
B-8Gratton, E. and M. J. vandeVen. Laser
sources for confocal microscopy. In The
Handbook of Biological Confocal Microscopy (J. Pawley, Ed.) Ch. 5, pp.
53-67. Plenum Press, Proc. EMSA 47th Annual Mtg., San Antonio, TX (1990).
B-9Gratton,
E., J. R. Alcala and B. Barbieri. Frequency domain fluorometry. In Handbook of Luminescence
Techniques in Chemical and Biochemical Analysis (W.R.G. Baeyens, D. De
Keukeleire and K. Korkidis. Eds.) Marcel Dekker, Inc., pp. 47-72 (1991).
B-10
Beechem,
J. M., E. Gratton, M. Ameloot, J. R. Knutson and L. Brand. The global analysis
of fluorescence intensity and anisotropy decay data: Second generation theory
and programs. In Topics in
Fluorescence Spectroscopy, II "Principles." (J. R. Lakowicz, Ed.)
Ch. 5, pp. 241-305 (1991).
B-11
Parasassi, T., M. Di Stefano, G.
Ravagnan, O. Sapora and E. Gratton. Membrane aging
during cell growth ascertained by Laurdan generalized polarization. In Experimental Cell Research 202,
Academic Press, 432-439 (1992).
B-12
Ferreira,
S. T. and E. Gratton. Enzyme activity in reverse micelles: Roles of diffusion
and extent of hydration. In Biomolecules
in Organic Solvents, CRC Meeting, Ch. 8, pp. 189-201 (1992).
B-13
Reinhart,
G., E. Gratton and W. Mantulin. Dissociation of large oligomeric proteins by
high hydrostatic pressure: dynamic light scattering studies. NATO ASI Series
Volume "High Pressure Chemistry, Biochemistry and Materials
Sciences." (R. Winter, Ed.), 619-626 (1993).
B-14
vandeVen, M. and E. Gratton. Time-resolved
fluorescence lifetime imaging. In Optical
Microscopy: Emerging Methods and Applications, Academic Press, Ch. 14,
373-402 (1993).
B-15
Gratton,
E. and M. J. vandeVen. Laser sources for confocal microscopy. In The Handbook of Biological Confocal
Microscopy, Second Edition (J. Pawley, Ed.) Plenum Press Ch. 5 pp. 69-97
(1995).
B-16
So,
P. T. C., T. French, W. M. Yu, K. M. Berland, C. Y. Dong, and E. Gratton. Two
photon microscopy: Time-resolved and intensity imaging. In Fluorescence Imaging Spectroscopy and Microscopy (Wang,
X. F. and B. Herman, Eds.) Chemical Analysis Series, Vol. 137, John Wiley &
Sons, Inc., Ch. 11, 351-374 (1996).
B-17
French,
T., P. T. C. So, C. Y. Dong, K. M. Berland and E. Gratton. Fluorescence
lifetime imaging techniques for microscopy.
In "Methods in Cell Biology." Video Microscopy. Greenfield
Sluder and David Wolf, Eds., Vol. 56, pp. 227-304 (1997).
B-18
Fantini, S., B. Barbieri, M. A.
Franceschini and E. Gratton. Frequency-domain spectroscopy. In Applications of Optical Engineering
to the Study of Cellular Pathology, E. Kohen, ed., (Research Signpost,
Trivandum, India), pp. 57-66 (1997). [abstract]
B-19
So,
P. T. C., C. Y. Dong, K. M. Berland, T. French and E. Gratton. Time-resolved
stimulated-emission and transient-absorption microscopy and spectroscopy. In Topics in Fluorescence
Spectroscopy, Vol. 5: Nonlinear and Two-Photon-Induced Fluorescence, Chapter
10. Plenum Press, NY. Ed., J. R. Lakowicz, pp. 427-469 (1997).
B-20
Fantini,
S., S. A. Walker, M. A. Franceschini, K. T. Moesta, P. M. Schlag, M. Kaschke,
and E. Gratton. Optical characterization of breast tumors by frequency-domain
optical mammography, OSA Trends in Optics and Photonics Series 21, Eds.,
James G. Fujimoto and Michael S. Patterson, 143147 (1998).
B-21
Franceschini,
M. A., A. Paunescu, S. Fantini, S. Pratesi, J. S. Maier, G. P. Donzelli, and G.
Gratton, Frequency-domain optical measurements in vitro on two- and
three-layered tissue-like phantoms, and in vivo on infant heads, OSA Trends
in Optics and Photonics Series 21, Eds., James G. Fujimoto and Michael S.
Patterson, 232-236 (1998).
B-22
Paunescu,
A., M. A. Franceschini, S. Fantini, A. Cerussi, and E. Gratton, Effective
optical properties of two-layered turbid media using the frequency-domain
multi-distance method, OSA Trends in Optics and Photonics Series 21,
Eds., James G. Fujimoto and Michael S. Patterson, 79-83 (1998).
B-23
Toronov,
V., M. Filiaci, S. Fantini, and E. Gratton, Study of large scale fluctuations
in turbid media by photon-density-wave fluctuation correlation spectroscopy, OSA
Trends in Optics and Photonics Series 21, Eds., James G. Fujimoto and
Michael S. Patterson, 60-62 (1998).
B-24
So,
P. T. C., B. R. Master, E. Gratton, and I. E. Kochevar, Two-photon optical
biopsy of thick tissues, OSA Trends in Optics and Photonics Series 22,
Eds., Eva M. Sevick-Muraca, Joseph A. Izatt, and Marwood N. Ediger, 40-42
(1998).
B-25
Filiaci,
M., V. Toronov, S. Fantini, and E. Gratton, Optical probe and frequency-domain
instrumentation to study spatial and temporal correlations of fluctuations in
tissues, OSA Trends in Optics and Photonics Series 22, Eds., Eva M.
Sevick-Muraca and Joseph A. Izatt, 183-187 (1998).
B-26
Masters,
B. R., P. T. C. So, W. W. Mantulin, and E. Gratton, Tissue Microscopy and
Spectroscopy: A Two-Photon Approach, OSA Trends in Optics and Photonics
Series 22, Eds., Eva Sevick-Muraca, Joseph A. Izatt, and Marwood N. Ediger,
43-45 (1998).
B-27
Cerussi,
A., S. Fantini, and E. Gratton, Quantitative fluorescence spectroscopy in
strongly scattering media containing multiple fluorophores, OSA Trends in
Optics and Photonics Series 22, Eds., Eva M. Sevick-Muraca, Joseph A. Izan,
and Marwood N. Ediger, pp. 70-75 (1998).
B-28
Chen, Y., J. D. Müller, K. M. Berland,
and E. Gratton. Fluorescence Fluctuation
Spectroscopy, In Confocal
Microscopy: Methods in Enzymology 19(2) eds. P. Michael Conn, (Academic
Press), pp.
234-252 (1999).
B-29
Masters,
B. R., P. T. C. So, and E. Gratton. Multiphoton
excitation microscopy and spectroscopy of cells, tissues and human skin in
vivo. Fluorescent and Luminescent Probes for Biological Activity. Biological
Techniques Series 2, ed. W. T. Mason, 416-432 (1999).
B-30
Gratton,
E. Laser sources for confocal and two-photon microscopy. In Confocal and Two-Photon Microscopy: Foundations, Applications
and Advances. A. Diaspro, ed., Wiley & Sons, Inc. (2000).
B-31
Yu,
W., W. W. Mantulin, and E. Gratton. Fluorescence Lifetime Imaging: New
Microscopy Technologies. In: Emerging
Tools for Single-Cell Analysis, G. Durack and J. P.Robinson, eds.
(Wiley-Liss, Inc.), pp. 139-173 (2000).
B-32
Müller,
J. D., Y. Chen, and E. Gratton. Photoncounting histogram statistics. In: Fluorescence Correlation
Spectroscopy. Theory and Applications, E. L. Elson and R. Rigler, eds.
(Springer Publishers) Ch. 20, pp. 410-435 (2001).
B-33
Muller,
J., Y. Chen, and E. Gratton. Fluorescence Correlation Spectroscopy. In: Methods in Enzymology 361,
Ch. 4, pp. 69-92, G. Marriott and I. Parker, eds. (2003).
B-34
Dong
CY, T. French, P. T. So, C. Buehler, K. M. Berland and E. Gratton. Fluorescence-lifetime imaging techniques for
microscopy. In: Methods Cell
Biol., 2nd Edition, G. Sluder and D. E. Wolf, eds., Vol. 72, pp.
431-64(2003).
B-35
Bagatolli,
L. A., S. Sanchez, T. Hazlett and E. Gratton. Giant vesicles, Laurdan, and
two-photon fluorescence microscopy: evidence of lipid lateral separation in
bilayers. In: Methods of
Enzymology 360, Ch. 20, pp 481-500, G. Marriott, ed. (2003).
B-36
Gratton,
E. and S. Fantini. Reflectance and Transmittance Spectroscopy. In Laser and Current Optical
Techniques in Biology, Vol. 4, Ch. 11,
R. Pratesi and G. Palumbo, eds. pp. 211-258 (2004).
B-37
Gratton, E., S.
Breusegem, N. Barry, Q. Ruan, and J. Eid. Fluctuation correlation
spectroscopy in cells: Determination of molecular aggregation. Chapter 1 in: Biophotonics-Optical Science and
Engineering for the 21st Century, Kluwer Academic/Plenum Publishers. Shen,
X. Van Wijk, R.;(Eds.) XVIII, pp. 1-14. ISBN:
0-387-24995-8 (2005).
B-38
S A
Sánchez, M A Tricerri, G Gunther, and E Gratton. Laurdan generalized polarization: from cuvette to microscope. In Modern Research and Educational Topics in Microscopy. Vol.
2: Applications in Physical/Chemical Sciences
(Microscopy Book Series, Vol. 3). By A Méndez-Vilas and J Díaz (Editors). Formatex Research Center, Badajoz, Spain, pp.
1007-1014 (2007). ISBN: 9788461194209
B-39
A
Celli, C Y Lee, and E Gratton. Fluorescence microscopy to study pressure between
lipids in giant unilamellar vesicles. In Methods in Membrane Lipids
(Methods in Molecular Biology, Vol. 400).
By AM Dopico (Editors). Humana Press, pp.
333-340 (2007). ISBN: 1588296628
B-40
M A Digman and E
Gratton. The
RICS method: measurement of fast dynamics in cells with the laser scanning
microscope. In Image Analysis in Medical
Microscopy and Pathology. By HS Wu and AJ Einstein (Editors). Research Signpost,
Kerala, pp. 207-224 (2007). ISBN: 8130801167
B-41
V Levi and E Gratton. 3-Dimensional
particle tracking in a laser scanning fluorescence microscope. In Single-particle tracking and single molecule energy
transfer. By C Bräuchle, DC Lamb, and J Michaelis
(Editors). Wiley VCH (2008). ISBN: 9783527322961 [accepted].
B-42
E
Gratton, V Toronov, U Wolf and M Wolf. Detection of Brain Activity by
Near-Infrared Light. In Biomedical Optical Imaging.
By D Farkas and J G Fujimoto (Editors). Oxford University Press. (2009).
[accepted].
Journal Articles:
Published:
J-1 Gratton, E. The Acid Denaturation
of DNA.
Rap. 1st. Sup. San. 155, 46 pp.
(1971).
J-2 Grandolfo,
M., E. Gratton, F. Anfosso Somma and P. Vecchia. Exciton binding energies of layer-type semiconductors
GaSe and GaTe.
Phys. Stat. Sol.(b) 48, 729-735 (1971).
J-3 Gratton, E. Method for the automatic correction of scattering in
absorption spectra by using the integrating sphere. Biopolymers
10, 2629-2634 (1971).
J-4 Dore,
E., C. Frontali and E. Gratton. The role of ions in the acid melting of DNA. Biopolymers
11, 2033-2041 (1972).
J-5 Dore,
E., C. Frontali and E. Gratton. Physico-chemical description of a condensed form of
DNA.
Biopolymers 11, 443-459 (1972).
J-6 Cancellieri,
A., C. Frontali and E. Gratton. Dispersion effect on turbidimetric size measurements. Biopolymers
13, 735-743 (1974).
J-7 Gentile,
S. and E. Gratton. Misure di Costante Dielettrica su polveri di lisozima
idratato. Rap.
Ist. Fis. Roma
561 (1974).
J-8 Careri,
G., P. Fasella and E. Gratton. Statistical time events in enzymes: A physical assessment. Crit.
Rev. Biochem. 3, 141-164 (1975).
J-9 G.
Careri, A. Giansanti and E. Gratton, Eds. Studio I.R. dell'idratazione del
lisozima. Rap.
Ist. Fis. Roma
(1977).
J-10
Giannini,
L. and E. Gratton. Hydration of globular proteins: U.V. studies. Rend. Acc. Naz. Lincei. Sci. Fis. Mat. Natl.
62, 711-715 (1977).
J-11
Careri, G., L. De Angelis, E. Gratton
and C. Messana. Magnetic susceptibility of lysozyme. Phys.
Lett. 60A, 490-491 (1977).
J-12
Careri, G. and E.
Gratton. Onsager
coupling in enzymes. Biosystems 8, 185-186 (1977).
J-13
Ascoli, F., E. Gratton, F. Riva, P.
Fasella and M. Brunori. Infrared stretching frequencies of CO in
carbomonoxyhemoglobin from trout.
Biochim. Biophys. Acta 553, 534-537
(1978).
J-14
Gratton,
E. and R. Lopez-Delgado. The harmonic content of a SR pulse: The possibility to
reach subpicosecond resolution in the fluorescence decay experiment. SSRL Report No. 78/09 (1978).
J-15
Gratton,
E. and R. Lopez-Delgado. Use of synchrotron radiation for the measurement of
fluorescence lifetimes with subpicosecond resolution. Rev.
Sci. Inst. 50, 789-790 (1979).
J-16
Careri, G., P. Fasella and E. Gratton. Enzyme
dynamics: The statistical physics approach. Ann.
Rev. Biophys. and Bioeng. 8, 69-97 (1979).
J-17
Careri, G., A. Giansanti and E. Gratton.
Lysozyme film hydration events--An IR and gravimetric
study.
Biopolymers 18, 1187- 1203 (1979).
J-18
Frontali, C., E. Dore, A. Ferrauto, E.
Gratton, A. Bettini, M. R. Pozzan and E. Valdevit. An absolute
method for the determination of the persistence length of native DNA from
electron micrographs.
Biopolymers 18, 1353-1373 (1979).
J-19
Gratton,
E. Hydration induced mobility in azurin. Proc. of the III Intl. Conf. "De la Physique Theorique a
la Biologie"
Springer, Vienna, July (1979).
J-20
Gratton,
E. The time
dimension of protein systems.
Adv. Physiol. Sci. 3, 269-273 (1980).
J-21
Gratton,
E. and R. Lopez-Delgado. Measuring fluorescence decay times by phase-shift and
modulation techniques using the high harmonic content of pulsed light sources. I1
Nuovo Cimento 56B, 110-124 (1980).
J-22
Careri,
G., E. Gratton, P.-H. Yang and J. A. Rupley. Correlation of IR spectroscopic, heat capacity,
diamagnetic susceptibility and enzymatic measurements on lysozyme powder. Nature
284, 572-573 (1980).
J-23
Careri, G., A. Giansanti and E. Gratton.
Molecular aspects of the hydration process in a
globular protein.
Int. J. Quantum Chem. Vol. XIX, pp.
1133-1135 (1981).
J-24
Gratton,
E. and M. Limkeman. A continuously
variable frequency cross-correlation phase fluorometer with picosecond
resolution.
Biophys. J. 44, 315-324 (1983).
J-25
Careri, G., U. Buontempo, F. Carta, E.
Gratton and A. Scott. Infrared absorption in acetanilide by solitons. Phys.
Rev. Lett. 51(4), 304-307 (1983).
J-26
Gavish,
B., E. Gratton, C. J. Hardy and A. St. Denis. Differential sound velocity apparatus for the
investigation of protein solutions. Rev.
Sci. Inst. 54, 1756-1760 (1983).
J-27
Gratton,
E. and M. Limkeman. Microprocessor-controlled
photon-counting spectrofluorometer. Rev.
Sci. Inst. 54(3), 294-299 (1983).
J-28
Gratton, E., N. Rosato, D. M. Jameson,
F. Antonangeli, F. Bassani, F. Campolungo, U. Grassano, A. Finazzi-Agró, M.
Piacentini A. Savoia, G. Weber and N. Zema. A
multifrequency phase-fluorometer with picosecond resolution using synchrotron
radiation. INFN-PULS Frascati Report,
65 pp. (1983).
J-29
Rupley,
J. A., E. Gratton and G. Careri. Water and globular proteins. Trends
in Biochem. 8, 18-22 (1983).
J-30
Gavish,
B., E. Gratton and C. J. Hardy. Adiabatic
compressibility of globular proteins. Proc. Natl. Acad. Sci. USA 80,
pp. 750-754 (1983).
J-31
Lakowicz,
J. R., E. Gratton, H. Cherek and B. P. Maliwal. Frequency-domain phase-modulation fluorometry:
Resolution of complex decays of fluorescence intensity and anisotropy.
J. of Lumin. 31&32, 699-702 (1984).
J-32
Parasassi, T., F. Conti, M. Glaser and
E. Gratton. Detection of phospholipids phase
separation. A multifrequency phase fluorimetry study of 1,6-diphenyl-1,3,5-hexatriene
fluorescence.
J. Biol. Chem. 259(22), 14011-14017
(1984).
J-33
Lakowicz,
J. R., H. Cherek, G. Laczko and E. Gratton. Time-resolved fluorescence emission spectra of labeled
phospholipid vesicles, as observed using multifrequency phase fluorometry. Biochim.
Biophys. Acta 777, 183-193 (1984).
J-34
Lakowicz,
J. R., E. Gratton, H. Cherek, B. P. Maliwal and G. Laczko. Determination of time-resolved fluorescence emission
spectra and anisotropies of a fluorophore-protein complex using frequency-
domain phase-modulation fluorometry. J.
Biol. Chem. 259(17), 10967- 10972 (1984).
J-35
Careri, G., U. Buontempo, F. Galluzzi,
A. C. Scott, E. Gratton and E. Shyamsunder. Spectroscopic
evidence for Davydov-like solitons in acetanilide. Phys.
Rev. B 30 (8), 4689-4702 (1984).
J-36
Parasassi, T., F. Conti and E. Gratton. Study of heterogeneous emission of parinaric acid
isomers using multifrequency phase fluorometry. Biochemistry
23(23), 5660-5664 (1984).
J-37
Conti, F., T. Parasassi, N. Rosato, O.
Sapora and E. Gratton. Fluorescence studies using synchrotron radiation on
normal and differentiated cells labeled with parinaric acids. Biochim.
Biophys. Acta 805, 117-122 (1984).
J-38
Gratton,
E., M. Limkeman, J. R. Lakowicz, B. P. Maliwal, H. Cherek and G. Laczko. Resolution of mixtures of
fluorophores using variable-frequency phase and modulation data. Biophys.
J. 46, 479486 (1984).
J-39
Lakowicz,
J. R., G. Laczko, H. Cherek, E. Gratton and M. Limkeman. Analysis of fluorescence decay kinetics from
variable-frequency phase shift and modulation data. Biophys.
