The DIVER microscope system developed at the LFD can image large tissue areas in various imaging modes.
For example, a femur slice from a SMRTmRID mouse is shown in bright field (top), second harmonic generation (SHG, middle), and fluorescence lifetime imaging (FLIM, bottom) modes. The FLIM image is phasor mapped to segment Collagen I (red) from Collagen III (turquoise) rich regions.
The Laboratory for Fluorescence Dynamics (LFD) is a national research resource center for biomedical fluorescence spectroscopy, supported by the National Institute of General Medical Sciences (NIGMS P41GM103540) divisions of the National Institutes of Health (NIH) and the University of California, Irvine (UCI).
The founder and Principal Investigator of the LFD is Enrico Gratton. The Co-Investigator is Michelle Digman.
The LFD's main activities are:
Read more about the LFD's activities, history, funding, and organization.
The content on this website is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the University of California, Irvine.