Laboratory for Fluorescence Dynamics

A national research center for biomedical fluorescence spectroscopy at the University of California, Irvine


The Laboratory for Fluorescence Dynamics (LFD) provides a state-of-the-art laboratory for fluorescence measurements with technical assistance to visiting scientists.

Resources and Facilities

The LFD maintains customized facilities for:

  • Microscopy capable of GP, FCS, FLIM, RICS, TIRF, SPIM, DIVER, N&B, and 3D particle tracking measurements.
  • Spectroscopy in a cuvette, such as absorption spectrophotometry, steady-state fluorimetry, and time-resolved fluorometry (time and frequency domain).
  • Biochemistry including benches, cold room, hoods, centrifuges, and chromatographs.
  • Cell Culture including flow cabinets and incubators.
  • Computing including a public workstation lab with software for data analysis and visualization.

For inquiries about the availability of resources please see the online calendar and contact the user coordinator.

Scheduling Service

Inquiries about scheduling time on instrumentation and facilities should be directed to:

LFD User Coordinator
Phone: +1‑949‑824‑7085


No facility or usage fees are charged, except in the case of technical testing or sponsored research. The volunteer (or qualified associate) is required to personally conduct the experiments.

Non-US citizens who wish to use the LFD facilities for more than one week need a valid visa for the US. US visitor visa are not sufficient. Contact us and Sally L. Avila (Payroll Analyst, Biomedical Engineering Department) at least 50 days in advance to apply for a visa.

In order to fulfill UCI and NIH regulations, volunteers are required to:

  • Agree to UCI and LFD service policies
  • Be familiar with Bio and Laser safety
  • Provide proof of medical insurance
  • Submit all final peer-reviewed journal manuscripts that arise from work at the LFD to the digital archive PubMed Central upon acceptance for publication.

In order to continue funding for the LFD, all users of the facility, their affiliations, funding, and the types of work performed in the LFD must be recorded. Volunteers and users are asked to:

Although LFD personnel may become involved with volunteer programs, no collaborative arrangements (e.g. coauthorships) are implied or required. In cases where a volunteer's research may be closely allied to that of an LFD staff member, collaborative ventures may be instituted, but this is completely at the discretion of the interested parties.

The LFD should be acknowledged in any publications arising from the data collected in the LFD using the following text:

"The experiments reported in this publication were performed at the Laboratory for Fluorescence Dynamics (LFD) at the University of California, Irvine (UCI). The LFD is supported jointly by the National Institute of General Medical Sciences of the National Institutes of Health (P41GM103540), and UCI. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."

According to NIH Public Access Policy scientists are required to submit final peer-reviewed journal manuscripts that arise directly from NIH funds, such as the LFD grant, to the digital archive PubMed Central upon acceptance for publication.