J. 46, 463-477 (1984).
J-40
Marque,
J., L. Eisenstein, E. Gratton, J. M. Sturtevant and C. J. Hardy. Thermodynamic properties of purple membrane. Biophys.
J. 46, 567-572 (1984).
J-41
Gratton,
E., D. M. Jameson and R. Hall. Multifrequency phase and modulation fluorometry. Ann.
Rev. Biophys. Bioeng. 13, 105- 124 (1984).
J-42
Jameson,
D. M., E. Gratton and R. Hall. The measurement and analysis of heterogeneous emissions
by multifrequency phase and modulation fluorometry. App.
Spec. Rev. 20, 55-106 (1984).
J-43
Jameson,
D., E. Gratton, G. Weber and B. Alpert. Oxygen distribution and migration within mbdes fe and hbdes fe: multifrequency phase and modulation
fluorometry study.
Biophys. J. 45, 795- 803 (1984).
J-44
Gratton,
E., D. M. Jameson, N. Rosato and G. Weber. Multifrequency cross-correlation phase fluorometer
using synchrotron radiation.
Rev. Sci. Inst. 55, 486-494 (1984).
J-45
Gratton,
E., D. Jameson, G. Weber and B. Alpert. A model of dynamic quenching of fluorescence in globular
proteins.
Biophys. J. 45, 789-794 (1984).
J-46
Alcala,
R., E. Gratton and D. M. Jameson. A multifrequency phase fluorometer using the harmonic
content of a mode-locked laser.
Anal. Inst. 14(3&4), 225-250 (1985).
J-47
Lakowicz,
J. R., B. P. Maliwal and E. Gratton. Recent developments in frequency-domain fluorometry. Anal.
Inst. 14(3&4), 193-223 (1985).
J-48
Mugnier,
J., B. Valeur and E. Gratton. Rate of intramolecular energy transfer in coumarin
bichromophoric molecules. An investigation by multifrequency phase-modulation
fluorometry.
Chem. Phys. Lett. 119 (2&3)
217-222 (1985).
J-49
Scott,
A. C., E. Gratton, E. Shyamsunder and G. Careri. IR overtone spectrum of the vibrational soliton in
crystalline acetanilide.
Phys. Rev. Lett. B 32, 5551-5553
(1985).
J-50
Frauenfelder, H. and E. Gratton. Protein dynamics and hydration. In
Methods in Enzymology 127, "Biomembranes, Protons and Water:
Structure and Translocation." (1985).
J-51
Gratton,
E. and D. M. Jameson. New approach to
phase and modulation resolved spectra. Anal.
Chem. 57, 1694-1697 (1985).
J-52
Lakowicz,
J. R., H. Cherek, B. Maliwal and E. Gratton. Time- resolved fluorescence anisotropies of
diphenylhexatriene and perylene in solvents and lipid bilayers obtained by
multifrequency phase-modulation fluorometry. Biochemistry
24, 376-383 (1985).
J-53
Gratton,
E. and J. R. Lakowicz. Ultrafast dynamics in proteins and membranes by time
resolved fluorescence spectroscopy. In
Structure and Motion: Membranes, Nucleic Acids, and Proteins (E.
Clementi, G. Corongiu, M. H. Sarma and A. R. Sarma, Eds.) Adenine Press, NY,
pp. 155-168 (1985).
J-54
Gratton,
E. and B. Barbieri. Multifrequency
phase fluorometry using pulsed sources: Theory and applications. Spectroscopy
1 (6), 28-36 (1986).
J-55
Gratton,
E., J. R. Alcala, G. Marriott and F. G. Prendergast. Fluorescence studies of protein dynamics. In
Proc. International Symposium of Computer Analysis for Life Sciences.
Progress and Challenges in Biological and Synthetic Polymer Research,
HAYASHIBARA FORUM '85 (C. Kawabata and A. R. Bishop, Eds.) Tokyo, Japan, pp.
1-11 (1986).
J-56
Parasassi, T., F. Conti and E. Gratton. Time-resolved fluorescence emission spectra of Laurdan
in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell.
and Mol. Biol. 32, 103-108 (1986).
J-57
Parasassi, T., F. Conti and E. Gratton. Fluorophores in a polar medium: time dependence of emission
spectra detected by multifrequency phase and modulation fluorometry. Cell.
and Mol. Biol. 32(1), 99-102 (1986).
J-58
Rosato, N., A. Finazzi-Agró, E. Gratton,
S. Stefanini and E. Chiancone. Time-resolved fluorescence of Apoferritin and its
subunits.
J. Biol. Chem. 262, 14487-14491
(1987).
J-59
Glaser, M., E. Gratton, T. Parasassi, O.
Sapora and F. Conti. Spectroscopic investigation of the physical state of
biological membranes using the fluorescence methodology. In
Proc., 2nd Conf. on The State of Art of Research in the Chemistry
Department, La Sapienze, Rome, pp. 293-301 (1987).
J-60
Lentz,
B. R., S. W. Burgess and E. Gratton. Concentration dependence of DPHpPC fluorescence
lifetime: Photophysics and utility for monitoring membrane fusion. In
Proc. of International Symp. on Mole. Mech. of
Membrane Fusion, Buffalo, NY (1987).
J-61
Eccleston,
J., E. Gratton and D. M. Jameson. Interactions of a fluorescence analog of GDP with
elongation factor Tu: steady-state and time resolved fluorescence studies. Biochemistry
26, 39023907 (1987).
J-62
Jameson,
D. M., E. Gratton and J. Eccleston. Intrinsic fluorescence of elongation factor Tu in its
complexes with GDP and elongation factor Tu. Biochemistry
26, 3894-3901 (1987).
J-63
Fiorini,
R., M. Valentino, S. Wang, M. Glaser and E. Gratton. Fluorescence lifetime distributions of 1,6-diphenyl-1-3-5-hexatriene in phospholipid vesicles.
Biochemistry 26, 3864-3870 (1987).
J-64
Alcala,
R., E. Gratton and F. G. Prendergast. Interpretation of fluorescence
decays in proteins using continuous lifetime distributions. Biophys.
J. 51, 925-936 (1987).
J-65
Bismuto,
E., G. Irace, G. Colonna, D. M. Jameson and E. Gratton. Dynamic aspects of the heme binding site in
phylogenetically distant myoglobins. Biochim.
Biophys. Acta 913, 150-154 (1987).
J-66
Schroeder,
F., Y. Barenholz, E. Gratton and T. E. Thompson. A fluorescence study of dehydroergosterol in
phosphatidylcholine bilayers vesicles. Biochemistry
26, 2441-2448 (1987).
J-67
Gratton,
E. and B. Barbieri. Molecular dynamics studies using frequency-domain
fluorometry. SPIE Proc., Vol. 743, 104-109 (1987).
J-68
Parasassi, T., F. Conti, E. Gratton and
0. Sapora. Membranes modifications of differentiating
proerythroblast. Variation of 1,6-diphenyl-1,3,5-hexatriene
lifetime distributions by multifrequency phase and modulation fluorometry. Biochim.
Biophys. Acta 898(2), 196-201 (1987).
J-69
Gratton, E., J. R. Alcala and G.
Marriott. Rotations of tryptophan residues in
proteins. Biochem. Soc. Trans., 617th Meeting, Dundee 14, 835-838
(1987).
J-70
Bismuto,
E., D. M. Jameson and E. Gratton. Dipolar relaxations in glycerol: a dynamic
fluorescence study of 4-2'-(dimethylamino)-6'-naphthoylcyclohexanecarboxylic
acid (DANCA).
J. Am. Chem. Soc. 109, 2354-2357
(1987).
J-71
Alcala,
J. R., E. Gratton and F. G. Prendergast. Fluorescence lifetime distributions in proteins. Biophys.
J. 51, 597-604 (1987).
J-72
Barbieri, B., E. Gratton, W. W.
Mantulin, J. J. Sparrow. Continuous lifetime distributions and
rotations of tryptophan residues in proteins. Thirty-eight Pittsburgh Conf.
& Expo. on Analytical Chem. and Appl. Spec., Atlantic City, NJ, March
8-13, No. 996 (1987).
J-73
Alcala,
R., E. Gratton and F. G. Prendergast. Resolvability of fluorescence lifetime distributions
using phase fluorometry.
Biophys. J. 51, 587-596 (1987).
J-74
Barbieri, B., F. DePicoli and E.
Gratton. Resolution of overlapping spectra
using frequency-domain fluorometry. In Proc.
SPIE 909, Time-Resolved Laser Spectroscopy in Biochemistry. J. R. Lakowicz,
ed., 366-369 (1988).
J-75
Beechem,
J. M. and E. Gratton. Fluorescence spectroscopy data analysis environment: A
second generation Global analysis program. In
Proc. SPIE 909, Time-Resolved Laser Spectroscopy in Biochemistry. J. R.
Lakowicz, ed., 70-81 (1988).
J-76
Schroeder,
F., G. Nemecz, Y. Barenholz, E. Gratton and T. E. Thompson. Cholestatrienol
time resolved fluorescence in phosphatidylcholine bilayers. In Proc. SPIE 909, Time-Resolved
Laser Spectroscopy in Biochemistry. J. R. Lakowicz, ed., 457-465 (1988).
J-77
Bismuto,
E., E. Gratton and G. Irace. Effect of unfolding on the tryptophanyl fluorescence
lifetime distribution in apomyoglobin. Biochemistry
27, 2132-2136 (1988).
J-78
Careri,
G., E. Gratton and E. Shyamsunder. Fine structure of the amide I band in acetanilide. Phys.
Rev. A, 37(10), 4048-4051 (1988).
J-79
Fiorini, R. M., M. Valentino, M. Glaser,
E. Gratton and E. Curatola. Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene reveal the effect of
cholesterol on the microheterogeneity of erythrocyte membrane. Biochim.
Biophys. Acta 939 , 485-492 (1988).
J-80
Valentino, M., M. Governa, E. Gratton,
R. Fiorini, G. Curatola, E. Bertoli. Increased
membrane heterogeneity in stimulated human granulocytes. FEBS
Letters 234(2), 451-454 (1988).
J-81
Schroeder,
F., G. Nemecz, E. Gratton, Y. Barenholz and T. E. Thompson. Fluorescence properties of cholestatrienol in
phosphatidylcholine bilayer vesicles. Biophys.
Chem. 32, 57-72 (1988).
J-82
Thompson,
R. B. and E. Gratton. Phase fluorometric method for determination of
standard lifetimes.
Anal. Chem. 60, 670- 674 (1988).
J-83
Fiorini, R., E. Gratton and G. Curatola.
Effect of cholesterol on membrane microheterogeneity: A study using 1,6-diphenyl-1,3,5-
hexatriene fluorescence lifetime distributions. Biochim.
Biophys. Acta 006 (2), 198-202 (1989).
J-84
Wratten,
M. L., E. Gratton, M. vandeVen and A. Sevanian. DPH lifetime distributions in vesicles containing
phospholipid hydroperoxidides.
BBRC 164 ,
169-175 (1989).
J-85
Barcellona, M. L. and E. Gratton. Fluorescence
lifetime distributions of DNA/4'6-diamidino-2phenylindole complex. Biochim.
Biophys. Acta. 993, 174-178 (1989).
J-86
Barbieri, B. F. DePicoli and E. Gratton.
Synthesizers' phase noise in frequency-domain
fluorometry.
Rev. Sci. Inst. 60, 3201- 3206
(1989).
J-87
Piston,
D. W. and E. Gratton. Orientational
exchange approach to fluorescence anisotropy decay. Biophys.
J. 56., 1083-1091 (1989).
J-88
Gratton,
E. and M. vandeVen. A superheterodyning microwave phase fluorometer with
femtosecond resolution using a microchannel plate. Rev. Sci. Inst. LFD Report 18 (1989).
J-89
Rosato, N., E. Gratton, G. Mei, I.
Savini and A. Finazzi-Agrò. Dynamic fluorescence in copper
proteins: Selected examples. Proc. Satellite FEBS 1989 Symp. Biochem. and Biophys. Approaches to the Study of Copper Proteins,
Camerino, Italy (1989).
J-90
Cardiel, G., M. L. Barcellona and E.
Gratton. Polydeoxynucleotides/DAPI interactions: A fluorescence
study by multifrequency phase fluorometry. The
Italian J. of Biochem. 38, 125-129 (1989).
J-91
Parasassi,
T. and E. Gratton. Detection of phospholipid bilayers microheterogeneity and
domains by fluorescence spectroscopy. Proc. Serono Symposium on Membrane
Technology in Clinical Pathology Biochemistry and Pharmacology. Raven
Press, 109-117 (1989).
J-92
Govindjee,
M. vandeVen, C. Preston, M. Seibert and E. Gratton. Recombinational light
emission from photosystem II reaction centers. 8th Int'l Conf. on
Photosynthesis, Stockholm, Sweden (1989).
J-93
Feddersen,
B. M., D. W. Piston and E. Gratton. Digital parallel acquisition in frequency domain
fluorimetry.
Rev. Sci. Inst. 60(9), 2929-2936
(1989).
J-94
Piston,
D. W., G. Marriott, T. Radivoyevich, R. M. Clegg, T. M. Jovin and E. Gratton. Wide-band acousto-optic light modulator for frequency
domain fluorometry and phosphorimetry. Rev.
Sci. Inst. 60(8), 2596- 2600 (1989).
J-95
Bismuto,
E., G. Irace and E. Gratton. Multiple conformational states in myoglobin revealed
by frequency domain fluorometry.
Biochemistry 28, 1508-1512 (1989).
J-96
Piston,
D. W., T. Bilash and E. Gratton. Compartmental analysis approach to fluorescence
anisotropy: Perylene in viscous solvents.
J. Phys. Chem. 93, 3963-3967 (1989).
J-97
Gratton,
E., W. W. Mantulin, M. J. vandeVen, J. B. Fishkin, M. B. Maris and B. Chance. The possibility of a near-infrared optical imaging
system using frequency domain methods. Proc. Third Int'l Conf. for Peace
through Mind/Brain Science, pp. 183-189, Hamamatsu City, Japan (1990).
J-98
Rosato, N., E. Gratton, G. Mei and A.
Finazzi-Agrò. Fluorescence lifetime distributions in human
superoxide dismutase: Effect of temperature and denaturation. Biophys.
J. 58, 817-822 (1990).
J-99
Pin,
S., C. A. Royer, E. Gratton, B. Alpert and G. Weber. Subunit interactions in hemoglobin probed by
fluorescence and high-pressure techniques. Biochemistry
29, 9194-9202 (1990).
J-100
Barcellona, M. L., G. Cardiel and E.
Gratton. Time-resolved fluorescence of DAPI in solution and
bound to polydeoxynucleotides.
Biochem. Biophys. Res. Commun. 170(1),
270-280 (1990).
J-101
Gratton,
E., B. Feddersen and M. vandeVen. Parallel acquisition of fluorescence decay using array
detectors.
In: Proc. SPIE 1204, Time-Resolved
Laser Spectroscopy in Biochemistry II. J. R. Lakowicz, ed. 21-25 (1990).
J-102
Barbieri, B. F., F. de Piccoli, M.
Vandeven, and E. Gratton. What determines the uncertainty of phase and
modulation measurements in frequency-domain fluorometry? In:
Proc. SPIE 1204, Time-Resolved Laser Spectroscopy in Biochemistry II. J.
R. Lakowicz, ed. 158-170 (1990).
J-103
Vander
Meulen, D. L., D. G. Nealon, E. Gratton and D. M. Jameson. Excitation wave-length dependent fluorescence
anisotropy of Eosin- Myosin adducts: Evidence for anisotropic rotations. Biophys.
Chem. 36, 177-184 (1990).
J-104
Parasassi, T., G. De Stasio, A. d'Ubaldo
and E. Gratton. Phase fluctuation in phospholipid membranes revealed
by Laurdan fluorescence.
Biophys. J. 57, 1179-1186 (1990).
J-105
Rosato, N., G. Mei, E. Gratton, J. V.
Bannister, W. H. Bannister and A. Finazzi-Agrò. A time-resolved fluorescence study of human
copper-zinc superoxide dismutase.
Biophys. Chem. 36, 41-46 (1990).
J-106
Parasassi, T., G. De Stasio, A.
Miccheli, F. Bruno, F. Conti and E. Gratton. Abscisic acid induced microheterogeneity in phospholipid
vesicles. A fluorescence study.
Biophys. Chem. 35, 65-73 (1990).
J-107
Barcellona, M. L. and E. Gratton. The fluorescence properties of a DNA probe:
4'-6-diamidino-2phenylindole (DAPI). E.
Biophys. J. 17, 315-323 (1990).
J-108
Govindjee,
M. vandeVen, C. Preston, M. Seibert and E. Gratton. Chlorophyll a fluorescence lifetime distribution
functions in open and closed photosystem II reaction center preparations;
analysis by multifrequency phase fluorometry. Biochim.
Biophys. Acta 173-179 (1990).
J-109
Ferreira,
S. and E. Gratton. Hydration and
protein substates: fluorescence of proteins in reverse micelles, J.
Mol. Liq. Special Issue in Honor of G. Careri, 253-272 (1990).
J-110
Parasassi, T., G. De Stasio, G.
Ravagnan, R. M. Rusch and E. Gratton. Quantitation of
lipid phases in phospholipid vesicles by the generalized polarization of
Laurdan fluorescence.
Biophysical J., 60, 179-189 (1991).
J-111
Reinhart,
G., P. Marzola, D. M. Jameson and E. Gratton. A method for on-line background subtraction in frequency
domain fluorometry.
J. of Fluorescence 1(3) 153-162
(1991).
J-112
Di Iorio, E. E., U. R. Hiltpold, D.
Filipovic, K. H. Winterhalter, E. Gratton, E. Vitrano, A. Cupane, M.
Leone and L. Cordone. Protein dynamics:
comparative investigation on heme-proteins with different physiological roles. Biophys.
J., 59, 742-754 (1991).
J-113
Chance,
B., J. S. Leigh and E. Gratton. New Image. Nature,
349 (6311), 660 (1991).
J-114
Fishkin,
J., E. Gratton, M. J. vandeVen and W. W. Mantulin. Diffusion of intensity modulated near-infrared light
in turbid media.
In Proc. SPIE 1431, Time- Resolved
Spectroscopy and Imaging of Tissues. B. Chance and A. Katzer, eds., 122-135
(1991).
J-115
Fishkin,
J. B., B. A. Feddersen and E. Gratton. Experimental study of the diffraction of photon density
waves by an absorbing edge in highly scattering media. Proc. IEEE MTT-S International
Microwave Symp., Boston, MA. (1991).
J-116
Marzola, P. and E. Gratton. Hydration
and protein dynamics: Frequency
domain fluorescence spectroscopy on proteins in reverse micelles. J.
Phys. Chem. 95, 9488-9495 (1991).
J-117
Barcellona, M. L. and E. Gratton. A molecular approach to 4'-6-diamidine-2-phenylindole
(DAPI) photophysical behavior at different pH values. Biophys.
Chem. 40, 223-229 (1991).
J-118
Wang,
S., J. M. Beechem, E. Gratton and M. Glaser. Orientational distribution of 1,6-diphenyl-1,3,5hexatriene
in phospholipid vesicles as determined by Global analysis of frequency domain
fluorimetry data.
Biochemistry 30 (22), 5565-5572
(1991).
