Laboratory for Fluorescence Dynamics

A NIH research center for biomedical fluorescence spectroscopy at the University of California, Irvine

Search Publications

Publications by Year

Histogram

Tag Cloud

Histogram

Publications

The Laboratory for Fluorescence Dynamics' (LFD) database of publications contains more than 2100 journal articles, book chapters, conference proceedings, abstracts, patents, and theses by members of the LFD, and also selected publications of interest to the fluorescence community.
Electronic documents are not available publicly due to copyright restrictions. Reprints can be requested from the authors.

Recent LFD Publications

2018

  1. Staaf E, Hedde PN, Singh SB, Piguet J, Gratton E, Johansson S.
    Educated natural killer cells show dynamic movement of the activating receptor NKp46 and confinement of the inhibitory receptor Ly49A.
    Sci Signal. 2018; 11(517).
  2. Leemans SW, Dvornikov A, Gratton E.
    Adaptive optics in deep tissue microscopy.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 533a, 2638-Pos.
  3. Scipioni L, Diaspro A, Lanzanò L, Gratton E.
    AiryScan comprehensive superresolution correlation analysis.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 533a, 2641-Pos.
  4. Malacrida LS, Hedde PN, Ranjit S, Cardarelli F, Gratton E.
    Elucidating invisible barriers and obstacles to molecular diffusion in live cells by the spatial pair-correlation function: a connectivity view of the cell.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 166a, 835-Pos.
  5. Torrado B, Malacrida L, Badano JL, Irigoín F, Gratton E.
    Intracellular transport characterization of the transcription factor Gli2 by fluorescence correlation spectroscopy approaches.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 630a, 3123-Pos.
  6. Ranjit S, Dvornikov A, Levi M, Gratton E.
    Multicomponent analysis of phasor plot to decipher changes in metabolic trajectory of biological systems.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 167a, 843-Pos.
  7. Digman MA, Palomba F, Kong X, Yokomori K, Gratton E.
    Pair correlation analysis of Ku dynamics upon DNA damage.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 351a, 1740-Pos.
  8. Hedde PN, Malacrida L, Ahrar S, Siryaporn A, Gratton E.
    SideSPIM - a flexible multipurpose platform for light sheet microscopy.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 187a, 945-Plat.
  9. Cinco R, Hedde PN, Digman MA, Gratton E.
    Spatial characterization of NADH concentration and diffusion in cells and tissue.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 335a, 1662-Pos.
  10. Gratton E Dvornikov A.
    Spectral resolution in fluorescence microscopy in strongly scattering media.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 166a, 838-Pos.
  11. Murata MM, Kong X, Yokomori K, Digman MA.
    Fluorescence lifetime of NADH reveals PARP-dependent increase of oxidative phosphorylation critical for cell survival.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 83a, 425-Pos.
  12. Mah EJ, Yee AF, Digman MA.
    Metabolism modulation of cancer cells on varying substrate stiffnesses.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 19a, 101-Plat.
  13. Sameni S.
    Laurdan imaging and spectral phasor analysis reveals increased membrane fluidity in Huntington disease.
    62nd Annual Meeting of the Biophysical Society. San Francisco, California. February 17–21, 2018.
    Biophys J. 2018; 114(3, Suppl 1): 177a, 891-Pos.
  14. Kong L, Murata MM, Digman MA.
    Absence of REV3L promotes p53-regulated cancer cell metabolism in cisplatin-treated lung carcinoma cells.
    Biochem Biophys Res Commun. 2018; 496(1): 199-204.
  15. Mäntylä E, Chacko JV, Aho V, Parrish CR, Shahin V, Kann M, Digman MA, Gratton E, Vihinen-Ranta M.
    Viral highway to nucleus exposed by image correlation analyses.
    Sci Rep. 2018; 8(1): 1152. PMCID: PMC5773500
  16. Sameni S, Malacrida L, Tan Z, Digman MA.
    Alteration in fluidity of cell plasma membrane in Huntington disease revealed by spectral phasor Analysis.
    Sci Rep. 2018; 8(1): 734. PMCID: PMC5768877
  17. Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D’Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M.
    FXR/TGR5 dual agonist prevents progression of nephropathy in diabetes and obesity.
    J Am Soc Nephrol. 2018; 29(1). PMCID: PMC5748904
  18. Malacrida L, Hedde PN, Ranjit S, Cardarelli F, Gratton E.
    Visualization of barriers and obstacles to molecular diffusion in live cells by spatial pair-cross-correlation in two dimensions.
    Biomed Opt Express. 2018; 9(1): 303-321. PMCID: PMC5772584

