I am originally from St. Louis, Missouri. I
attended Rice University in
Houston, Texas, where I earned a Bachelor of Science in Electrical
and Computer Engineering in 2003. From 2003 to 2004 I worked as a
lab technician in Neal Waxham's lab
at the University of Texas
Health Science Center at Houston where I studied focal volume
characterization for fluorescence correlation spectroscopy. In 2004,
I entered the bioengineering graduate program at the University of
Illinois at Urbana Champaign and joined the Laboratory for Fluorescence
Dynamics with Enrico
Gratton as my advisor. I earned a Master of Science degree from
UIUC before moving with the lab to the University of California at
Irvine where I am continuing my PhD research.
My current project is to develop a novel technique that will
serve as the basis for a surgical instrument for measuring blood
flow in exposed blood vessels. It is important for surgeons to
measure blood flow during surgery, especially neurosurgery, to avoid
life-threatening complications. My technique, near-infrared
spatial-temporal image correlation spectroscopy (NIR-STICS) draws on
near-infrared spectroscopy (NIRS) and spatial-temporal image
correlation spectroscopy (STICS) to provide a quantitative map of
fluid velocity in arterioles over an area. NIR-STICS is non-invasive within
the context of surgery and has the potential to be adapted into
existing surgical microscopes.
Publications
- "Peak two-photon molecular brightness of fluorophoes is a robust measure of quantum efficiency and photostability." V. Iyer, M. Rossow, M. Waxham. J. Opt. Soc. Am. B. 23 7 (2006).
- "Focal Volume Characterization Using Multiphoton Fluorescence Correlation Spectroscopy (MP-FCS)," V. Iyer, M Rossow, and N. M. Waxham. Proc. of SPIE. 5323, 146 (2004).
- "Single-cycle Terahertz Electromagnetic Pulses: A New Test Bed for Physical Seismic Modeling," T. D. Dorney, M. Rossow, W. W. Symes, and D. M. Mittleman, Geophysics, Vol. 68, No. 1 (Jan.-Feb., 2003).
Abstracts and Posters
- "Blood flow mapping through spatial temporal image correlation." M. Rossow, W. Mantulin, and E. Gratton. 52nd Annual Meeting of the Biophysical Society, Long Beach, California, 2008. Biophys J Supplement, 1691-Pos/B667, 2008.
- "Flow Measurement Using Correlation Analysis of Optical Signals." M. Rossow, W. Mantulin, and E. Gratton. NTROI 2007.
- "An optical technique for fluid velocity measurement applicable to intra-operative blood flow." M. Rossow, W. Mantulin, and E. Gratton. 51st Annual Meeting of the Biophysical Society, Baltimore, Maryland, 2007. Biophys J Supplement: 332a, 1565-Pos/B618, 2007.
- "Blood flow measurements and clot detection with near-infrared spectroscopy." M. Rossow, R. Gatto, E. D'Amico, W. Mantulin, and E. Gratton. OSA Biomedical Topical Meeting (BIO), Fort Lauderdale, Florida, March 18-23, 2006. Biomedical Optics (Technical Digest). Optical Society of America, paper ME72, 2006.
- "Intra-Operative Blood Flow Measurement with Near-Infrared Spectroscopy using a Camera Based Detection System." M, Rossow, E. D'Amico, R. Gatto, F. Charbel, W. Mantulin, and E. Gratton. BMES 2006.
- "Characterization and optimization of multiphoton excitation (MPE) instrumentation using fluorescence correlation spectroscopy." V. Iyer, M. Rossow, P. Saggau, and M. N. Waxham. Biophs. J. 86: 607A, 2004.
Professional Activities
- Co-chair, UCI Engineering Graduate Student Council (Fall 2007)
- Judge, Orange County Science Fair (Spring 2007)
- Mentor to undergraduate engineering student (Fall 2005)
- President of Rice Chalice Student Unitarian Universalist Organization (Fall 2001-Spring 2003)
- Member Biomedical Engineering Society, Society of Women Engineers, Biophysical Society and Sigma Xi
Technical Skills
- Matlab
- Python
- Iron CAD
- C
- clean room and microfabrication procedures including photolithography
Certificates and Awards
- Scholarship recipient, Spring 2007. Society of Women Engineers Orange County Section
- Finalist, Society of Women Engineers national student poster competition 2007
- Medical Device Management Certificate Program. August 28-31, 2007. North Orange County Community College
- 1st LFD Workshop in Advanced Fluorescence Imaging and Dynamics. October 20-23, 2006. Laboratory for Fluorescence Dynamics, University of California, Irvine