J-119
Parasassi, T., G. De Stasio, R. M. Rusch
and E. Gratton. A photophysical model for 1,6-Diphenyl1,3,5-Hexatriene
fluorescence decay in solvents and in phospholipid vesicles. Biophys.
J. 59(2), 466475 (1991).
J-120
Axelsen,
P. H., E. Gratton and F. G. Prendergast. Experimentally verifying molecular dynamics simulations
through fluorescence anisotropy measurements. Biochemistry
30, 1173-1179 (1991).
J-121
Parasassi,
T. and E. Gratton. Packing of
phospholipid vesicles studied by oxygen quenching of Laurdan fluorescence. J.
Fluorescence, 2 (3), 167-174 (1992).
J-122
Parasassi, T., G. Ravagnan, O. Sapora
and E. Gratton. Membrane oxidative damage induced by ionizing
radiation detected by diphenylhexatriene fluorescence lifetime distributions. Int.
J. Rad. Biol. 61(6), 791-796 (1992).
J-123
Mei, G., N. Rosato, N. Silva, R. Rusch,
E. Gratton, I. Savini and A. Finazzi-Agrò. Denaturation of
human Cu/Zn superoxide dismutase by guanidine hydrochloride: A dynamic
fluorescence study.
Biochem. J. 31(32), 7224-7230 (1992).
J-124
Gratton,
E. Frequency domain fluorescence lifetime measurements using synchrotron
radiation. In Synchrotron
Radiation and Dynamic Phenomena (A. Beswick, Ed.) Conf. Proc. 258,
Particles and Fields Series 49, 453-464 (1992).
J-125
Gratton, E., N. Silva, G. Mei, N.
Rosato, I. Savini and A. Finazzi-Agró. Fluorescence
lifetime distribution of folded and unfolded proteins. Int'l
J. of Quantum Chem. 2, 1479-1489 (1992).
J-126
Bucci,
E., Z. Gryczynski, E. Gratton and T. Tenenholz. Heme- tryptophan relationships in hemoglobin explored
by frequency-domain time- resolved fluorescence at 10 GHz resolution. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 784791 (1992).
J-127
Clegg,
R. M., B. Feddersen, E. Gratton and T. M. Jovin. Time resolved imaging fluorescence microscopy. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 448-460 (1992).
J-128
Berland,
K., E. Gratton and M. vandeVen. A laser heterodyning detector for frequency-domain
ultrafast spectroscopy. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 370-378 (1992).
J-129
Van
Der Meer, B. W., M. A. Raymer, S. L. Wagoner, R. L. Hackney, J. M. Beechem,
& E. Gratton. Models for fluorescence
energy transfer between moving donors and acceptors. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 220-229 (1992).
J-130
French,
T., E. Gratton and J. Maier. Frequency domain imaging of thick tissues using a CCD. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 254261 (1992).
J-131
vandeVen, M., B. Barbieri, E. Gratton and J.
Maier. Analysis of
noise sources in frequency domain fluorometry. In
Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III.
J. R. Lakowicz, ed., 332-341 (1992).
J-132
Fishkin,
J. and E. Gratton. Diffraction of
intensity modulated light in strongly scattering media in the presence of a
"semi-infinite" absorbing or reflecting plane bounded by a straight
edge.
In Proc. SPIE 1640, Time-Resolved
Laser Spectroscopy in Biochemistry III. J. R. Lakowicz, ed., 362-367
(1992).
J-133
Silva, N., E. Gratton, G. Mei, N.
Rosato, R. Rusch and A. Finazzi-Agrò. Molten globule
monomers in human superoxide dismutase. Biophys.
Chem. 48, 171-182 (1993).
J-134
Bismuto,
E., E. Gratton, I. Sirangelo, and G. Irace. Structure and dynamics of the acidic compact state of
apomyoglobin by frequency-domain fluorometry. Eur.
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J-135
Mantulin,
W. W., J. B. Fishkin, P. T. C. So, E. Gratton and J. S. Maier. Quantitative diffusive wave spectroscopy in tissues. In
Proc. SPIE 1888, Photon Migration and Imagining in Random Media and Tissues.
B. Chance and R. R. Alfano, eds., 420-427 (1993).
J-136
Maier,
J. S. and E. Gratton. Frequency-domain
methods in optical tomography: detection of localized absorbers and a
backscattering reconstruction scheme. Photon Migration and Imagining in
Random Media and Tissues (B. Chance and R. R. Alfano, Ed.), SPIE Proc.
1888, 440-451 (1993).
J-137
Govindjee,
M. vandeVen, J. Cao, C. Royer and E. Gratton. Multifrequency cross-correlation phase fluorometry of
chlorophyll a fluorescence in thylakoid and PSII-enriched membranes. Photochem.
and Photobiol. 58 (3), 438-445 (1993).
J-138
Mantulin,
W. W., T. French and E. Gratton. Optical imaging in the frequency domain. In:
Proc. SPIE 1892, Medical Laser and Systems II. D. M. Harris and C. KM.
Penny, eds., 158-166 (1993).
J-139
Zolese, G., R. Staffolani, L. Mazzanti
and E. Gratton. Effect of divalent cations on Na+, K+ -ATPase obtained
from human placenta.
Fed. of European
Biochem. Soc. 323 (1,2) 11-14 (1993).
J-140
Van
Der Meer, B. W., M. A. Raymer, S. L. Wagoner, R. L. Hackney, J. M. Beechem, and
E. Gratton. Designing
matrix models for fluorescence energy transfer between moving donors and
acceptors.
Biophys. J. 64(4), 1243-1263 (1993).
J-141
Fiorini, R., G. Curatola, A. Kantar, P.
L. Giorgi and E. Gratton. Use of Laurdan fluorescence in studying plasma
membrane organization of polymorphonuclear leukocytes during the respiratory
burst.
Photochem. and
Photobiol. 57 (3), 438-441 (1993).
J-142
Levi,
M., P. V. Wilson, O. J. Cooper and E. Gratton. Lipid phases in renal brush border membranes revealed
by Laurdan fluorescence.
Photochem. and
Photobiol. 57(3), 420-425 (1993).
J-143
Parasassi,
T., G. Ravagnan, R. M. Rusch and E. Gratton. Modulation and dynamics of phase properties in phospholipid
mixtures detected by Laurdan fluorescence. Photochem.
and Photobiol. 57(3), 403-410 (1993).
J-144
Gratton,
E., W. W. Mantulin, M. J. vandeVen, J. B. Fishkin, M. B. Maris and B. Chance. A novel approach to laser tomography. Bioimaging
40-46 (1993).
J-145
Fishkin,
J. and E. Gratton. Propagation of
photon density waves in strongly scattering media containing an absorbing
"semi-infinite" plane bounded by a straight edge. J.
of the Optical Soc. of America A. 10(1), 127-140 (1993).
J-146
Maris,
M., E. Gratton, J. Maier, W. Mantulin and B. Chance. Functional near-infrared imaging of deoxygenated
hemoglobin during exercise of the finger extensor muscles using the
frequency-domain technique.
Bioimaging 2, 174-183 (1994).
J-147
Berland,
K. M., So, P. T. C. and E. Gratton. Two-photon fluorescence correlation spectroscopy:
method and application to the intracellular environment. Biophys.
J. 68, 694-701 (1995).
J-148
Silva,
N., E. Gratton and G. Mei. Proteins
fluorescence and conformational substates: The dynamics of human superoxide
dismutase.
Comments on Cell. and
Mol. Biophys. 8 (4), 217-242 (1994).
J-149
Maier, J. S., S. A. Walker, S. Fantini,
M. A. Franceschini and E. Gratton. Possible
correlation between blood glucose concentration and reduced scattering
coefficient of tissues in the near-infrared. Optics
Letters 19 (24), 2062-2064 (1994).
J-150
Parasassi, T., M. Di Stefano, M. Loiero,
G. Ravagnan and E. Gratton. Cholesterol modifies water concentration and dynamics
in phospholipid bilayers. A fluorescence study using Laurdan probe. Biophys.
J. 66, 763-766 (1994).
J-151
Parasassi, T., M. Di Stefano, M. Loiero,
G. Ravagnan and E. Gratton. Influence of cholesterol on phospholipid bilayers
phase domains as detected by Laurdan fluorescence. Biophys.
J. 66, 120-132 (1994).
J-152
Parasassi, T., A. M. Giusti, E. Gratton,
E. Monaco, M. Raimondi, G. Ravagnan and O. Sapporo. Evidence for an
increase in water concentration in bilayers after oxidative damage of
phospholipids induced by ionizing radiation. Int.
J. Radiat. Biol. 65, 329-334 (1994).
J-153
Ferreira,
S. T. and E. Gratton. Anisotropic
rotational diffusion of the adenine moiety in 1,N6ethenoadenosine
triphosphate (-ATP) in viscous solvents investigated by time-resolved
fluorescence spectroscopy.
J. of the Amer. Chem. Soc. 116 (13),
5791-5795 (1994).
J-154
Fantini, S., M. A. Franceschini, J. B.
Fishkin, B. Barbieri and E. Gratton. Quantitative
determination of the absorption spectra of chromophores in strongly scattering
media: a light-emitting-diode based technique. Appl.
Opt. 33 (22), 5204-5213 (1994).
J-155
Gratton, E., S. Fantini, M. A.
Franceschini, J. B. Fishkin and J. Maier. Near-infrared
optical spectroscopy of tissues using an LED frequency domain spectrometer. Proc.
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J-156
So,
P., T. French and E. Gratton. A frequency
domain time-resolved microscope using a fast-scan CCD camera. In
Proc. SPIE 2137, Time resolved Laser Spectroscopy in Biochemistry IV, J.
R. Lakowicz, ed., 83-92 (1994).
J-157
Gryczynski, Z. C.Fronticelli, E.
Gratton, J. Lubkowski, E. Bucci. Effect of disordered hemes and dimerization in
isolated a-subunits of hemoglobin detected by time-resolved fluorescence
spectroscopy in the picosecond range.
In Proc. SPIE 2137, Time resolved
Laser Spectroscopy in Biochemistry IV, J. R. Lakowicz, ed., 129-134 (1994).
J-158
Fantini, S., M. A. Franceschini and E.
Gratton. Semi-infinite
geometry boundary problem for light migration in highly scattering media: a
frequency-domain study in the diffusion approximation. J.
Optical Soc. of Amer.11(10),
2128-2138 (1994).
J-159
Fantini, S., M. A. Franceschini, J. B.
Fishkin and E. Gratton. Absolute
measurement of absorption and scattering coefficients spectra of a multiply
scattering medium.
In: Proc. SPIE 2131, Biomedical
Fiber Optic Instrumentation, A. Katzir, ed., 356-364 (1994).
J-160
Fantini, S., M. A. Franceschini and E.
Gratton. LED based quantitative measurement of
absorption and scattering coefficient spectra of a strongly scattering medium. In Proc. SPIE 2131, Biomedical Fiber
Optic Instrumentation. A. Katzir, ed., 356-364 (1994).
J-161
Franceschini, M. A., S. Fantini and E.
Gratton. LED's in
frequency-domain spectroscopy of tissues. In
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Cancer and Other Diseases. R. R. Alfano, ed., 300-306 (1994).
J-162
Mantulin,
W. W. and E. Gratton. Spectroscopic
innovations at the Laboratory for Fluorescence Dynamics. In:
Proc. SPIE 2100, Cell and Biotissue Optics: Applications in Laser
Diagnostics and Therapy. V. V. Tuchin, ed., 6-18 (1994).
J-163
Fantini, S., M. A. Franceschini, J. B.
Fishkin, W. W. Mantulin and E. Gratton. The absorption spectra of a chromophore in highly
scattering media.
In: Proc. SPIE 2100, Cell and
Biotissue Optics: Applications in Laser Diagnostics and Therapy. V. V.
Tuchin, ed., 114-123 (1994).
J-164
Brunet,
J. E., V. Vargas, E. Gratton and D. Jameson. Hydrodynamics of horseradish peroxidase revealed by
global analysis of multiple fluorescence probes. Biophys.
J. 66, 446-453 (1994).
J-165
Ferreira, S. T., L. Stella and E.
Gratton. Conformational
dynamics of bovine Cu, Zu superoxide dismutase revealed by time-resolved
fluorescence spectroscopy of the single tyrosine residue. Biophys.
J. 66, (4), 1185-1196 (1994).
J-166
Gratton, G., J. S. Maier, M. Fabiani, W.
W. Mantulin and E. Gratton. Feasibility of intracranial
near-infrared optical scanning.
Psychophysiology 31, 211-215 (1994).
J-167
Gratton,
E. and J. Maier. Frequency-domain measurements of photon migration in highly
scattering media. In Proc. SPIE
Medical Optical Tomography: Functional Imaging and Monitoring. G. Müller, B. Chance, R. Alfano, S. Arridge,
J. Beuthan, E. Gratton, M. Kaschke, B. Masters, S. Svanberg and P. van der Zee,
eds., 534-544 (1994).
J-168
Parasassi, T., M. Loiero, M. Raimondi,
G. Ravagnan and E. Gratton. Absence of lipid gel-phase domains in seven mammalian
cell lines and in four primary cell types. Biochim.
Biophys. Acta 1153, 143-154 (1994).
J-169
Bernsdorff,
C., R. Winter, T. L. Hazlett, and E. Gratton. Influence of Cholesterol and BSitosterol on the Dynamic
Behaviour of DPPC as Detected by TMA-DPH and PyrPc Fluorescence: A Fluorescence
Lifetime Distribution and Time-Resolved Anisotropy Study, Ber. Bunsenges. Phys. Chem. 99, 1479-1488 (1995).
J-170
So,
P. T. C., T. French, W. M. Yu, K. M. Berland, C. Y. Dong, and E. Gratton. Time-resolved fluorescence microscopy using two photon excitation. Bioimaging
3, 49-63 (1995).
J-171
Giusti, A. M., E. Gratton, T. Parasassi,
M. Raimondi and G. Ravagnan. Cholesterol effects on membrane structure and dynamics
as detected by Laurdan fluorescence. Biochimica
in Italia 3 64-72 (1995).
J-172
Parasassi, T., A. M. Giusti, M.
Raimondi, G. Ravagnan, O. Sapora and E. Gratton. Cholesterol protects the phospholipid bilayer from
oxidative damage.
Free Radical Biol. and Med. 19 (4),
511516 (1995).
J-173
Gratton, G., M. Fabiani, D. Friedman, M.
A. Franceschini, S. Fantini, P. M. Corballis, and E. Gratton. Rapid changes of optical parameters in the human brain
during a tapping task.
J. Cognitive Neuroscience 7 (4),
446-456 (1995).
J-174
Gratton,
E. and J. B. Fishkin. Optical spectroscopy
of tissue-like phantoms using photon density waves. Comments
on Cell. and Mol. Biophys. 8(6), 309-359 (1995).
J-175
Franceschini,
M. A., S. Fantini, S. A. Walker, J. S. Maier, W. W. Mantulin and E. Gratton. Multichannel optical instrument for near-infrared
imaging of tissue. In
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Tissue and Model Media: Theory, Human Studies, and Instrumentation. B. Chance,
R. R. Alfano, eds., 264-273 (1995).
J-176
J. S. Maier, B. Barbieri, A. Chervu, I.
Chervu, S. Fantini, M. A. Franceschini, M. Levi W. W. Mantulin, A. Rosenberg,
S. A. Walker and E. Gratton. In vivo study of human tissues with a portable
near-infrareD tissue spectrometer.
In Proc. SPIE 2387, Advances in
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Alfano, ed., 240-248 (1995).
J-177
Ferrari, M., R. A. De Blasi, S. Fantini,
M. A. Franceschini, B. Barbieri, V. Quaresima and E. Gratton. Cerebral and muscle oxygen saturation measurement by a
frequency-domain near-infrared spectroscopic technique.
In Proc. SPIE 2389, Advances in Laser
and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R.
Alfano, ed., 868-874 (1995).
J-178
Fantini, S., M. A. Franceschini, S. A.
Walker, J. S. Maier and E. Gratton. Photon path distributions in turbid media:
applications for imaging.
In Proc. SPIE 2389, Advances in
Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R.
Alfano, ed., 340-349 (1995).
J-179
Walker,
S. A., A. E. Cerussi and E. Gratton. Back-projection image reconstruction using photon
density waves in tissues.
In Proc. SPIE 2389, Advances in
Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R.
Alfano, ed., 350-357 (1995).
J-180
Gratton,
E. and T. Parasassi. Fluorescence
lifetime distributions in membrane systems. J.
of Fluorescence 5 (1), 51-57 (1995).
J-181
Parasassi, T., A. M. Giusti, M. Raimondi
and E. Gratton. Abrupt
modification of phospholipid bilayer properties at critical cholesterol
concentrations,
Biophys. J. 68 (5), 1895-1902 (1995).
J-182
Maier, J. S., S. Fantini, M. A.
Franceschini-Fantini, W. W. Mantulin, S. A. Walker and E. Gratton. Application
of a portable near-infrared spectrometer in the study of several human tissues.
SPIE Proc. 2387 240-248 (1995).
J-183
Mantulin, W. W., S. Fantini, M. A.
Franceschini-Fantini, S. A. Walker, J. S. Maier, and E. Gratton. Tissue optical parameter map generated with frequency
domain spectroscopy. In:
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eds., 323-330 (1995).
J-184
Fantini, S., M. A. Franceschini, J. S.
Maier, S. A. Walker and E. Gratton. Frequency-domain multisource optical spectrometer and
oximeter,
In: Proc. SPIE 2326 Photon
Transport in Highly Scattering Tissue; Biomedical Optics Europe'94, Lille,
France. S. Avrillier, B.
Chance, G. J. Mueller, A. V. P., V. V. Tuchin, eds.,
108-115 (1995).
J-185
Carrero,
J., D. M. Jameson and E. Gratton. Oxygen penetration and diffusion into myoglobin
revealed by quenching of Zincprotoporphyrin IX fluorescence. Biophys.
Chem. 54 143-154 (1995).
J-186
Fishkin, J. B., P. T. C. So, A. E.
Cerussi, S. Fantini, M. A. Franceschini and E. Gratton. Frequency-domain method for determining spectral
properties in multiple scattering media: methemoglobin absorption spectrum in a
tissue-like phantom.
Applied Optics 34 (7), 1143-1155
(1995).
J-187
Fantini, S., M. A. Franceschini, J. S.
Maier, S. A. Walker, B. Barbieri and E. Gratton. Frequency-domain multichannel optical detector for
non-invasive tissue spectroscopy and oximetry. Opt.
Eng. 34 (1), 32-42 (1995).
J-188
De Blasi, R. A., S. Fantini, M. A.
Franceschini, M. Ferrari and E. Gratton. Cerebral and muscle oxygen saturation measurement by a
novel frequency-domain near-infrared spectrometer. Medical
& Biological Engineering & Computing 33, 228-230 (1995).
J-189
Parasassi,
T. and E. Gratton. Membrane lipid
domains and dynamics as detected by Laurdan fluorescence. J.
of Fluorescence. 5 (1), 59-69 (1995).
J-190
Dong,
C. Y., P. T. C. So, T. French, and E. Gratton. Fluorescence lifetime imaging by asynchronous
pump-probe microscopy.
Biophys. J. 69, 2234-2242 (1995).
J-191
Gratton,
E., C. Y. Dong, P. T. C. So. Fluorescence
Lifetime Microscopy: A Stimulated-emission Approach. In:
Proc. SPIE 2678, Optical Diagnostics of Living Cells and Biofluids. D.