2017

  1. Gach JS, Bouzin M, Wong MP, Chromikova V, Gorlani A, Yu KT, Sharma B, Gratton E, Forthal DN.
    Human Immunodeficiency Virus type-1 (HIV-1) evades antibody-dependent phagocytosis.
    PLoS Pathog. 2017; 13(12), e1006793. PMCID: PMC5760106
  2. Davey RJ, Digman MA, Gratton E, Moens PDJ.
    Quantitative image mean squared displacement (iMSD) analysis of the dynamics of Profilin 1 at the membrane of live cells.
    Methods. 2017; [Epub ahead of print].
  3. Trinh AL, Chen H, Chen Y, Hu Y, Li Z, Siegel ER, Linskey ME, Wang PH, Digman MA, Zhou YH.
    Tracking functional tumor cell subpopulations of malignant glioma by phasor fluorescence lifetime imaging microscopy of NADH.
    Cancers (Basel). 2017; 9(12), E168. PMCID: PMC5742816
  4. Bohórquez-Hernández A, Gratton E, Pacheco J, Asanov A, Vaca L.
    Cholesterol modulates the cellular localization of Orai1 channels and its disposition among membrane domains.
    Biochim Biophys Acta. 2017; 1862(12): 1481-1490.
  5. Digiacomo L, Cardarelli F, Pozzi D, Palchetti S, Digman MA, Gratton E, Capriotti AL, Mahmoudi M, Caracciolo G.
    An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles.
    Nanoscale. 2017; 9(44): 17254-17262. PMCID: PMC5700750
  6. Malacrida L, Jameson DM, Gratton E.
    A multidimensional phasor approach reveals LAURDAN photophysics in NIH-3T3 cell membranes.
    Sci Rep. 2017; 7(1): 9215. PMCID: PMC5569084
  7. Hedde PN, Malacrida L, Ahrar S, Siryaporn A, Gratton E.
    sideSPIM - selective plane illumination based on a conventional inverted microscope.
    Biomed Opt Express. 2017; 8(9): 3918-3937. PMCID: PMC5611913
  8. Liu L, Zhang SX, Liao W, Farhoodi HP, Wong CW, Chen CC, Ségaliny AI, Chacko JV, Nguyen LP, Lu M, Polovin G, Pone EJ, Downing TL, Lawson DA, Digman MA, Zhao W.
    Mechanoresponsive stem cells to target cancer metastases through biophysical cues.
    Sci Transl Med. 2017; 9(400), aan2966.
  9. Stortz M, Presman DM, Bruno L, Annibale P, Dansey MV, Burton G, Gratton E, Pecci A, Levi V.
    Mapping the dynamics of the Glucocorticoid Receptor within the nuclear landscape.
    Sci Rep. 2017; 7(1), 6219. PMCID: PMC5524710
  10. Herrington KA, Trinh AL, Dang C, O’Shaughnessy E, Hahn KM, Gratton E, Digman MA, Sütterlin C.
    Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation.
    Mol Biol Cell. 2017; 28(15): 2135-2145. PMCID: PMC5509425
  11. Xiao Z.
    Patient-derived induced pluripotent stem cells for Alzheimer's disease model and 3D culture of neurons on a multi-electrode array.
    Master in Biomedical Engineering, University of California, Irvine, 2017.
    Advisor: Michelle A Digman
  12. Bhattacharjee A, Datta R, Gratton E, Hochbaum AI.
    Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy.
    Sci Rep. 2017; 7(1), 3743. PMCID: PMC5473825
  13. Ranjit S, Dvornikov A, Dobrinskikh E, Wang X, Luo Y, Levi M, Gratton E.
    Measuring the effect of a Western diet on liver tissue architecture by FLIM autofluorescence and harmonic generation microscopy.
    Biomed Opt Express. 2017; 8(7): 3143-3154. PMCID: PMC5508820
  14. Ceccarelli A, di Venere A, Nicolai E, de Luca A, Rosato N, Gratton E, Mei G, Caccuri AM.
    New insight into the interaction of TRAF2 C-terminal domain with lipid raft microdomains.
    Biochim Biophys Acta. 2017; 1862(9): 813-822. PMCID: PMC5562040