L. Farkas, R. C. Leif, A. V. Priezzhev, T. Asakura, B. J. Tromberg, eds.,
98-109 (1996).
J-192
Walker,
S., S. Fantini and E. Gratton. Back-projection reconstructions of cylindrical
inhomogeneities from frequency domain optical measurements in turbid media. OSA
Trends in Optics and Photonics on Advances in Optical Imaging and Photon
Migration 2, R. R. Alfano and J. G. Fujimoto, eds., 137141 (1996).
J-193
Maier, J. S., A. Cerussi, S. Fantini, M.
A. Franceschini and E. Gratton. Quantitative fluorescence in tissue-like media. OSA Trends in Optics and
Photonics on Biomedical Optical Spectroscopy and Diagnostics 3, E.
Sevick-Muraca and D. Benaron, eds., 206-209 (1996).
J-194
Cerussi, A., J. Maier, S. Fantini, M. A.
Franceschini and E. Gratton. The frequency-domain multi-distance method in the
presence of curved boundaries.
OSA Trends in Optics and Photonics on Biomedical Optical Spectroscopy and
Diagnostics 3, E. Sevick-Muraca and D. Benaron, eds., 92-97 (1996).
J-195
Franceschini, M. A., S. Fantini, A.
Cerussi, B. Barbieri, B. Chance and E. Gratton. The effect of water in the quantitation of hemoglobin
concentration in a tissue-like phantom by near-infrared spectroscopy. OSA Trends in Optics and
Photonics 3, E. Sevick-Muraca and D. Benaron, eds., 126130 (1996).
J-196
Mei, G., A. Di Venere, G. Gilardi, N.
Rosato, R. McKay, E. Gratton and A. Finazzi-Agró. Two
classes of tryptophans in ascorbate oxidase revealed by time resolved
fluorescence. OSA Trends in Optics and Photonics on Advances in Optical
Imaging and Photon Migration 2, R. R. Alfano and J. G. Fujimoto, Eds.
(1996).
J-197
Bismuto,
E., G. Irace, E. Sirangelo and E. Gratton. Pressure-induced perturbation of ANSapomyoglobin
complex: Frequency domain fluorescence studies on native and acidic compact
states.
Protein Science 5(1) 121-126 (1996).
J-198
Berland,
K. M., P. T. C. So, Y. Chen, W. W. Mantulin and E. Gratton. Scanning two-photon fluctuation correlation
spectroscopy: Particle counting measurements for detection of molecular
aggregation.
Biophys. J. 71, 410-420 (1996).
J-199
Gratton, E., S. Fantini, M. A.
Franceschini, S. Walker, and J. Maier. Spectroscopy and tomography of tissues in the
frequency-domain.
October 14-18, 1995, Proc. NATO ARW Workshop on Analytical Use of Fluorescent
Probes in Oncology, Miami FL (1996).
J-200
Parasassi,
T. and E. Gratton. Comments on DPH
fluorescence decrease at critical cholesterol concentration in phospholipid
membranes.
Biophys. J. March (1996).
J-201
Barcellona, M. L. and E. Gratton. Torsional dynamics and orientation of DNA-DAPI
complexes.
Biochemistry 35, 321-333 (1996).
J-202
Barcellona M. L. and E. Gratton. Fluorescence anisotropy of DNA/DAPI complex: Torsional
dynamics and geometry of the complex. Biophys.
J. 70 (5), 2341-2351 (1996).
J-203
Yu,
W., P. T. C. So, T. French, and E. Gratton. Fluorescence generalized polarization of cell
membranes-a two photon scanning microscopy approach. Biophys.
J. 70, 626-636 (1996).
J-204
Gratton, E., G. Gratton, M. Fabiani and
P. M. Corballis. Detection of brain activity using
time-resolved interfered techniques. Proc. 5th Conference on Mind-Brain
Science Hamamatsu City, Japan. (1996).
J-205
Fishkin,
J. B., S. Fantini, M. J. van de Ven, and E. Gratton. GigaHertz photon density waves in a turbid medium:
Theory and experiments.
Phys. Rev. E. 53, 2307-2319 (1996).
J-206
Gratton,
E., W. W. Mantulin, G. Weber, C. A. Royer, R. Reininger and R. W. C. Hansen. Fluorescence dynamics of biological systems using
synchrotron radiation.
Rev. Sci. Instrum. 66 (9), 1-7
(1996).
J-207
Fantini,
S., M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T.
Moesta, P. M. Schlag, and M. Kaschke. Frequency-domain optical mammography: Edge effect
corrections. Med. Phys. 23
(1), 149-157 (1996).
J-208
Berberan-Santos,
M. N., J. Canceill, E. Gratton, L. Jullien, J.-M. Lehn, P. So, J. Sutin and B.
Valeur. Multichromophoric
cyclodextrins. 3. Investigation of dynamics of energy hopping by
frequency-domain fluorometry.
J. Phys. Chem. 100 15-20 (1996).
J-209
Koenig,
K., P. T. C. So, W. W. Mantulin, and E. Gratton. Cell damage in two-photon microscopes In:
Proc. SPIE 2926, Optical Biopsies and Microscopic Techniques. I. J.
Bigio, W. S. Grundfest, H. Schneckenburger, K. Svanberg, P. M. Viallet, eds.
172-176 (1996).
J-210
Koenig,
K., P. T. C. So, W. W. Mantulin, B. J. Tromberg and E. Gratton. Two-photon excited lifetime imaging of
autofluorescence in cells during UVA and NIR photostress. J.
Microscopy 183, 197-204 (1996).
J-211
Bismuto, E., I. Sirangelo, G. Erace, and
E. Gratton. Pressure-induced
perturbation of apomyoglobin structure: Fluorescence studies on native and
acidic compact forms. Biochemistry 35,
1173-1178, (1996).
J-212
Koenig, K., P. T. C. So, W. W. Mantulin,
E. Gratton, T. Krasieva, M. W. Berns and B. J. Tromberg. Two-photon excited cellular autofluorescence induced
by cw and femtosecond NIR microradiation. Proc. SPIE, Int. Soc. Opt. Eng.,
2628 , 12-19 (1996).
J-213
Zolese, G., E. Giambanco, G. Curatola, R.
Staffolani, E. Gratton, and R. Donato. Time-resolved fluorescence of S-100a protein: Effect
of Ca2+, Mg2+ and unilamellar vesicles of egg phosphatidylcholine. Cell
Calcium 20(6), 465-474 (1996).
J-214
Fantini, S., M. A. Franceschini and E.
Gratton. Effective
source term in the diffusion equation for photon transport in turbid media. Appl.
Opt. 36(1) , 156-163 (1996).
J-215
Maier,
J., S. Walker and E. Gratton. Frequency-domain optical spectroscopy and imaging of
tissues.
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J-216
Fantini, S., M. A. Franceschini, G.
Gaida, H. Jess, H. Erdl, W. W. Mantulin, E. Gratton, K. M. Moesta, P. M. Schlag
and M. Kaschke. Contrast
enhancement by edge effect corrections in frequency-domain optical mammography. OSA Trends in Optics and
Photonics on Advances in Optical Imaging and Photon Migration 2, R. R.
Alfano and J. G. Fujimoto, eds., 160-163 (1996).
J-217
Jess, H., H. Erdl, K. T. Moesta, S.
Fantini, M. A. Franceschini, E. Gratton, and M. Kaschke. Intensity
modulated breast imaging: Technology and clinical pilot study results. OSA
Trends in Optics and Photonics on Advances in Optical Imaging and Photon
Migration 2, R. R. Alfano and J. G. Fujimoto, eds., 126-129 (1996).
J-218
Gratton,
G., M. Fabiani, P. Corballis, D. C. Hood, M. Goodman, J. Hirsch, K. Kim, D.
Friedman and E. Gratton. Fast and localized event-related optical signals
(EROS) in the human occipital cortex: Comparisons with the visual evoked
potential and fMRI.
Neuroimage 6, 168-180 (1997).
J-219
Fantini,
S., M. A. Franceschini, and E. Gratton, Effective source term in the diffusion equation for
photon transport in turbid media,
Appl. Opt. 36, 156-163 (1997).
J-220
Dong,
C. Y., P. T. C. So, C. Buehler and E. Gratton. Spatial resolution in scanning pump-probe fluorescence
microscopy. Optik,
106(1) 7-14 (1997).
J-221
Gratton, E., S. Fantini, M. A.
Franceschini, G. Gratton and M. Fabiani. Measurements of scattering and absorption changes in
muscle and brain.
Phil. Trans. R. Soc. London. B 352 , 727-735 (1997).
J-222
Franceschini, M. A., S. Fantini, A.
Cerussi, B. Barbieri, B. Chance and E. Gratton. Quantitative spectroscopic determination of hemoglobin
concentration and saturation in turbid medium: Analysis of the effect of water
absorption.
J. of Biomedical Optics 2(2), 147-153
(1997).
J-223
Franceschini,
M. A., K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin,
M. Seeber, P. M. Schlag, and M. Kaschke. Frequency-domain techniques enhances optical
mammography: Initial clinical results. Proc.
Natl. Acad. Sci. USA, 94, 6468-6473 (1997).
J-224
Masters,
B. R., P. T. C. So, and E. Gratton. Multi-photon excitation fluorescence and spectroscopy
of in vivo human skin.
Biophys. J. 72, 2405-2412 (1997).
J-225
Barshtein.
G., L. Bergelson, A. Dagan,
E. Gratton and S. Yedgar, S. Membrane lipid order of human red cells is altered by
physiological levels of hydrostatic pressure. Amer.
J. Physiol., Heart and Circulatory Physiology, 272, H538-H543 (1997).
J-226
Koenig,
K., P. T. C. So, W. W. Mantulin, and E. Gratton, Cell Damage in Two-Photon
Femtosecond Microscopes, Applied Optics 22,
135 (1997).
J-227
Parasassi,
T., E. Gratton, W. Yu, P. Wilson, and M. Levi. Two-photon fluorescence microscopy of laurdan
gp-domains in model and natural membranes. Biophys.
J. 72 (5), 2413-2429 (1997).
J-228
Cerussi, A., J. S. Maier, S. Fantini, M.
A. Franceschini, W. W. Mantulin and E. Gratton. Experimental verification of a theory for the
time-resolved fluorescence spectroscopy of thick tissues. Diffusing Photons in
Turbid Media,
Appl. Opt. 36(1) ,
116-124 (1997).
J-229
S.
Fantini, K. T. Moesta, M. A. Franceschini, H. Jess, H. Erdl, E. Gratton, P. M.
Schlag, and M. Kaschke, "Instrumentation
and Clinical Applications in Frequency-Domain optical Mammography," Proc.
19th Int. Conf.-IEEE/EMBS on Photon Migration Tomography (MS21), A. H.
Hielscher and L. Wang, chairs, pp. 2741-2744 (1997).
J-230
French,
T., P. T. C. So, D. J. Weaver, Jr., T. Coelho-Sampaio, E. Gratton, E. W. Voss,
Jr., and J. Carrero. Macrophage-mediated processing of an exogenous
fluorescent antigenic probe. I. Use of processing probe with two photon
fluorescence microscopy with time resolved and intensity imaging. J.
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J-231
Koenig,
K., H. Liang, S. Kimel, O. Svaasand, B. J. Tromberg, T. b. Krasieva, M. W.
Berns,K. J. Halbhuber, P. T. C. So, W. W. Mantulin, and E. Gratton, Cell damage in UVA and CW/Femtosecond NIR Microscopes.
In Functional Imaging and
Optical Manipulation of Livings Cells, SPIE Proc. 2983, 37-44 (1997).
J-232
So, P. T. C., T Ragan, E. Gratton, J.
Carrero, E, Voss. Two-photon
Single Particle Tracking in 3-D. In
Functional Imaging and Optical Manipulation of Livings Cells, SPIE Proc.
2983, 45-56 (1997).
J-233
So,
P. T. C., K. H. Duggar, K. M. Berland and E. Gratton. Generating an
Intracellular Diffusion Map by Two-photon Fluorescence Correlation
Spectroscopy, In Material Science
of the Cell, Symposium Material Research Society (1997).
J-234
Walker,
S. A., S. Fantini and E. Gratton. Image reconstruction using back-projection from
frequency domain optical measurements in highly scattering media. Appl.
Opt. 36(1) ,
170-179 (1997).
J-235
Bernsdorff,
C., A. Wolf, R. Winter, and E. Gratton. Effect of hydrostatic pressure on water penetration
and rotational dynamics in phospholipid-cholesterol bilayers. Biophys.
J. 72, 1264-1277 (1997).
J-236
Cerussi, A. E., S. Fantini, J. S. Maier,
W. W. Mantulin, and E. Gratton. Chromophore detection by fluorescence spectroscopy in
tissue-like phantoms.
SPIE Proc., Optical Tomography and Spectroscopy of Tissue: Theory,
Instrumentation, Model, and Human Studies II, 2979 pp. 139-150 (1997).
J-237
Maier, J. S., A. E. Cerussi, S. Fantini,
and E. Gratton. Experimental
recovery of absorption, scattering, and fluorescence parameters in
highly-scattering media from a single measurement. SPIE Proc., Optical Tomography
and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies
II, 2979 6-13 (1997).
J-238
Walker,
S. A., S. Fantini, and E. Gratton. The effect of index of refraction mismatch on the
recovery of optical properties of cylindrical inhomogeneities in an infinite
turbid medium. SPIE
Proc., Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation,
Model, and Human Studies II, 2979 219-225 (1997).
J-239
Franceschini, M. A., D. Wallace, B.
Barbieri, S. Fantini, W. W. Mantulin, S. Pratesi, G. P. Donzelli and E.
Gratton. Optical study
of the skeletal muscle during exercise with a second generation
frequency-domain tissue oximeter.
SPIE Proc., Optical Tomography and Spectroscopy of Tissue: Theory,
Instrumentation, Model, and Human Studies II, 2979 807-814 (1997).
J-240
Fantini, S., M. A. Franceschini, and E. Gratton. Effect of spatially distributed light sources on the
frequency-domain solution to the diffusion equation. SPIE Proc., Optical Tomography and Spectroscopy of
Tissue: Theory, Instrumentation, Model, and Human Studies II, 2979 807-814
(1997).
J-241
Franceschini, M. A., S. Fantini, L. A.
Paunescu, J. S. Maier, and E. Gratton. Influence of a superficial layer in the quantitative
spectroscopic study of strongly scattering media. Appl.
Opt. 37, 7447-7458 (1998).
J-242
Masters,
B.R., P. T. So, and E. Gratton. Multiphoton Excitation Microscopy of In Vivo Human
Skin: Functional and Morphological Optical Biopsy Based on Three-Dimensional
Imaging, Lifetime Measurements and Fluorescence Spectroscopy. Annals
of the New York Academy of Sciences. 838:58-67 (1998).
J-243
Chance
B., M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg. Phase measurement of light absorption and scatter in
human tissue. Rev. of Sci. Inst. 69
(10), 3457-3481, (1998).
J-244
Di Venere, A., G. Mei, G. Gilardi, N.
Rosato, F. De Matteis, R. McKay, E. Gratton, and S. Finazzi-Agró. Resolution of heterogeneous fluorescence in
multi-tryptophan proteins: ascorbate oxidase. Eur.
J. Biochem. 257, 337-343, (1998).
J-245
Walker,
S. A., D. A. Boas, and E. Gratton. Photon density waves scattered from cylindrical
inhomogeneities: Theory and experiments. Appl.
Opt. 37(10), 1935-1944 (1998).
J-246
Krasnowska,
E., K., E. Gratton, and T. Parasassi. Prodan as a membrane surface fluorescence probe.
Partitioning between water and phospholipid phases. Biophys.
J. 74: 1984-1993 (1998).
J-247
Bagatolli,
L. A., E. Gratton and G. D. Fidelio. Water dynamics in glysophingolipid aggregates studied
by Laurdan fluorescence. Biophys. J.
75:331-341 (1998).
J-248
Parasassi,
T., E. K. Krasnowska, L. Bagatolli, and E. Gratton. Laurdan and prodan as polarity-sensitive fluorescent
membrane probes.
J. of Fluorescence 8 (4), 365-373
(1998).
J-249
Toronov, V., M. Filiaci, S. Fantini, and
E. Gratton. Photon-density
wave correlation spectroscopy detects large-scale fluctuations in turbid media. Phys.
Rev. E. 58, 2288-2297 (1998)
J-250
Fantini,
S., S. A. Walker, M. A. Franceschini, K. T. Moesta, P. M. Schlag, M. Kaschke,
and E. Gratton. Assessment of
the size, position, and optical properties of breast tumors in vivo by noninvasive
optical methods,
Appl. Opt. 37, 1982-1989 (1998).
J-251
So,
P. T. C., K. Koenig, K. M. Berland, C. Y Dong, T. French, C. Buehler, T. Ragan,
and E. Gratton. New
Time-resolved Techniques in Two-photon Microscopy, Cell.
Mol. Biol. 44, 771-773 (1998).
J-252
Masters,
B. R., P. So, E. Gratton, Optical Biopsy of In vivo human skin: Multi-photon
excitation microscopy, Lasers in Medical Science
13, 197-204 (1998).
J-253
Kim,
K. H., P. T. C. So, I. E. Kochevar, B. R. Masters, and E. Gratton, Two-photon fluorescence and confocal reflected light
imaging of thick tissue structures, SPIE Proc. 3260, Eds., D. L.
Farkas, R. C. Leif, and B. J. Tromberg, 46-57 (1998).
J-254
Franceschini, M. A., S. Fantini, R.
Palumbo, L. Pasqualini, G. Vaudo, E. Franceschini, E. Gratton, B. Palumbo, S.
Innocente and E. Mannarino. Quantitative near-infrared spectroscopy on patients
with peripheral vascular disease.
In: Proc. SPIE 3194 (BIOS
Europe '97, San Remo, Italy, Sept. 4-8) 112-115 (1998).
J-255
Quaresima, V., M. A. Franceschini, S.
Fantini, E. Gratton and M. Ferrari. Difference in leg muscles oxygenation during treadmill
exercise by a new near infrared frequency-domain oximeter. In:
Proc. SPIE 3194 (BIOS Europe '97, San Remo, Italy, Sept. 4-8) 116-120
(1998).
J-256
Toronov, V., M. Filiaci, M.
Franceschini, S. Fantini, and E. Gratton. Exploring tissue dynamics by photon-density-wave
fluctuation correlation spectroscopy, Proc. SPIE 3726,
Eds., Tuchin, Ryabukho, Zimnyakov, pp. 555-559 (1999).
J-257
Cerussi,
A. E., E. Gratton, and S. Fantini, Fluorescence lifetime spectroscopy in
multiple-scattering environments: An application to biotechnology, SPIE Proc. 3600, Eds.,
Bornhop, Contag, and Sevick, pp. 171-181, (1999)
J-258
Casavola, C., L. A. Paunescu, S.
Fantini, M. A. Franceschini, P. M. Lugara, and E. Gratton. Application of near-infrared tissue oximeter to the
diagnosis of peripheral vascular disease. Clinical
Hemorheology and Microcirculation 21, 389-393
(1999).
J-259
Nayfeh,
M., O. Akcakir, J. Theiren, Z. Yamani, N. Barry, W. Yu and E. Gratton. Highly nonlinear photoluminescence threshold in porous
silicon,
Appl. Phys. Lett. 75 4112 (1999).
J-260
Bagatolli, L. A., T. Parasassi, G.D.
Fidelio, and E. Gratton. A model for the interaction of
6-Lauroyl2-(N,N-dimethylamino)naphthalene with lipid
environments: Implications for spectral properties. Photochem.
and Photobiol. 70 (4), 557-564 (1999).
J-261
Bagatolli,
L. A. and E. Gratton. Two-photon
fluorescence microscopy observation of shape changes at the phase transition in
phospholipid's giant unilamellar vesicles. Biophys.
J. 77, 2090-2101 (1999).
J-262
Stankovic,
M. R., D. Maulik, W. Rosenfeld, P. G. Stubblefield, A. D. Kofinas, S. Drexler,
R. Nair, M. A. Franceschini, D. Hueber, E. Gratton, and S. Fantini, Real-Time Optical Imaging of Experimental Brain
Ischemia and Hemorrhage in Neonatal Piglets, J.
Perinat. Med. 27 (4) 279-286 (1999).
J-263
Fantini,
S., D. Hueber, M. A. Franceschini, E. Gratton, W. Rosenfeld, P. G.
Stubblefield, D. Maulik, and M. R. Stankovic. Noninvasive optical monitoring of the newborn piglet
brain using continuous-wave and frequency-domain spectroscopy. Physics
in Med. and Biol. 44(6), 1543-63 (1999).
J-264
Franceschini, M. A., E. Gratton, and S.
Fantini. Noninvasive
optical method of measuring tissue and arterial saturation: an application to
absolute pulse oximetry of the brain. Opt.
Lett. 24 (12), 829-831, (1999).
J-265
Chen,
Y., J. D. Müller, P. T. C. So, and E. Gratton, The Photon Counting Histogram in Fluorescence
Fluctuation Spectroscopy,
Biophys. J. 77: 553-567 (1999).
J-266
Buehler,
C., K. H. Kim, B. R. Masters, P. T. C. So, I. E. Kochevar, and E. Gratton,
Two-photon Deep Tissue Imaging, IEEE
Engineering in Medicine and Biology 18, 23-30 (1999).
J-267
Masters,
B. R., P. T. C. So, and E. Gratton, Multiphoton excitation microscopy and confocal
microscopy of human skin in vivo,
Comments on Cell. and
Mol. Biophys. 9(6), 379-405 (1999).
J-268
Masters,
B. R., P. T. C. So, K. H. Kim, C. Buehler, and E. Gratton. Multiphoton Excitation microscopy, Confocal
Microscopy, and Spectroscopy of Living Cells and Tissues; Functional Metabolic
Imaging of Human Skin In Vivo,
Methods Enzymol, 307, 513-536 (1999).
J-269
Masters,
B. R., P. T. C. So, E. Gratton, G. Gonnord, P. Corcuff, Microscopy of Human
Skin In Vivo: Multi-photon Excitation and Confocal
Microscopy, Microscopy and Microanalysis 5,
282-289 (1999).
J-270
Parasassi, T., E. Gratton, H. Zajicek,
M. Levi, and W. Yu. Detecting
membrane lipid microdomains by two-photon fluorescence microscopy. IEEE
Engineering in Medicine and Biology 18 (5), 92-99, (1999).
J-271
Fantini,
S., M. A. Franceschini, E. Gratton, D. Hueber, W. Rosenfeld, D. Maulik, P. G.
Stubblefield, and M. R. Stankovic. Non-invasive optical mapping of the piglet brain in
real time. Opt.
Express 4 (8), 308-314 (1999).
J-272
Franceschini, M. A., E. Gratton, D.
Hueber, and S. Fantini. Near-Infrared Absorption and Scattering Spectra of
Tissues in Vivo.
SPIE Biomedical Optics '99, San Jose
(CA) Vol. 3597, 526-531 (1999).
J-273
Filiaci, M., M. A. Franceschini, S.
Fantini, and E. Gratton. Photon density waves in tissues: a
study of the optical properties during changes in the oxygenation level. SPIE Biomedical Optics '99, San Jose
(CA) Vol. 3597 (1999).
J-274
Stankovic,
M. R., , D. M. Hueber, D. Maulik, P, G. Stubblefield, W. Rosenfeld, E. Gratton,
M. A. Franceschini, and S. Fantini. Real-Time Optical Imaging and Spectroscopy of Brain
Ischemia and Hemorrhage. SPIE Biomedical Optics '99,
San Jose (CA) Vol. 3597 (1999).
J-275
Toronov, V., M. Filiaci, M. A.
Franceschini, S. Fantini, and E. Gratton. Photon-density-wave
fluctuation-correlation-spectroscopy: study of coherence in the brain and
muscles.
SPIE Biomedical Optics '99, San Jose
(CA) Vol. 3597 (1999).
J-276
Lasagna,
M., E. Gratton, D. M. Jameson, and J. E. Brunet. Apohorseradish peroxidase unfolding and refolding:
Intrinsic tryptophan fluorescence studies. Biophys.
J. 76: 443-450 (1999).
J-277
Paunescu,
L. A., C. Casavola, M. A. Franceschini, S. Fantini, L. Winter, J. Kim, D. Wood
and E. Gratton. Calf muscle
blood flow and oxygen consumption measured with near-infrared spectroscopy
during venous occlusion.
SPIE Proc. 3597, Eds., B. Chance, R. R. Alfano, B. J. Tromberg, pp. 317323
(1999).
J-278
Casavola, C., L. A. Paunescu, M. A.
Franceschini, S. Fantini, L. Winter, J. Kim, D. Wood, and E. Gratton. Near-infrared spectroscopy and the tilting table
protocol: a novel method to study the blood flow and the oxygen consumption in
tissues.
SPIE Proc. 3597, Eds., Britton Chance, Robert R. Alfano, and Bruce J.
Tromberg, pp. 685-692 (1999).
J-279
Buehler,
C., C. Y. Dong, P. T. C. So, T. E. French, and E. Gratton. Frequency-domain
pump-probe microscopic imaging using intensity-modulated laser diodes In: Proc. SPIE 3603, Systems and
Technologies for Clinical Diagnostics and Drug Discovery II. G. E. Cohn, J.
C. Owicki, eds., 262271 (1999).
J-280
Franceschini, M. A., S. Fantini, V.
Toronov, M. E. Filiaci, and E. Gratton. Cerebral
hemodynamics measured by near-infrared spectroscopy at rest and during motor
activation. In Proc.
Inter-Institute Workshop on In Vivo Optical Imaging at the NIH, OSA pp.
73-80 (2000).
J-281
Bettati, S., S. Benci, B. Campanini, S.
Raboni, G. Chirico, S. Beretta, K. D. Schnackerz, T. L. Hazlett, E. Gratton,
and A. Mozzarelli. Role of pyridoxal 5'-phosphate in the structural
stabilization of 0-acetylserine sulfhydrylase. J.
Biolog. Chem. 275(51), 40244-40251 (2000).
J-282
Arcangeli, C., W. Yu, S. Cannistraro,
and E. Gratton. Two-photon autofluorescence
microscopy and spectroscopy of an Antarctic fungus: a new approach for studying
the effect of UV-B irradiation,
Biospectroscopy 57(4) 218-225 (2000).
J-283
Zolese, G., G. Falcioni, E. Bertoli, R.
Galeazzi, M. Wozniak, Z. Wypych, E. Gratton, and A. Ambrosini. Steady-state and time resolved fluorescence of
albumins interacting with noleylethanolamine, a component of the endogenous
n-acylethanolamines.
Proteins: Structure, Function, and
Genetics 40, 39-40 (2000).
J-284
Stankovic
M. R., D. Maulik, W. Rosenfeld, P. G. Stubblefield, A. D. Kofinas, E. Gratton,
M. A. Franceschini, S. Fantini, D. Hueber.
The role of
frequency domain optical spectroscopy in the detection of neonatal brain
hemorrhage - a newborn piglet study. J
Maternal Fetal Medicine 9(2), 142-149 (2000).
J-285
Chen,
Y., J. D. Müller, S. Y Tetin, J. D. Tyner and E. Gratton. Probing ligand protein binding equilibria with
fluorescence fluctuation spectroscopy. Biophys.
J. 79(2), 1074-1084 (2000).
J-286
Casavola, C,. L. A. Paunescu, S.
Fantini, M. A. and E. Gratton. Blood flow and oxygen consumption with near-infrared
spectroscopy and venous occlusion: Spatial maps and the effect of time and
pressure of inflation.
J. of Biomedical Optics 5(3), 269-276
(2000).
J-287
Parasassi, T., W. Yu, D. Durbin, L.
Kuriashkina, E. Gratton, N. Maeda and F. Ursini. Two-photon microscopy of aorta fibers shows
proteolysis induced by LDL hydroperoxides.
Free Radical Biology and Medicine
28(11), 1589-1597 (2000).
J-288
Bagatolli,
L. A., and E. Gratton, A correlation between
lipid domain shape and binary phospholipid mixture composition in free standing
bilayers. A two-photon fluorescence microscopy study, Biophys.
J. 79, 434-447 (2000).
J-289
Bagatolli,
L., E. Gratton, T. K. Khan, and P. L-G. Chong. Two-photon fluorescence microscopy studies of bipolar
tetraether giant liposomes from thermoacidophilic archaebacteria sulfolobus
acidocaldarius,
Biophys. J. 79(1), 416-425 (2000).
J-290
Buehler,
C., C. Y. Dong, P. T. So., T. French, and E. Gratton. Time-resolved polarization imaging by pump-probe
(stimulated emission) fluorescence microscopy. Biophys.
J. 79, 536-549 (2000).
J-291
Sukhishvili,
S A., Y. Chen, J.D.. Muller, E. Gratton, K.S. Schweizer, S.
Granick. Materials
science: Diffusion of a polymer 'pancake'. Nature.
406(6792):146 (2000).
J-292
Eid,
J., J. D. Müller, and E. Gratton. Data acquisition
card for FCS allowing full access to the detected photon sequence. Rev.
of Sci. Inst. 71(2), 361-368 (2000).
J-293
Bagatolli,
L. A., T. Parasassi, and E. Gratton. Giant phospholipid vesicles: comparison among the
whole lipid samples characteristics using different preparation methods. A
two-photon fluorescence microscopy study, Chemistry and Physics of Lipids
105, 135-147 (2000).
J-294
Fantini, S. and E. Gratton. Fluorescence photon-density waves in optically
diffusive media.
Optics Communications 173, 73-79
(2000).
J-295
Franceschini, M. A., V. Toronov, M.
Filiaci, E. Gratton, and S. Fantini. On-line optical imaging of the
human brain with 160-ms temporal resolution, Optics
Express 6(3), 49-57 (2000).
J-296
Frolov,
A., A. Petrescu, B. P. Atshaves, P. T. C. So, E. Gratton, G. Serrero and F.
Schroeder. High Density
Lipoprotein-mediated Cholesterol Uptake and Targeting to Lipid Droplets in
Intact L-cell Fibroblasts. A Single- and Multiphoton Fluorescence Approach. J.
Biol. Chem. 275, 12769-12780 (2000).
J-297
Müller,
J. D., Y. Chen, and E. Gratton. Resolving
heterogeneity on the single molecular level with the photon counting histogram. Biophys.
J. 78(1) 474-486 (2000).
J-298
Bagatolli,
L. A. and E. Gratton. Two photon
fluorescence microscopy of coexisting lipid domains in giant unilamellar
vesicles of binary phospholipid mixtures. Biophys.
J., 78 290-305 (2000).
J-299
Michalos,
A., L. A. Paunescu, M. Wolf, U. Wolf, V. Toronov, M. A. Franceschini, S.
Fantini, and E. Gratton. Assessment of cerebral oxygenation and hemodynamics in
obstructive sleep apnea syndrome.
SuH16, Proc. OSA Technical Digest, Biomedical
Topical Meeting (2000)
J-300
Toronov, V., M. A. Franceschini, M.
Filiaci, S. Fantini, M. Wolf, A. Michalos, and E. Gratton. Near-infrared study of fluctuations in cerebral
hemodynamics during rest and motor stimulation: Temporal analysis and spatial
mapping,
Med. Phys. 27(4), 801-815 (2000).
J-301
Franceschini, M. A., S. Fantini, V. Toronov,
M. E. Filiaci, M. P. Wolf, A. Michalos, and E. Gratton. Real-time video of brain activation in human subjects
using a non-invasive near-infrared technique. ME6, Proc. OSA Technical Digest, Biomedical Topical Meeting (2000).
J-302
Paunescu,
L. A., U. Wolf, M. Wolf, A. Michalos, and E. Gratton. Scattering coefficient-hemoglobin concentration
relation determined by frequency-domain spectroscopy during venous occlusion. TuD2. Proc. OSA Technical Digest, Biomedical Topical Meeting (2000).
J-303
Wolf,
M., V. Toronov, U. Wolf, L. A. Paunescu, A. Michalos, and E. Gratton. Maps of cerebral hemoglobin concentration changes obtained
by near-infrared spectroscopy, Characterization of phase shifts among locations. TuF6, Proc. OSA Technical Digest, Biomedical Topical Meeting, pp. 416418
(2000).
J-304
Wolf,
U., M. Wolf, V. Toronov, A. Michalos, L. A. Paunescu, and E. Gratton. Detecting cerebral functional slow and fast signals by
frequency-domain near-infrared spectroscopy using two different sensors. TuF10, Proc. OSA Technical Digest, Biomedical Topical Meeting, pp. 427-429
(2000).
J-305
Toronov,
V., M. Wolf, A. Michalos, and E. Gratton. Analysis of cerebral hemodynamic fluctuations measured
simultaneously by magnetic resonance imaging and near-infrared spectroscopy. WA5, Proc. OSA Technical Digest, Biomedical Topical Meeting (2000).
J-306
Akcakir,
O., J. Theiren, N. Barry, M. Nayfeh and E. Gratton. Detection of luminescent single ultra small silicon
nanoparticles using fluctuation correlation spectroscopy, Appl.
Phys. Lett. 76, 14 (2000).
J-307
Toronov
V, Fantini S, Franceschini MA, Filiaci M, Wolf M, Gratton E. Temporal analysis of fluctuations in cerebral
hemodynamics revealed by near-infrared spectroscopy. In:
Proc. SPIE 4001, Saratov Fall Meeting '99: Optical Technologies in
Biophysics and Medicine. V. V. Tuchin, D. A. Zimnyakov, A. B. Pravdin,
eds., 224-227 (2000).
J-308
Huang, H. C. Y. Dong, J. D. Sutin, H. S.
Kwon, G. Cragg, R. Gilbert, R. T. Lee, E. Gratton, R. D. Kamm, D.
Lauffenburger, and P. T. So. Magnetic tweezers microscope for cellular manipulation In:
Proc. SPIE 3921, Optical Diagnostics of Living Cells III. D. L. Farkas,
R. C. Leif, eds., 176-185 (2000).
J-309
Wolf,
M., M. A. Franceschini, L. A. Paunescu, V. Toronov, A. Michalos, U. Wolf, E.
Gratton, and S. Fantini. Absolute frequency-domain pulse oxymetry of the brain:
Methodology and measurements. In: Proc.
ISOTT Oxygen Transport to Tissue XXII. 27th Annual Meeting of ISOTT, J. F.
Dunn, H. M. Swartz, eds. (2000).
J-310
Toronov,
V., A. Webb, J-H. Choi, M. Wolf, and E. Gratton. Simultaneous assessment of human brain functional
hemodynamics by magnetic resonance and near-infrared imaging. In:
Proc. SPIE 4320, Medical Imaging 2001: Physics of Medical Imaging.
L. E. Antonuk, M. J. Yaffe, eds., 861-867 (2001).
J-311
Toronov,
V. Y., A. G. Webb, J. H. Choi, M. Wolf, L. P. Safonova, U. Wolf, E. Gratton.
Functional cerebral activation detected by frequency-domain near-infrared
spectroscopy. In: Proc. SPIE,
Optical Technologies in Biophysics and Medicine III; Saratov Fall Meeting,
V. V. Tuchin; ed., Vol. 4707, 92-96 (2001).
J-312
Sanchez,
S. A., Y. Chen, J. D. Mueller, E. Gratton, T. L. Hazlett. Solution and interface aggregation states of C. atrox
venom phospholipase A2 by 2-photon excitation fluorescence correlation
spectroscopy.
Biochemistry 40, 6903-6911 (2001).
J-313
Bagatolli,
L. A., and E. Gratton. Direct
observation of lipid domains in free standing bilayers using two-photon
excitation fluorescence microscopy.
J. of Fluorescence 11(3), 141-160
(2001).
J-314
Bismuto,
E., E. Gratton, and D. C. Lamb. Dynamics of ANS Binding to Tuna Apomyoglobin Measured
with Fluorescence Correlation Spectroscopy. Biophys.
J. 81, 3510-3521 (2001).
J-315
Gratton,
E., N. P. Barry, S. Beretta and A. Celli. Multiphoton Fluorescence Microscopy. Methods
25(1), 103-110 (2001).
J-316
Toronov,
V., A. Webb, J-H. Choi, M. Wolf, L. Safonova, U. Wolf and E. Gratton. Study of local cerebral hemodynamics by frequency-domain
near-infrared spectroscopy and correlation with simultaneously acquired
functional magnetic resonance imaging. Optics
Express 9(8), 417-427 (2001).
J-317
Krasnowska, E. K., L. A. Bagatolli, E.
Gratton and T. Parasassi. Surface
properties of cholesterol-containing membranes detected by Prodan
fluorescence.
BBA - Biomembranes 1511(2) 330-340
(2001).
J-318
Van
Rompaey, E., Y. Chen, J. D. Mueller, E. Gratton, E. Van Craenenbroeck, Y.
Engelborghs, S. De Smedt and J. Demeester.
Fluorescence
fluctuation analysis for the study of interactions between oligonucleotides and
polycationic polymers.
Biological Chem. 382, 379-386 (2001).
J-319
Margeat, E., N. Poujol, A. Boulahtouf,
Y. Chen, J. D. Muller, E. Gratton, V. Cavailles, and C. Royer. The Human estrogen receptor a dimer binds a single
SRC-1 coactivator molecule with an affinity dictated by agonist structure.
J. Mol. Biol. 306 (3), 433-442
(2001).
J-320
Toronov,
V., A. Webb, J. H. Choi, M. Wolf, A. Michalos, E. Gratton and D. Hueber. Investigation of human brain hemodynamics by
simultaneous near-infrared spectroscopy and functional magnetic resonance imaging. Medical
Physics 28(4) 521-527 (2001).
J-321
Chirico, G., S.Bettati, A. Mozzarelli,
Y. Chen, J. D.Müller, and E. Gratton. Molecular Heterogeneity of O-Acetylserine Sulfhydrylase
by Two-Photon Excited Fluorescence Fluctuation Spectroscopy. Biophys
J. 80(4), 1973-1985 (2001).
J-322
Dietrich,
C., L. A. Bagatolli, Z. N. Volovyk, N. L. Thompson, M. Levi, K. Jacobson, and
E. Gratton. Lipid Rafts Reconstituted in Model Membranes. Biophys. J. 80(3), 1417-1428 (2001).
J-323
Dong,
C-Y, C. Buehler, P. T. C. So, T. French, and E. Gratton. Implementation of intensity-modulated laser diodes in
time-resolved, pump-probe fluorescence microscopy. Appl.
Opt. 40, 1109-1115 (2001).
J-324
Barcellona,
M. L., Y. Chen, J. D. Müller, and E. Gratton. 4',6-diamidino-2-phenylindole
(DAPI) interacts with rare structures of GC polymers.
Eur. Biophys. J. 30 (2),
98-109 (2001).
J-325
Nayfeh,
M. H., J. Therrien, G. Belomoin, A. Akcakir, N. Barry, and E. Gratton. Stimulated blue emission and second
harmonic generation from films of ultrasmall Si nanoparticles. In: Proc.
Materials Research Society Symposium, V. 638 F951-F9512 (2001).
J-326
Ragan,
T., P. T. C. So, H-S.Kwon, and E. Gratton. 3D particle tracking on the two-photon microscope In:
Proc. SPIE 4262, Multiphoton Microscopy in the Biomedical Sciences. A.
Periasamy, P. T. So, eds., 247-258 (2001).
J-327
Toronov,
V., A. Webb, J. H. Choi, M. Wolf, E. Gratton, and D. M. Hueber. Simultaneous functional magnetic resonance and
near-infrared imaging of adult human brain. In:
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV.
B. Chance, R. R. Alfano, B. J. Tromberg, M. Tamura, E. M. Sevick-Muraca, eds.
380-382 (2001).
J-328
Paunescu,
L. A., A. Michalos, J. H. Choi, U. Wolf, M. Wolf, and E. Gratton. In vitro correlation between reduced scattering
coefficient and hemoglobin concentration of human blood determined by
near-infrared spectroscopy.
In: Proc. SPIE Proc. 4250, BIOS 2001;
Internatonal Biomedical Optics Symposium. Optical Tomography and Spectroscopy
of Tissue IV. B.Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M.
Sevick-Muraca, eds., 319-326 (2001).
J-329
Ruan,
Q., Y. Chen, E. Gratton, M. Glaser and W. W. Mantulin. Cellular characterization of adenylate kinase and its
isoform; Two-photon excitation fluorescence imaging and fluorescence
correlation spectroscopy.
Biophys. J. 83 (6), 3177-3187 (2002).
J-330
Hanson,
K.M., M. J. Behne, N. P. Barry, T. M. Mauro, E. Gratton, and R. M. Clegg. Two-photon fluorescence lifetime imaging of the skin
stratum corneum pH gradient.
Biophys J. 83(3), 1682-1690 (2002).
J-331
Wolf,
M., U. Wolf, J.H. Choi, R. Gupta, L. P. Safonova, L. A. Paunescu, A. Michalos
and E. Gratton. Functional
Frequency-Domain Near-Infrared Spectroscopy Detects Fast Neuronal Signal in the
Motor Cortex,
NeuroImage 17(4), 1868-1875 (2002).
J-332
Wolf,
M., U. Wolf, V. Toronov, A. Michalos, L. A. Paunescu, J-H. Choi and E. Gratton.
Different time
evolution of oxyhemoglobin and deoxyhemoglobin concentration changes in the
visual and motor cortices during functional stimulation: A near-infrared
spectroscopy study.
NeuroImage 16, 704-712 (2002).
J-333
Bettati, S., B.Campanini, S. Vaccari, A.
Mozzarelli, G. Schianchi, T. L. Hazlett, and E. Gratton. Unfolding of pyridoxal 5'-phosphate-dependent
O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence. Biochim.
Biophys. Acta 1596(1), 47-54 (2002).
J-334
Tricerri, M A., S. A. Sanchez, C.
Arnulphi, D. M. Durbin, E. Gratton, A. Jonas. Interaction of apolipoprotein A-I in three different
conformations with palmitoyl oleoyl phosphatidylcholine vesicles, J.
of Lipid Research 43(2), 187-197 (2002).
J-335
Patel,
R. C; U. Kumar, D. C. Lamb, J. S. Eid, M. Rocheville, M. Grant, A. Rani, T.
Hazlett, S. C. Patel, E. Gratton, Y. C. Patel. Ligand binding to somatostatin receptors induces
receptor-specific oligomer formation in live cells. Proc.
of the National Academy of Sciences of the USA 99(5), 32943299 (2002).
J-336
Fahsel,
S., E.-M. Pospiech, M. Zein, T. L. Hazlet, E. Gratton, and R. Winter. Modulation of Concentration Fluctuations in
Phase-Separated Lipid Membranes by Polypeptide Insertion. Biophys.
J. 83, 334-344 (2002).
J-337
Behne,
M.J., J. W. Meyer, K. M. Hanson, N. P. Barry, S. Murata, D. Crumrine, R. W.
Clegg, E. Gratton, W. M. Holleran, P. M. Elias, and T. M. Mauro. NHE1 regulates the stratum corneum permeability
barrier homeostasis. Microenvironment acidification assessed with fluorescence
lifetime imaging.
J Biol Chem. 277(49):47399-47406
(2002).
J-338
Sanchez,
S.A., L. A. Bagatolli, E. Gratton, and T. L. Hazlett. A Two-Photon View of an Enzyme at Work: Crotalus atrox
Venom PLA2 Interaction with Single-Lipid and Mixed-Lipid Giant Unilamellar
Vesicles.
Biophys. J. 82, 2232-2243 (2002).
J-339
Chen, Y., J. D. Müller, Q.Q. Ruan, and
E. Gratton. Molecular
Brightness Characterization of EGFP in Vivo by Fluorescence Fluctuation
Spectroscopy.
Biophys. J. 82, 133-144 (2002).
J-340
Sukhishvili, S. A., Y. Chen, J.D.
Muller, E. Gratton, K. S. Schweizer, S. Granick. Surface Diffusion of Poly(ethylene
glycol).
Macromolecules 35(5), 1776-1784
(2002).
J-341
Barry,
N. P., K. M. Hanson, E. Gratton, R. M. Clegg, M. J. Behne, and T. Mauro. Applications of ultrafast lasers to two-photon
fluorescence and lifetime imaging.
In: Proc. SPIE 4633, Commercial
and Biomedical Applications of Ultrafast and Free-Electron Lasers. G. S.
Edwards, J. Neev, A. Ostendorf, J. C. Sutherland, eds., 50-61 (2002).
J-342
Morren,
G., M. Wolf, P. Lemmerling, U. Wolf, J. H. Choi, E. Gratton, L. De Lathauwer,
and S. Van Huffel. Extraction of
fast neuronal changes from multichannel functional near-infrared spectroscopy
signals using independent component analysis. In:
Proc. SPIE 4623 , Functional Monitoring and
Drug-Tissue Interaction. M. D. Kessler, G. J. Mueller; eds., 68-76 (2002).
J-343
Toronov,
V., E. D'Amico, D. Hueber, E. Gratton, B. Barbieri, A.Webb. Optimization of the signal-to-noise ratio of
frequency-domain instrumentation for near-infrared spectro-imaging of the human
brain.
Optics Express 11(21), 2717-2729
(2003).
J-344
Levi, V., Q. Ruan, K. Kis-Petikova and
E. Gratton. Scanning FCS, a
novel method for three-dimensional particle tracking. Biochem.
Soc. Transactions 31(5), 997-1000 (2003).
J-345
Toronov,
V., A. Webb, S. Walker, R. Gupta, J. H. Choi, E. Gratton, and D. M. Hueber. Study of the FMRI blood oxygen level dependent effect
by near-infrared spectroscopy. In: Proc.
SPIE Int. Soc. Opt. Eng. 5068, 222 (2003).
J-346
Gratton,
E., Scanning FCS: measuring spatio-temporal
correlations in the millisecond range. In: Proc.
SPIE, Vol. #4963, San Jose, CA (2003).
J-347
Gaus,
K., E. Gratton, E. P. W. Kable, A. S. Jones, I. Gelissen, L. Kritharides, and
W. Jessup. Visualizing lipid structure and
raft domains in living cells with two-photon microscopy. Proc.
Nat. Acad. Sci. 100, 15554-15559 (2003).
J-348
Muller,
J. D. and E. Gratton. High-pressure
fluorescence correlation spectroscopy. Biophys.
J. 85, 2711-2719 (2003).
J-349
Wolf,
U., M. Wolf, J. H. Choi, M. Levi, D. Choudhury, S. Hull, D. Coussirat, L. A.
Paunescu, L. P. Safonova, A. Michalos, W. W. Mantulin and E. Gratton. Localized irregularities in hemoglobin flow and
oxygenation in the calf muscle in patients with peripheral vascular disease
detected by near-infrared spectrophotometry.
J. Vasc. Surgery 37, 1017-1026 (2003).
J-350
Toronov.
V. S. Walker, R. Gupta, J. H. Choi, E. Gratton, D. Hueber and A. Webb. The roles of changes in deoxyhemoglobin concentration
and regional cerebral blood volume in the fMRI BOLD signal. NeuroImage
19 (4), 1521-1531(2003).
J-351
Gratton,
E., S. Breusegem, J. Sutin, Q. Ruan and N. Barry. Fluorescence lifetime imaging for the two-photon
microscope: Time-domain and frequency-domain methods. J.
of Biomedical Optics 8(3), 381-390 (2003).
J-352
Wolf,
M., M.A. Franceschini, L.A. Paunescu, V.
Toronov, A. Michalos, U. Wolf, E. Gratton and S. Fantini. Absolute frequency-domain pulse
oximetry of the brain: Methodology and measurements. Adv
Exp Med Biol. 530: 61-73 ( 2003).
J-353
Behne,
M. J. N.P. Barry, K. M. Hanson, I. Aronchik, R. W. Clegg, E. Gratton, K.
Feingold, W. M. Holleran, P.M. Elias, T.M. Mauro. Neonatal development of the Stratum Corneum pH
gradient: localization and mechanisms leading to emergence of optimal barrier
function.
J of Invest. Dermatology. 120(6),
998-1006, 2003.
J-354
Wolf,
M., U. Wolf J.H. Choi, V. Toronov, L. A. Paunescu, A. Michalos, and E. Gratton.
Fast cerebral functional signal in the 100ms range
detected in the visual cortex by frequency-domain near-infrared spectroscopy. Psychophysiology
40, 521-528 (2003).
J-355
Wolf,
M., U. Wolf, J. H. Choi, R. Gupta, L. P. Safonova, L. A. Paunescu, A. Michalos
and E. Gratton. Detection of the fast neuronal signal
on the motor cortex using functional frequency domain near infrared
spectroscopy.
Adv. Exp. Med. Biol. 510, D. F.
Wilson, S. M. Evans, J. Biaglow, A. Pastuszko, eds., 193-197 (2003).
J-356
Wolf,
U., M. Wolf, J. H. Choi, L. A. Paunescu, A. Michalos, L. Safonova and E.
Gratton. Mapping of
hemodynamics with near infrared spectroscopy of the human calf tissue and the
influence of the adipose tissue thickness. Adv.
Exp. Med. Biol. D. F. Wilson, S. M. Evans, J. Biaglow, A. Pastuszko, eds.,
225-230 (2003).
J-357
Best,
K. B., A. J. Ohran, A. C. Hawes, T. L. Hazlett, E. Gratton, A. M. Judd, and J.
D. Bell. Relationship
between erythrocyte membrane phase properties and susceptibility to secretory
phospholipase A2.
Biochemistry 41(47), 13982-13988
(2003).
J-358
Zamai, M., M. VandeVen, M. Farao, E.
Gratton, A. Ghiglieri, M. G. Castelli, E. Fontana, R. D'Argy, A. Fiorino, E.
Pesenti, A. Suarato, V. R. Caiolfa. Camptothecin
poly[n-(2-hydroxypropyl) methacrylamide] copolymers in antitopoisomerase-I
tumor therapy: intratumor release and antitumor efficacy. Mol Cancer Ther. 2(1),
29-40 (2003).
J-359
Safonova
L.P., A. Michalos, U. Wolf, M. Wolf, W.W. Mantulin, D.M. Hueber and E. Gratton.
Diminished cerebral circulatory
autoregulation in obstructive sleep apnea investigated by near-infrared
spectroscopy.
Sleep Research On-line 5(4), 126-132
(2003).
J-360
Barcellona, M.
L., S. Gammon, T. Hazlett, M. Digman and E. Gratton. Polarized fluorescence correlation spectroscopy of
DNA-DAPI complexes. Microscopy
Res. and Tech. 65(4-5), 205-217 (2004).
J-361
Inoue, M., M. A.
Digman, M. Cheng, S. Y. Breusegem, N. Halaihel, V. Sorribas, W. W. Mantulin, E.
Gratton, N. P. Barry and M. Levi. Partitioning of
NaPi cotransporter in cholesterol, sphingomyelin and glycosphingolipid enriched
membrane domains modulates NaPi protein diffusion, clustering and activity. J Biol. Chem. 279 (47) 49160–49171 (2004).
J-362
Czeslik, C., G. Jackler, T. Hazlett, E. Gratton, R.
Steitz, A. Wittemann and M. Ballauff. Salt-induced protein resistance of polyelectrolyte
brushes studied using fluorescence correlation spectroscopy and neutron
reflectometry. Phys . Chem. Chem. Phys. 6, 5557–5563 (2004).
J-363
Janosch, S., C.
Nicolini, B. Ludolf, C. Peters, M. Volkert, T.L. Hazlett, E. Gratton, H.
Waldmann and R. Winter. Partitioning of
dual-lipidated peptides into membrane microdomains - lipid sorting vs. peptide
aggregation. J. Amer.
Chem. Soc. 126(24), 7496-7503 (2004).
J-364
Rao, S., J. Sutin,
R. Clegg, E. Gratton, M. H. Nayfeh, S. Habbal, A. Tsolakidis and R. M. Martin. Excited states of tetrahedral single-core Si29
nanoparticles. Phys. Rev.
B 69, 205319 (2004).
J-365
Safonova L.P., A.
Michalos, U. Wolf, M. Wolf, D.M. Hueber, J.H. Choi, R. Gupta, C. Polzonetti,
W.W. Mantulin and E. Gratton. Age-correlated changes in cerebral
hemodynamics assessed by near-infrared spectroscopy. Archives of Gerontology and Geriatrics
39(3), 207-225 (2004).
J-366
Ruan,
Q., M. A. Cheng, M. Levi, E. Gratton and W. W. Mantulin. Spatial-temporal studies of membrane dynamics:
scanning fluorescence correlation spectroscopy (SFCS).
Biophys J 87, 12601267
(2004).
J-367
Czeslik,
C., R. Jansen, M. Ballauff, A. Wittmann, C. A. Royer, E. Gratton and T.
Hazlett. Mechanism of protein binding to
spherical polyelectrolyte brushes studied in situ using two-photon excitation
fluorescence fluctuation spectroscopy. Phys.
Rev. E 69, 021401-021409 (2004).
J-368
Morren,
G., U. Wolf, P. Lemmerling, M. Wolf, J.H. Choi, E. Gratton, L. De Lathauwer and
S. Van Huffel. Detection of
fast neuronal signals in the motor cortex from functional near infrared
spectroscopy measurements using independent component analysis.
Med. Biol. Eng. Comp. 42(1), 92-99 (2004).
J-369
Kis-Petekova,
K. and E. Gratton. Distance
Measurement by Circular Scanning of the Excitation Beam in the Two-Photon
Microscope.
Microsc Res Tech 63 (1), 34-49
(2004).
J-370
Choi,
J.H., W. Wolf, V. Toronov, U. Wolf, C. Polzonetti, L.P. Safonova, A. Michalos,
W.W. Mantulin and E. Gratton, Noninvasive
determination of the optical properties of the adult brain: Near infrared
spectroscopy approach
J. Biomed. Optics, 9(1) 221-229
(2004).
J-371
Tanner, K. and E.
D’Amico, A. Kaczmarowski, S. Kukreti, J. Malpeli, W. W. Mantulin and E.
Gratton. Spectrally resolved
neurophotonics: A case report of hemodynamics and vascular components in the
mammalian brain. J. of
Biomed. Optics 10, 064009-1-9 (2005).
J-372
Levi, V., Q.
Ruan, M. Plutz, A. S. Belmont, and E. Gratton. Chromatin dynamics in interphase cells revealed by
tracking in a two-photon excitation microscope. Biophys. J. 89, 4275–4285 (2005).
J-373
Gokhale, N. A.,
A. Abraham, M. A. Digman, E. Gratton, and W. Cho. Phosphoinositide specificity of and mechanism of lipid
domain formation by annexin A2-p11 heterotetramer. J. Biol. Chem. 280(52), 42831-42840 (2005).
J-374
Eckhoff, D. A.,
J. D. B. Sutin, R. M. Clegg, E. Gratton, E. V. Rogozhina, P. V. Braun. Optical Characterization of Ultrasmall Si
Nanoparticles Prepared through Electrochemical Dispersion of Bulk Si. J. Phys. Chem. B , 109(42), 19786-19797 (2005).
J-375
Digman, M. A., C.
M. Brown, P. Sengupta, P. W. Wiseman, A. R. Horwitz and E. Gratton. Measuring Fast Dynamics in Solutions and Cells with a
Laser Scanning Microscope. Biophys. J.
89, 1317-1327 (2005).
J-376
Digman, M. A., P.
Sengupta, P. W. Wiseman, C. M. Brown, A. R. Horwitz, and E. Gratton. Fluctuation Correlation Spectroscopy with a
Laser-Scanning Microscope: Exploiting the Hidden Time Structure. Biophys. J. Biophysical Letters: 88:
L33-36L (2005).
J-377
Arnulphi, C., S.
A. Sánchez, M. A.Tricerri, E. Gratton and A. Jonas. Interaction of Human Apolipoprotein A-I with Model
Membranes Exhibiting Lipid Domains. Biophys.
J. 89, 285-295 (2005).
J-378
Sanchez, S. A.
and E. Gratton. Lipid-protein
interactions revealed by two-photon microscopy and fluorescence correlation
spectroscopy. Acc. Chemical
Research 38, 469-477 (2005).
J-379
Levi, V., Q.
Ruan, and E. Gratton. 3-D Particle
Tracking in a Two-Photon Microscope: Application to the Study of Molecular
Dynamics in Cells. Biophys.
J. 88, 2919-2928 (2005).
J-380
Gratton, E., V.
Y. Toronov, U. Wolf, M. Wolf, A. G. Webb. Measurement of brain activity by near-infrared light. J. Biomedical Optics 10(01), 1-13 (2005).
J-381
Tricerri M.A., J.
D. Toledo, S. A. Sanchez, T. L. Hazlett, E. Gratton, A. Jonas and H. A. Garda. Visualization and analysis of apolipoprotein A-I
interaction with binary phospholipid bilayers. J. Lipid Res. 46(4), 669-678 (2005).
J-382
Hanson, K., E.
Gratton, and C. J. Bardeen. Sunscreen
enhancement of UV-induced reactive oxygen species in the skin. Free Radic Biol Med 41(8):1205-12 (2006).
J-383
Nicolini, C., A. Celli, E. Gratton, and R. Winter. Pressure tuning of the
morphology of heterogeneous lipid vesicles: a two-photon-excitation
fluorescence microscopy study. Biophys J 91(8):2936-42 (2006).
J-384
Eckhoff, D.A., J.
N. Stuart, J. D. B. Sutin, J. V. Sweedler, and E. Gratton. Capillary
electrophoresis of ultrasmall carboxylate functionalized silicon nanoparticles. J Chem Phys 125(8):081103 (2006).
J-385
Rogozhina, E. V.,
D. A. Eckhoff, E. Gratton and P. V. Braun. Carboxyl
functionalization of ultrasmall luminescent silicon nanoparticles through
thermal hydrosilylation. J.
Materials Chemistry 16, 1421-1430 (2006).
J-386
Nicolini, C., J.
Baranski, S. Schlummer, J. Palomo, M. Lumbierres-Burgues, M. Kahms, J.
Kuhlmann, S. Sanchez, E. Gratton, H. Waldmann and R. Winter. Visualizing association
of N-Ras in lipid microdomains: Influence of domain structure and interfacial
adsorption. JACS,
192-201 (2006).
J-387
Simonson, P., E.
D’Amico and E. Gratton. Modulation of an optical
needle’s reflectivity alters the average photon path through scattering media. J. Biomedical Optics, 11(1) 014023-1-9
(2006).
J-388
Ragan, T., H.
Huang, P. So and E. Gratton. 3D particle tracking on
a two-photon microscope. J.
Fluorescence (2006).
J-389
Levi, V., V. I.
Gelfand, A. S. Serpinskaya and E. Gratton. Melanosomes
Transported by Myosin V in Xenopus Melanophores Perform Slow 35 nm Steps. Biophys. J. (2006).
J-390
Levi, V., A. S
Serpinskaya, E. Gratton, and V. Gelfand. Organelle transport along microtubules in
Xenopus melanophores: evidence for cooperation between multiple motors. Biophys. J. 90, 318-327
(2006).
J-391
V R Caiolfa, M Zamai,
G Malengo, A Andolfo, C D Madsen, J D B Sutin, M A
Digman, E Gratton, F Blasi, and N Sidenius. Monomer–dimer dynamics and distribution of
GPI-anchored uPAR are determined by cell surface protein assemblies. J Cell Biol
2007; 179(5): 1067-1082.
J-392
C O Olopade, E Mensah, R Gupta, D Huo, D L Picchiett, E
Gratton, and A Michalos. Noninvasive
determination of brain tissue oxygenation during sleep in obstructive sleep
apnea: a near-infrared spectroscopic approach. Sleep
2007; 30(12): 1747-1755.
J-393
U Wolf, M Wolf,
J-H Choi, L A Paunescu, A Michalos, and E Gratton. Regional differences of hemodynamics and
oxygenation in the human calf muscle detected with near-infrared
spectrophotometry. J Vasc Interv Radiol 2007; 18(9):
1094-1101.
J-394
R Gatto, W
Hoffman, C Paisansathan, W W Mantulin, E Gratton, and F T Charbel. Effect of age on brain
oxygenation regulation during changes in position. J Neurosci
Methods 2007; 164(2): 308-311.
J-395
S A Sánchez, M A
Tricerri, and E Gratton. Interaction of high
density lipoprotein particles with membranes containing cholesterol. J Lipid Res 2007;
48(8): 1689-1700.
J-396
V Levi and E Gratton. Exploring dynamics in living cells by
tracking single particles. Cell Biochem Biophys 2007; 48(1):
1-15.
J-397
S Kukreti, A Cerussi, B Tromberg, and E Gratton. Intrinsic tumor
biomarkers revealed by novel double-differential spectroscopic analysis of
near-infrared spectra. J Biomed Opt 2007; 12(2): 020509.
J-398
N Boens, W Qin, N
Basari, J Hofkens, M Ameloot, J Pouget, J-P Lefèvre, B Valeur, E Gratton, M
vandeVen, N D Silva, Jr, Y Engelborghs, K Willaert, A Sillen, G Rumbles, D
Phillips, A J W G Visser, A van Hoek, J R Lakowicz, H Malak, I Gryczynski, A G
Szabo, D T Krajcarski, N Tamai, and A Miura. Fluorescence lifetime standards for time
and frequency domain fluorescence spectroscopy. Anal Chem
2007; 79(5): 2137-49.
J-399
M Calderon-Arnulphi,
A Alaraj, S Amin-Hanjani, W W Mantulin, C M Polzonetti, E Gratton, and F T
Charbel. Detection
of cerebral ischemia in neurovascular surgery using quantitative
frequency-domain near-infrared spectroscopy. J Neurosurg
2007; 106(2): 283-290.
J-400
K Tanner, E Beitel, E D'Amico, W W Mantulin, and E
Gratton. Effects
of vasodilation on intrinsic optical signals in the mammalian brain: a phantom
study. J Biomed Opt 2007; 11(6): 064020.
J-401
G
Malengo, A Andolfo, N Sidenius, E Gratton, M Zamai,
and V R Caiolfa. Fluorescence correlation spectroscopy and photon
counting histogram on membrane proteins: functional dynamics of the
glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor. J Biomed Opt 2008; 13(3): 031215.
J-402
V Levi and E Gratton. Chromatin dynamics during interphase explored by single-particle tracking. Chromosome Res 2008; 16(3): 439-449.
J-403
S
Kwok, C Y Lee, S A Sánchez, T L Hazlett, E Gratton, and Y Hayashi. Genetically
encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochem Biophys Res Commun 2008; 369(2): 519-525. PMCID: PMC2396457
J-404
M A
Digman, C M Brown, A R Horwitz, W W Mantulin, and E
Gratton. Paxillin dynamics measured during adhesion assembly
and disassembly by correlation spectroscopy. Biophys J 2008; 94(7): 2819-2831.
J-405
A Garcia-Marcos, S A Sánchez, P Parada, J S
Eid, D M Jameson, M Remacha, E Gratton, and J P G Ballesta. Yeast ribosomal stalk heterogeneity in vivo shown by two-photon FCS and
molecular brightness analysis. Biophys J 2008; 94(7): 2884-2890.
J-406
M A Digman, R Dalal, A R Horwitz, and E
Gratton. Mapping the number of molecules and brightness in
the laser scanning microscope. Biophys J
2008; 94(6): 2320-2332.
J-407
C B
Raub, J R Unruh, V Suresh, T Krasieva, T Lindmo, E Gratton, B J Tromberg, and S
C George. Image correlation spectroscopy of multiphoton images
correlates with collagen mechanical properties. Biophys J 2008; 94(6): 2361-2373.
J-408
R A
Colyer, C Y Lee, and E Gratton. A novel fluorescence lifetime imaging system that optimizes photon
efficiency. Microsc Res Tech 2008; 71(3): 201-213.
J-409
S A Sánchez,
M A Tricerri, and E Gratton. Detecting
cholesterol changes in lipid bilayers. BioWorld Europe 2008; 1:
8-11.
J-410
M A
Digman, V R Caiolfa, M Zamai, and E Gratton. The Phasor approach to fluorescence lifetime imaging
analysis. Biophys J
2008; 94(2): L14-16.
J-411
R Fiorini, L Ragni, S Ambrosi, G P Littarru,
E Gratton, and T Hazlett. Fluorescence studies of the interactions of
ubiquinol-10 with liposomes. Photochem Photobiol 2008; 84(1): 209-214.
J-412
R B
Dalal, M A Digman, A R Horwitz, V Vetri, and E
Gratton. Determination of particle number and brightness
using a laser scanning confocal microscope operating in the analog mode. Microsc Res Tech 2008; 71(1): 69-81.
J-413
A Celli, S Beretta, and E Gratton. Phase fluctuation on the micron-submicron scale in GUVs composed of a
binary lipid mixture. Biophys J
2008; 94(1): 104-116.
J-414
C M
Brown, R B Dalal, B Hebert, M A Digman, A R Horwitz,
and E Gratton. Raster image correlation spectroscopy (RICS) for measuring fast protein
dynamics and concentrations with a commercial laser scanning confocal
microscope. J Microsc
2008; 229(1): 78-91.
J-415
H Sanabria, M A Digman, E Gratton, and M N
Waxham. Spatial
Diffusivity and availability of intracellular Calmodulin. Biophys
J 2008 [epub ahead of print].
J-416
J R
Unruh and E Gratton. Analysis of
molecular concentration and brightness from fluorescence fluctuation data with
an electron multiplied CCD camera. Biophys J
2008; [epub ahead of
print].
J-417
C
Hellriegel and E Gratton. Real-time
multi-parameter spectroscopy and localization in three-dimensional
single-particle tracking. J R Soc Interface 2008;
[epub ahead of print].
J-418
M A
Digman, P W Wiseman, A R Horwitz, and E Gratton. Detecting protein complexes in living cells
from laser scanning confocal image sequences by the ccRICS method. Biophys
J 2008 [accepted].
J-419
M A Digman, E Gratton. Analysis of diffusion and binding in cells
using the RICS approach. Microsc Res Tech 2008;
[accepted].
J-420
S
Kukreti, A Cerussi, B Tromberg, and E Gratton. Intrinsic near-infrared spectroscopic
markers of breast tumors. Disease Markers (IOS Press), 2008
[accepted].
J-421
M
Digman and E Gratton.
Fluorescence Correlation Spectroscopy and Fluorescence Cross-Correlation
Spectroscopy. Wiley Interdisciplinary
Reviews: Systems Biology and Medicine 2009 [accepted].
J-422
M A
Digman, P W Wiseman, C K Choi, A R Horwitz, and E
Gratton. Mapping the stoichiometry of molecular complexes at
adhesions in living cells. Proc Natl Acad Sci USA. 2008; [submitted].
J-423
K
Tanner, D R Ferris, L Lanzano, B Mandefro, W W Mantulin, D M Gardiner, E Rugg,
and E Gratton.
Image Correlation Spectroscopy Reveals Global Dynamics of Wound Healing. J
Fed Amer Soc Exp Biol. 2008; [in preparation].
J-424
Ellen
Gielen, Nick Smisdom, Martin J vandeVen, Ben De Clercq, Enrico Gratton,
Michelle A Digman, Jean-Michel Rigo, Johan Hofkens, Yves Engelborghs, and
Marcel Ameloot. Measuring diffusion of lipid-like probes in
artificial and natural membranes by raster image correlation spectroscopy
(RICS): Use of a commercial laser-scanning microscope with analog detection. Langmuir. 2009; [epub ahead of print].
Conference Presentations
CP-1
Gratton, E., Invited Speaker: 2nd Annual Workshop on Advanced Optical
Methods: Molecular Machines to Cells, Molecular Imaging Center, University of
California, Berkeley. January 20-21, 2005.
CP-2
Ko, W. S., N.
Darwish, E. Gratton, S. H. Kim, Development of the scanning system to detect
the concentration of the oxy- and deoxy-hemoglobin by tracking the head. Poster
5686-119. SPIE Meeting, San Jose, California, January, 22-27, 2005.
CP-3
Gratton, E.,
"NIRS measures brain vasoreactivity." Invited Seminar, Cognitive
Imaging Laboratory, Beckman Institute, February 2005.
Biophysical
Society Meeting, California, February, 2005
CP-4
Digman, Michelle
A., Makoto Inoue, Melanie Cheng, Sophia Y. Breusegem, Nabil Halaihel, Victor
Sorribas, William W. Mantulin, Enrico Gratton, Nicholas P. Barry, Moshe Levi.
Partitioning of NaPi Cotransporter in Cholesterol, Sphingomyelin and
Glycosphingolipid Enriched Membrane Domains Modulates NaPi Protein Diffusion,
Clustering and Activity.
CP-5
Sengupta, Parijat, Michelle Digman, Enrico Gratton. Scanning Image
Correlation Spectroscopy Reveals Fast Molecular Dynamics.
CP-6
Colyer, Ryan A., Jason D. B. Sutin, Bryant B. Chhun,
Enrico Gratton. Spatial Resolution Enhancement using Non-Linear Temporal
Cross-Correlation Techniques in Pump-Probe Confocal Microscopy.
CP-7
Celli, Anna, Claudia Lee, Enrico Gratton. High
hydrostatic pressure induced shape and lipid phase changes on Giant Unilamellar
Vesicles studied with two-photon excitation microscopy.
CP-8
Digman, Michelle
A., Claire M. Brown, Alan R. Horwitz, Parijat Sengupta, William W. Mantulin,
Enrico Gratton. Spatio-temporal fluorescence fluctuation analysis of
paxillin-EGFP in cellular adhesions using scanning FCS, ICS and PCH.
CP-9
Czeslik,Claus ,Theodore Hazlett, Enrico Gratton, Roland Steitz,
Hans-Hennig von Grünberg, Matthias Ballauff. Effect of salt on the
immobilization of proteins at polyelectrolyte brushes
CP-10 Gomes, Andre M. O., Andrea C. Oliveira, Valeria Levi,
Rafael B. Goncalves, Umesh Katpally, Thomas J. Smith, Enrico Gratton. Real Time
3D Tracking of Virus Particles in Live Cell
CP-11 Levi, Valeria, Andrew Belmont, Matthew Plutz, Enrico
Gratton. Dynamics of a DNA Sequence in Interphase Cells Revealed by
Fast-tracking in a Two-photon Microscope
CP-12 Malengo, Gabriele, Annapaola Andolfo, Parijat
Sengupta, Shih Chu Liao, Beniamino Barbieri, Giuseppe Chirico, Enrico Gratton,
Francesco Blasi, Nicolai Sidenius, Valeria R. Caiolfa. The GPI-anchored
Urokinase Receptor (uPAR) dynamics on the cells surface followed by
fluorescence fluctuation spectroscopy.
CP-13 Tahari, Abdel K. Guido
Motolese, Enrico Gratton. Fluorescence correlation spectroscopy in turbid media:
Ultrasensitive detection of bacteria, viruses, and protein aggregates.
CP-14 Hazlett, Theodore L., Marisa Barcellona, Michelle
Digman, Enrico Gratton, Polarized FCS: detection of rotational motions of
macromolecules
CP-15
Gratton, E.,
"FCS," Hamamatsu Special Seminar, Rockville, MD, March 16, 2005.
CP-16
Gratton, E.,
"FCS," Hamamatsu Special Seminar, Bridgewater, NJ, March 17, 2005.
CP-17
Sutin, J., S.
Awtar, J. Hart, A.H. Slocum, E. Gratton. "Improving the performance of the
optical microscope via modern opto and optomechanical design." Focus on
Microscopy, Jena, Germany , March 20-23, 2005.
CP-18
Lera, M., J.
Sutin, J.F. Aguilar, E. Gratton. "Confocal profiling of spherical
cavities." Focus on Microscopy, Jena, Germany ,
March 20-23, 2005.
CP-19
Gratton, E.,
"Tracking Molecules in Cells using a Two-photon Microscope." Chemical
Biophysics Mini-Symposium, University of Pennsylvania, April 21, 2005.
CP-20
Gratton, E.,
"Brain vasoreactivity by near-ir optical spectroscopy." 2005 Industry
Research Symposium, Irvine, CA, May, 2005.
CP-21
Gratton, E. and
K. Tanner: Second Annual Breast Cancer Imaging Network Retreat and Workshop,
Newport Beach, California, June 2-4, 2005.
CP-22
Gratton E., and
S. Sanchez, FCS, Generalized Polarization and
other techniques to probe the membrane organization. INSERM workshop on
"Dynamic and functional imaging of live cells: from the detection of
singles molecules to the visualization of tissues" June, 2005.
CP-23
Gratton, E.,
INSERM and the French Society of Cell Biology, Marseille, France
, June 29-July 2, 2005.
CP-24
Gratton, E.,
Steering Committee, 9th International Conference on Methodsand Applications
ofFluorescence Spectroscopy, Imaging and Probes. Libson, Portugal
, September 4-7, 2005.
CP-25
Gratton, E.,
Instructor, Principles of Fluorescence Techniques, Laboratory for Advanced
Microscopy, Bioimaging and Spectroscopy, Genova, Italy ,
September 13-14, 2005.
CP-26
Gratton, E.,
"Fluctuation dynamics of the cell interior." First European
Conference on Chemistry for Life Sciences. Rimini, Italy ,
October 4-8, 2005.
CP-27
Gratton, E.,
"Looking into the Brain with Lasers." Saturday Physics Honors Program
Seminar, University of Illinois at Urbana-Champaign, October 15, 2005.
CP-28
Barry, N. M. Digman, C. Lee, S. Y.
Breusegem, W. W. Mantulin, E. Gratton, M. Levi, "The Heterogeneity of NaPi Protein Dynamics and
NaPi Cotransport Activity in Rat Brush Border Membranes" Meeting of
American Society of Nephrology, Pennsylvania Convention Center, Philadelphia,
Pennsylvania, November 8-13, 2005.
CP-29
Gratton, E.,
"Probing Single Molecule Diffusion and Clustering with Fluorescence
Correlation Spectroscopy (FCS) and Photon Counting Histogram (PCH),"
Invited Speaker, American Society of Nephrology, Renal Week 2005, Pennsylvania
Convention Center, Philadelphia, PA, November 8–13,
2005.
CP-30
Gratton, E.,
Invited Speaker, Department of Biology Seminar Series, December 1, 2005
CP-31
Gratton, E., A
New Approach to FLIM Analysis. Advanced Optical Methods Workshop 2006,
Berkeley, CA, January 19-20, 2006.
CP-32
Gratton, E.,
Department of Biology Seminar Series, John Hopkins University, February 16,
2006.
Biophysical
Society, February 18-22, 2006.
CP-33 Gratton, E., 3-D particle tracking using a two-photon
excitation microscope, Invited Speaker, Analyzing Submicrometer Structure and
Motion in Light Microscopy Workshop.
CP-34 Toro, C. A., A.
Zanocco, G. Gunther, E. Gratton, S. A. Sanchez. Detergent
solubilization of lipid bilayers followed by 2-photon microscopy.
(276-Pos/B142)
CP-35 Levi, V., A. S. Serpinskaya, V. Gelfand, E. Gratton.
Single particle tracking study of organelles transport in Xenopus
Melanophores. (647-Pos/B513)
CP-36 Gratton, E., M. A.
Digman. Ultrafast analysis of fluorescence lifetime images
using the phasor approach: application to FRET analysis. (681-Pos/B547)
CP-37 Colyer, R. A., C. Y. C.
Lee, E. Gratton. Frequency-Domain Fluorescence Lifetime Imaging
Microscopy in the Photon-Counting Regime with Field-Programmable Gate Arrays.
(684-Pos/B550)
CP-38 Lee, C. Y. C., E.
Gratton. Fluctuation Correlation Spectroscopy with Colloidal
Gold Particles. (685-Pos/B551)
CP-39 Hazlett, T. L., E.
Gratton. Characterization of Particle Angular Fluctuations by
Intensity and Polarization Trajectory Plots. (691-Pos/B557)
CP-40 Digman, M. A., C. M. Brown, A. F. Horwitz, W. W.
Mantulin, E. Gratton. Fast dynamics in the cell interior revealed by
RICS. (699-Pos/B565)
CP-41 Gomes, A. O., A. C. Oliveira, V. Levi, R. B.
Goncalves, U. Katpally, T. J. Smith, E. Gratton. New insights on
transport and particle dynamics obtained from real-time 3D tracking of viral
particles in live cells. (1483-Pos/B604)
CP-42 Brown, C. M., M. A. Digman, E. Gratton, A. R.
Horwitz. Measuring protein binding kinetics at submicron resolution from
high speed Total Internal Reflection Fluorescence Microscopy Images.
(2314-Platform Talk)
CP-43 Sanchez, S. A., M.
A. Tricerri, A. Gomes, V. Levi, A. C. de Oliveira, E. Gratton. Reconstituted
HDL particles as an alternative acceptor to remove cholesterol in vitro and in
vivo. (2439-Pos/B106)
CP-44 Celli, A., E. Gratton. Lipid organization
fluctuations in model membranes studied by two photon fluorescence microscopy.
(2464-Pos/B131)
CP-45
Gratton, E., Tracking Protein-coated Particles in 3D.
Invited Speaker. American Physical Society, Baltimore, MD, March 13-17, 2006.
Optical
Society of America, March 18-23, 2006
CP-46 Tanner, K., E. D’Amico, A. Kaczmarowski, S. Kukreti,
J. Malpeli, W. W. Mantulin, E. Gratton. Spectrally Resolved
Neurophotonics: The Optical BOLD Effect and Vascular Components in the
Mammalian Brain.
CP-47 Gratton, E., K. Tanner,
E. Beitel, E. D’Amico, W. W. Mantulin. Effects of
Vasodilation on Intrinsic Optical Signals.
CP-48 Simonson, P. D., E.
D’Amico, E. Gratton. Proposal and Proof of Principle for a Novel Optical Biopsy
Needle: Modulating an Optical Needles Reflectivity Alters the Average Photon
Path in Scattering Media.
CP-49 Machado, N. G., A.
Perlman, E. Gratton. Near-Infrared Spectroscopy and the Swallowing Event.
CP-50 Gatto, R. G., E. D’Amico,
W. Mantulin, E. Gratton, F. Charbel. Optical
Microprobe for Blood Clot Detection.
CP-51 Rossow, M., E. Gratton,
E. D’Amico, W. W. Mantulin, R. Gatto. Blood Flow Measurements and Clot
Detection with Near-Infrared Spectroscopy.
CP-52
Gratton, E., M.
Digman. Lipid Rafts and Cell Function (D2). Keystone Symposium,
March 23-28, 2006.
CP-53
Tahari, A. K.,
and E. Gratton. Fluorescence correlation spectroscopy in turbid
media: Application to the detection and analysis of oligomeric complexes
of Alzheimer’s beta-peptide in CSF. ASCI/AAP 2006 Joint Meeting, Chicago,
IL, April 28–30, 2006.
CP-54
Gratton, E.,
Kavli Institute for Theoretical Physics. May 8, 2006.
CP-55
Gratton, E., "B5" Advanced Microscopy course and the
Bioimaging Symposium Biochemistry and Molecular Biology Department, University
of Southern Denmark on June 2006.
CP-56
Gratton, E., S. Sanchez. EMBO Advanced Microscopy Course,
University of Buenos Aires, Argentina , August 6-18,
2006.
CP-57
Gratton, E.,
Program Committee, Fifth Inter-Institute Workshop on Optical Diagnostic Imaging
from Bench to Bedside at the National Institutes of Health, Bethesda, Maryland,
August 27-30, 2006.
CP-58
Gratton, E.,
Tracking protein-coated particles in 3D. XVIII
Congresso Nazionale della Societa' Italiana di Biofisica Pura e Applicata
(SIBPA), Palermo, Sicily, Italy, September 17-21, 2006.
CP-59
Gratton, E.,
Particle Tracking in 3-D: Chromatin Structure and Dynamics. CeNS Workshop,
Venice International University, Italy , September
25-29, 2006.
CP-60
Gratton, E.,
Fluorescence Correlation Spectroscopy. Fluoro 2006, National Marine Science Center,
University of New England, Coffs Harbour, NSW, Australia, October 2-6, 2006.
CP-61
Gratton, E.,
Dynamic Cell Imaging with the Conforcor Microscope. Distinguished Lecture
Series at Fox Chase Cancer Center, Philadelphia, PA, November
9, 2006.
CP-62
Gratton, E.,
Raster Image Correlation Spectroscopy. Advanced Optical Imaging Workshop,
University of Melbourne, Australia, November 20-21,
2006.
51st Annual
Meeting of the Biophysical Society, Baltimore, Maryland, 2007
CP-63 Gratton, E., Number Fluctuations and Aggregation in
Live Cells. Advanced Optical Methods Workshop 2006, Berkeley, CA, January 17-19, 2007.
CP-64 Jee-Hyun Choi, Martin Wolf, Vladislav Toronov, Ursula
Wolf, Antonios Michalos, and Enrico Gratton. Spatio-temporal analysis of the cerebral spontaneous oscillations. 37th
Annual Meeting of the Society for Neuroscience, San Diego, California.
CP-65 Shwayta Kukreti, Albert E
Cerussi, V W Tanamai, Bruce Tromberg, and Enrico Gratton. Intrinsic markers of breast tumors. P41 Principal Investigator Meeting
Bethesda, Maryland. 19-20 June 2007.
CP-66 Kaveh Azartash and Enrico Gratton. Measuring the deformation of collagen matrix
in response to cell migration detected with digital holographic microscopy. 2nd
Frontiers in Biomedical Devices Conference, Irvine, California, 2007.
CP-67 Kandice Tanner, Shuo Tang, and Enrico Gratton. Dynamics of cell migration for cells embedded
in collagen using a multimodal platform of optical coherence tomography,
multi-photon excitation and second harmonic generation. 2007 APS March
Meeting, Denver, Colorado, 2007.
CP-68 Molly J Rossow, William W Mantulin, and Enrico
Gratton. An optical technique for fluid
velocity measurement applicable to intra-operative blood flow. 51st
Annual Meeting of the Biophysical Society, Baltimore, Maryland, 2007. Biophys J Supplement:
332a, 1565-Pos/B618, 2007.
CP-69 Kandice Tanner, Shuo Tang, and Enrico Gratton. Dynamics of cell migration for cells embedded
in collagen using a multimodal platform of optical coherence tomography,
multi-photon excitation and second harmonic generation. 51st Annual
Meeting of the Biophysical Society, Baltimore, Maryland, 2007. Biophys J Supplement:
517a, 2467-Pos/B682, 2007.
CP-70 Susana A Sanchez, Claudia
Toro, M Alejandra Tricerri, Enrico Gratton, and German Gunther. Interaction of rHDL particles with membranes containing cholesterol in
different lipid packing. 51st Annual Meeting of the Biophysical Society,
Baltimore, Maryland, 2007. Biophys J Supplement: 428a, 2052-Pos/B270, 2007.
CP-71 Jay R Unruh, Michelle A Digman, Hideaki Takahashi,
Judith Blaine, Sophia Y Breusegem, Nicholas P Barry, Moshe Levi, and Enrico
Gratton. Lipid dynamics in native rat
renal brush border membranes as measured by scanning fluorescence correlation
spectroscopy. 51st Annual Meeting of the Biophysical Society, Baltimore,
Maryland, 2007. Biophys J Supplement:
155a, 722-Pos/B566, 2007.
CP-72 Ryan A Colyer, Claudia Y
Lee, and Enrico Gratton. Time-resolved
frequency-domain fluorescence lifetime imaging microscopy in the
photon-counting regime. 51st Annual Meeting of the Biophysical Society,
Baltimore, Maryland, 2007. Biophys J Supplement: 321a, 1511-Pos/B564, 2007.
CP-73 Michelle A Digman, Rooshin Dalal, Claire M Brown,
Allen R Horwitz, and Enrico Gratton. Determination
of aggregates size and number of proteins from TIRF, LSM, and two photon
microscopy. 51st Annual Meeting of the Biophysical Society, Baltimore,
Maryland, 2007. Biophys J Supplement:
322a, 517-Pos/B570, 2007.
CP-74 Enrico Gratton, Claire M Brown, Allan R Horwitz, and
Michelle Digman. Velocity maps of
protein aggregates near adhesion sites form from TIRF data obtained with a fast
electron multiplier camera. 51st Annual Meeting of the Biophysical
Society, Baltimore, Maryland, 2007. Biophys J Supplement: 517a (2466-Pos/B681), 2007.
CP-75 Kaveh Azartash, Michelle Digman, Oliver Holub, and
Enrico Gratton. Deformation of collagen
matrix detected by digital holographic microscopy. 51st Annual Meeting
of the Biophysical Society, Baltimore, Maryland, 2007. Biophys
J Supplement, 2007.
CP-76
Kandice Tanner,
Shuo Tang, and Enrico Gratton. Dynamics
of cell migration for cells embedded in collagen using a multimodal platform of
optical coherence tomography, multi-photon excitation and second harmonic
generation. 2007 APS March Meeting, Denver, Colorado, 2007.
CP-77
Shwayta Kukreti, Albert E Cerussi, Bruce Tromberg, and
Enrico Gratton. Near-infrared tumor spectral
signature enhances optical mammography. ASCI/AAP Joint Meeting, Chicago,
Illinois, April 2007.
CP-78
Kaveh Azartash
and Enrico Gratton. Measuring the
deformation of collagen matrix in response to cell migration detected with
digital holographic microscopy. 2nd Frontiers in Biomedical Devices
Conference, Irvine, California, 2007.
CP-79
Shwayta Kukreti, Albert E Cerussi, V W Tanamai, Bruce
Tromberg, and Enrico Gratton. Intrinsic markers of breast
tumors. P41 Principal Investigator Meeting Bethesda, Maryland.
19-20 June 2007.
CP-80
Jee-Hyun Choi,
Martin Wolf, Vladislav Toronov, Ursula Wolf, Antonios Michalos, and Enrico
Gratton. Spatio-temporal analysis of
the cerebral spontaneous oscillations. 37th Annual Meeting of the
Society for Neuroscience, San Diego, California.
CP-81
Shwayta Kukreti,
Albert E Cerussi, V W Tanamai, Bruce J Tromberg, M Rita, H David, and Enrico
Gratton. Intrinsic near-infrared
spectroscopic biomarkers applied for evaluation of final pathological response
to neaoadjuvant chemotherapy. 30th Annual San Antonio Breast Cancer Symposium,
San Antonio, Texas, 2007.
CP-83 Enrico Gratton, Michelle A Digman, and Angelika Rück. Simultaneous FLIM measurement of the decay of
the donor and acceptor in a FRET pair. 52nd Annual Meeting of the
Biophysical Society, Long Beach, California, 2008. Biophys
J Supplement, 1601-Pos/B577, 2008.
CP-84 Claudia Toro, Susana A
Sánchez, Enrico Gratton, A Zanocco, E Lemp, and German Gunther. Effect of cholesterol in the solubilization process by
b-D-Fructofuranosyl-6-O-myristyl-a-D-Glucopyranoside (MMS). 52nd Annual
Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
2008.
CP-85 Travis I Moore, Theodore L Hazlett, Enrico Gratton,
and Tau-Mu Yi. Membrane diffusion
measured using fluorescence correlation spectroscopy in polarized S.
cerevisiae. 52nd Annual Meeting of the Biophysical Society, Long Beach,
California, 2008. Biophys J Supplement, 2008.
CP-86 Molly Rossow, William Mantulin, and Enrico Gratton. Blood flow mapping through spatial temporal
image correlation. 52nd Annual Meeting of the Biophysical Society, Long
Beach, California, 2008. Biophys J Supplement, 1691-Pos/B667, 2008.
CP-87 Susana A Sánchez, M Alejandra Tricerri, Andre Gomes, Andrea
De Oliveira, Valeria Levi, and Enrico Gratton. Changes in membrane water content after Cholesterol removal revealed by
Laurdan generalized polarization microscopy. 52nd Annual Meeting of the
Biophysical Society, Long Beach, California, 2008. Biophys
J Supplement, 2008.
CP-88 Kandice Tanner, Luca
Lanzano, and Enrico Gratton. Cell migration in collagen
matrices: assessment of local stiffness by fluctuation spectroscopy. 52nd Annual
Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
1595-Pos/B571, 2008.
CP-89 Sergio Perfetto, Marcela
Redigolo, and Enrico Gratton. Development of an instrument
for measuring extremely low concentrations of particles. 52nd Annual
Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
1617-Pos/B593, 2008.
CP-90 Kaveh Azartash and Enrico Gatton. Quantitative analysis of the dynamics of cell
and the extracellular matrix with digital holographic microscopy. 52nd
Annual Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
797-Pos/B640, 2008.
CP-91 Ryan A Colyer, Claudia Y
Lee, and Enrico Gratton. A novel fluorescence
lifetime imaging system that optimizes photon efficiency. 52nd Annual
Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
807-Pos/B650, 2008.
CP-92 Christian Hellriegel and Enrico Gratton. 3D
particle tracking in 2-photon microscopy using orbital scanning expanded. 52nd
Annual Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
809-Pos/B652, 2008.
CP-93 Giulia Ossato, Elisa
Frasnelli, Luca Lanzano, Michelle A Digman, J Lawrence Marsh, and Enrico
Gratton. Imaging HTT protein
aggregation in cells by fluctuation analysis. 52nd Annual
Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement,
233-Pos/B65, 2008.
CP-94 Jay R Unruh and Enrico Gratton. Number and brightness analysis for EMCCD
cameras. 52nd Annual Meeting of the Biophysical Society, Long Beach,
California, 2008. Biophys
J Supplement, 788-Pos/B631, 2008.
7th International Weber Symposium, Kauai, Hawaii, June
6-12, 2008
CP-95 Enrico Gratton. The SimFCS environment: from simulation to data acquisition and analysis.
7th International Weber Symposium, Kauai, Hawaii, June 6-12, 2008.
CP-96 German Gunther, Claudia A
Toro, Antonio Zanocco, M Rifo, Enrico Gratton, and Susana A Sánchez. Interaction of human erythrocyte with MMS detergent: changes in membrane
fluidity reported by Laurdan. 7th International Weber Symposium, Kauai, Hawaii, June
6-12, 2008.
CP-97 C K Choi, M Vicente-Manzanares, J Zareno, Claire M
Brown, A Mogilner, Michelle A Digman, D Kolin, Paul W Wiseman, Enrico Gratton,
and Alan R Horwitz. The assembly,
maturation, and disassembly of adhesions in migrating cells. 7th
International Weber Symposium, Kauai, Hawaii, June 6-12, 2008.
CP-98 Susana A Sánchez and
Enrico Gratton. Laurdan GP fluctuations in
biological membranes. 7th International Weber Symposium, Kauai, Hawaii, June
6-12, 2008.
CP-99 Yoshihiko Katayama, Ondrej Burkacky, Susanne Lange,
Christoph Bräuchle, Ralf-Peter Jansen, Enrico Gratton, and Don C Lamb. On the trail of single particles: 3D single
particle tracking in live cells. 7th International Weber Symposium,
Kauai, Hawaii, June 6-12, 2008.
CP-100
Giulia Ossato, Elisa Frasnelli, Luca Lanzano, Michelle A
Digman, J Lawrence Marsh, and Enrico Gratton. Imaging Htt protein aggregation in cells by fluctuation analysis. 7th
International Weber Symposium, Kauai, Hawaii, June 6-12, 2008.
CP-101
Michelle Digman, Giulia Ossato, Elisa Frasnelli, Gabriele
Buonaventura, Charity Aiken, J Lawrence Marsh, and Enrico Gratton. Huntingtin (Htt) oligomer formation in live cells. 7th
International Weber Symposium, Kauai, Hawaii, June 6-12, 2008.
CP-102
Enrico Gratton. Exploiting fluctuations to determine protein
aggregation and stoichiometry in cells. 7th International Weber
Symposium, Kauai, Hawaii, June 6-12, 2008.
CP-103
Christian
Hellriegel and Enrico Gratton. Latest
data from 3D single particle tracking. 7th International Weber
Symposium, Kauai, Hawaii, June 6-12, 2008.
Technical Reports
TR-1
vandeVen, M. and E. Gratton. Side-on
photomultipliers used in GigaHertz multifrequency cross-correlation phase
fluorimetry, LFD Report #2, 7 pp., 1988.
TR-2
Silva,
N. and E. Gratton. Calibration of steady-state spectrofluorometers, LFD Report
#4, 6 pp., 1988.
Patents
P-1
Gratton, E., US.
Patent 4,840,485. Frequency-domain
Cross-Correlation Fluorometry with Phase- Locked Loop Frequency Synthesizers.
June 20, 1989.
P-2
Gratton, E., M.
vandeVen and B. Barbieri, US Patent 5,323,010.
Time-Resolved Optical Array Detectors and CCD Cameras for Frequency
Domain Fluorometry and/or Phosphorimetry.
December 1, 1992.
P-3
Gratton, E. and
B. Barbieri US Patent 5,212,386. High Speed
Cross-Correlation Frequency Domain Fluorometry- Phosphorimetry. May 18, 1993.
P-4
Gratton, E., W.
W. Mantulin and M. vandeVen, US Patent 5,213,105. Frequency Domain Optical
Imaging Using Diffusion of Intensity Modulated Radiation. July 14, 1993.
P-5
Gratton, E., B.
Feddersen and D. Piston, US Patent 5,257,202. Simultaneous Multi-Frequency
Fluorometer. October 26, 1993.
P-6
Gratton, E., J.
Maier, M. A. Franceschini, S. Fantini, S. A. Walker, US Patent 5,492,118;
Canada Patent 2,137,878; Europe Patent 94309361.7; Japan Patent 332,542/94.
Determining Material Concentrations in Tissues.
February 20, 1996.
P-7
Gratton, E., S. Fantini, M. A. Franceschini, W. W.
Mantulin, B. Barbieri, US Patent 5,497,769. Photosensor
with Multiple Light Sources. March 12,
1996.
P-8
Gratton, E., S. Fantini, M. A. Franceschini, W. W.
Mantulin, B. Barbieri, US Patent 5,772,587.
Photosensor with Multiple Light Sources.
Continuation-in-part of Pat. 5,497,769 and 5,492,118. Filed: November 29, 1995,
Issued: June 30, 1998.
P-9
Dong, C.Y., E.
Gratton, P. So, US Patent 5,814,820.
Pump Probe Cross Correlation Fluorescence Frequency Domain Microscope
and Microscopy. September 29, 1998.
P-10
Gratton, E., S. Fantini, M. A. Franceschini, W. W.
Mantulin, B. Barbieri, US Patent 6,192,261.
Photosensor with Multiple Light Sources. Filed: May 4, 1998, Issued: February 20,
2001.
P-11
Franceschini, M. A., S. Fantini, E. Gratton, US Patent
6,216,021B. Method for
Measuring Absolute Saturation of Time-varying and Other Hemoglobin
Compartments. Filed: June 3&7, 1999,
Issued: April 10, 2001.
P-12
Barbieri, B. B., E. Gratton, US Patent 6,603,546. Rapid High
Throughput Spectrometer and Method. Filed: July 21, 2000, Issued: August 5,
2003.
P-13
Barbieri, B. B.,
E. Gratton, US Patent 6,794,659 [Division of US Patent 6,603,546]. Rapid High
Throughput Spectrometer and Method. Filed: June 4, 2003, Issued: September 21,
2004.
P-14
Gratton, E., G.
Motolese, A. Tahari, US Patent 20060256338. Methods and Devices for
Characterizing Particles in Clear and Turbid Media. Filed: January 27, 2006;
Issued: November 16, 2006.
P-15
Gratton E., S. Kukreti, A. E. Cerussi, B. J. Tromberg, US
Patent 20080009748. Method and Apparatus for the Determination of
Intrinsic Spectroscopic Tumor Markers by Broadband-Frequency Domain Technology.
Filed: May 16, 2007; Issued: January 10, 2008.